PAX2 paired box 2 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: PAX2provided by VGNC
Official Full Name: paired box 2provided by VGNC
Primary source: VGNC:VGNC:5588
Locus tag: CK820_G0004129
See related: Ensembl:ENSPTRG00000002853
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 10

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	8	NC_072406.2 (112836144..112929236)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	10	NC_072408.1 (103450564..103543461)

Chromosome 8 - NC_072406.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

D10S2454 (e-PCR)
- UniSTS:474450

RH80285 (e-PCR)
- UniSTS:88437

Pax2 (e-PCR), detects polymorphism
- UniSTS:470672

D10S278 (e-PCR)
- UniSTS:147948

NoName (e-PCR)
- UniSTS:482033

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in anatomical structure development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: paired box protein Pax-2

Names: paired box gene 2; paired box protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072406.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

112836144..112929236

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054659863.2 → XP_054515838.1 paired box protein Pax-2 isoform X8
XM_016919120.3 → XP_016774609.1 paired box protein Pax-2 isoform X2

Conserved Domains (3) summary

smart00351
Location:47 → 171

PAX; Paired Box domain

pfam12403
Location:336 → 394

Pax2_C; Paired-box protein 2 C terminal

cl00084
Location:286 → 309

homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
XM_016919119.4 → XP_016774608.1 paired box protein Pax-2 isoform X2

Conserved Domains (3) summary

smart00351
Location:47 → 171

PAX; Paired Box domain

pfam12403
Location:336 → 394

Pax2_C; Paired-box protein 2 C terminal

cl00084
Location:286 → 309

homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
XM_003312731.6 → XP_003312779.2 paired box protein Pax-2 isoform X1

See identical proteins and their annotated locations for XP_003312779.2

Conserved Domains (3) summary

smart00351
Location:47 → 171

PAX; Paired Box domain

pfam12403
Location:336 → 421

Pax2_C; Paired-box protein 2 C terminal

cl00084
Location:286 → 309

homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
XM_001168828.6 → XP_001168828.3 paired box protein Pax-2 isoform X3

Related

ENSPTRP00000091068.1

Conserved Domains (3) summary

smart00351
Location:47 → 171

PAX; Paired Box domain

pfam12403
Location:336 → 446

Pax2_C; Paired-box protein 2 C terminal

cl00084
Location:286 → 309

homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
XM_063782074.1 → XP_063638144.1 paired box protein Pax-2 isoform X5
XM_016919121.3 → XP_016774610.1 paired box protein Pax-2 isoform X4

Conserved Domains (3) summary

smart00351
Location:47 → 171

PAX; Paired Box domain

pfam12403
Location:313 → 398

Pax2_C; Paired-box protein 2 C terminal

cl00084
Location:263 → 286

homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
XM_001168808.7 → XP_001168808.3 paired box protein Pax-2 isoform X6

Related

ENSPTRP00000071609.1

Conserved Domains (3) summary

smart00351
Location:47 → 171

PAX; Paired Box domain

pfam12403
Location:313 → 423

Pax2_C; Paired-box protein 2 C terminal

cl00084
Location:263 → 286

homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
XM_054659862.2 → XP_054515837.1 paired box protein Pax-2 isoform X7