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MMP14 matrix metallopeptidase 14 [ Pan troglodytes (chimpanzee) ]

Gene ID: 742887, updated on 29-Mar-2024

Summary

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Official Symbol
MMP14provided by VGNC
Official Full Name
matrix metallopeptidase 14provided by VGNC
Primary source
VGNC:VGNC:7448
Locus tag
CK820_G0029622
See related
Ensembl:ENSPTRG00000006148
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 14
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 15 NC_072413.2 (21204075..21215441)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 14 NC_072412.1 (14428796..14439985)

Chromosome 15 - NC_072413.2Genomic Context describing neighboring genes Neighboring gene solute carrier family 7 member 7 Neighboring gene uncharacterized LOC134808342 Neighboring gene mitochondrial ribosomal protein L52 Neighboring gene uncharacterized LOC107968120 Neighboring gene LDL receptor related protein 10

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in collagen catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in skeletal system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in zymogen activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
matrix metalloproteinase-14
Names
matrix metallopeptidase 14 (membrane-inserted)
matrix metalloproteinase 14
XP_001157686.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072413.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    21204075..21215441
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001157686.8 → XP_001157686.2  matrix metalloproteinase-14

    UniProtKB/TrEMBL
    A0A2J8QJR0, A0A6D2YC78, H2Q7Z4
    Related
    ENSPTRP00000010422.6
    Conserved Domains (4) summary
    cd00094
    Location:316 → 508
    HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
    pfam00413
    Location:118 → 284
    Peptidase_M10; Matrixin
    pfam01471
    Location:36 → 88
    PG_binding_1; Putative peptidoglycan binding domain
    pfam11857
    Location:560 → 582
    DUF3377; Domain of unknown function (DUF3377)
Nucleotide Protein
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