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FRZB frizzled related protein [ Pan troglodytes (chimpanzee) ]

Gene ID: 742552, updated on 29-Mar-2024

Summary

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Official Symbol
FRZBprovided by VGNC
Official Full Name
frizzled related proteinprovided by VGNC
Primary source
VGNC:VGNC:434
Locus tag
CK820_G0001677
See related
Ensembl:ENSPTRG00000012708
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2B
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 13 NC_072411.2 (84873586..84906766, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 2B NC_072400.1 (84873549..84906920, complement)

Chromosome 13 - NC_072411.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC129143318 Neighboring gene DnaJ heat shock protein family (Hsp40) member C10 Neighboring gene U6 spliceosomal RNA Neighboring gene NCK associated protein 1 Neighboring gene ribosomal protein S25 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Wnt-protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in non-canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
secreted frizzled-related protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072411.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    84873586..84906766 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016950142.3 → XP_016805631.1  secreted frizzled-related protein 3

    UniProtKB/TrEMBL
    A0A2J8PRR1, A0A6D2WG11, H2QJ36
    Related
    ENSPTRP00000021732.5
    Conserved Domains (2) summary
    cd07441
    Location:32 → 157
    CRD_SFRP3; Cysteine-rich domain of the secreted frizzled-related protein 3 (SFRP3, alias FRZB), a Wnt antagonist
    cd03581
    Location:188 → 297
    NTR_Sfrp3_like; NTR domain, Secreted frizzled-related protein (Sfrp) 3-like subfamily; composed of proteins similar to human Sfrp3 and Sfrp4. Sfrps are soluble proteins containing an NTR domain C-terminal to a cysteine-rich Frizzled domain. They show diverse functions ...
Nucleotide Protein
Heading Accession and Version

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