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PRKCZ protein kinase C zeta [ Pan troglodytes (chimpanzee) ]

Gene ID: 743533, updated on 3-Apr-2024

Summary

Gene symbol
PRKCZ
Gene description
protein kinase C zeta
Locus tag
CK820_G0040570
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
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Genomic context

Location:
chromosome: 1
Exon count:
28
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 1 NC_072398.2 (229817123..229954595, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 1 NC_072398.1 (1344711..1482183)

Chromosome 1 - NC_072398.2Genomic Context describing neighboring genes Neighboring gene SKI proto-oncogene Neighboring gene uncharacterized LOC101059452 Neighboring gene FA core complex associated protein 20 Neighboring gene PRKCZ antisense RNA 1 Neighboring gene uncharacterized LOC129136387 Neighboring gene gamma-aminobutyric acid type A receptor subunit delta

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
protein kinase C zeta type
XP_024211611.1
XP_024211612.1
XP_024211613.1
XP_024211615.1
XP_024211616.1
XP_024211618.1
XP_024211619.1
XP_024211625.1
XP_024211628.1
XP_063643230.1
XP_063643244.1
XP_063643254.1
XP_063643258.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    229817123..229954595 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024355843.2XP_024211611.1  protein kinase C zeta type isoform X1

    UniProtKB/TrEMBL
    A0A2J8K8J8
    Conserved Domains (3) summary
    cd06404
    Location:1698
    PB1_aPKC; PB1 domain is an essential modular domain of the atypical protein kinase C (aPKC) which in complex with Par6 and Par3 proteins is crucial for establishment of apical-basal polarity of animal cells. PB1 domain is a modular domain mediating specific ...
    cd05617
    Location:236592
    STKc_aPKC_zeta; Catalytic domain of the Serine/Threonine Kinase, Atypical Protein Kinase C zeta
    cd21095
    Location:129183
    C1_aPKC_zeta; protein kinase C conserved region 1 (C1 domain) found in the atypical protein kinase C (aPKC) zeta type
  2. XM_024355847.3XP_024211615.1  protein kinase C zeta type isoform X4

    UniProtKB/TrEMBL
    A0A2J8K8N1, A0A2J8K8P3
    Conserved Domains (1) summary
    cl21453
    Location:53409
    PKc_like; Protein Kinases, catalytic domain
  3. XM_024355845.2XP_024211613.1  protein kinase C zeta type isoform X3

    UniProtKB/TrEMBL
    A0A2J8K8K0
    Conserved Domains (2) summary
    cd21095
    Location:2579
    C1_aPKC_zeta; protein kinase C conserved region 1 (C1 domain) found in the atypical protein kinase C (aPKC) zeta type
    cl21453
    Location:132488
    PKc_like; Protein Kinases, catalytic domain
  4. XM_024355860.2XP_024211628.1  protein kinase C zeta type isoform X4

    UniProtKB/TrEMBL
    A0A2J8K8N1, A0A2J8K8P3
    Conserved Domains (1) summary
    cl21453
    Location:53409
    PKc_like; Protein Kinases, catalytic domain
  5. XM_024355844.2XP_024211612.1  protein kinase C zeta type isoform X2

    Conserved Domains (2) summary
    pfam00130
    Location:2373
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    cl21453
    Location:128484
    PKc_like; Protein Kinases, catalytic domain
  6. XM_024355850.2XP_024211618.1  protein kinase C zeta type isoform X4

    UniProtKB/TrEMBL
    A0A2J8K8N1, A0A2J8K8P3
    Conserved Domains (1) summary
    cl21453
    Location:53409
    PKc_like; Protein Kinases, catalytic domain
  7. XM_063787160.1XP_063643230.1  protein kinase C zeta type isoform X4

    UniProtKB/TrEMBL
    A0A2J8K8N1
  8. XM_024355851.3XP_024211619.1  protein kinase C zeta type isoform X4

    UniProtKB/TrEMBL
    A0A2J8K8N1, A0A2J8K8P3
    Conserved Domains (1) summary
    cl21453
    Location:53409
    PKc_like; Protein Kinases, catalytic domain
  9. XM_024355857.2XP_024211625.1  protein kinase C zeta type isoform X4

    UniProtKB/TrEMBL
    A0A2J8K8N1, A0A2J8K8P3
    Conserved Domains (1) summary
    cl21453
    Location:53409
    PKc_like; Protein Kinases, catalytic domain
  10. XM_024355848.3XP_024211616.1  protein kinase C zeta type isoform X4

    UniProtKB/TrEMBL
    A0A2J8K8N1, A0A2J8K8P3
    Conserved Domains (1) summary
    cl21453
    Location:53409
    PKc_like; Protein Kinases, catalytic domain
  11. XM_063787174.1XP_063643244.1  protein kinase C zeta type isoform X4

    UniProtKB/TrEMBL
    A0A2J8K8N1
  12. XM_063787188.1XP_063643258.1  protein kinase C zeta type isoform X5

  13. XM_063787184.1XP_063643254.1  protein kinase C zeta type isoform X5