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DOK1 docking protein 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 741064, updated on 11-Apr-2024

Summary

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Official Symbol
DOK1provided by VGNC
Official Full Name
docking protein 1provided by VGNC
Primary source
VGNC:VGNC:2929
Locus tag
CK820_G0035697
See related
Ensembl:ENSPTRG00000012100
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2A
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 12 NC_072410.2 (48197220..48206085, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 2A NC_072399.1 (74646464..74656010)

Chromosome 12 - NC_072410.2Genomic Context describing neighboring genes Neighboring gene meiosis 1 associated protein Neighboring gene torsin-1B-like Neighboring gene methylglutaconyl-CoA hydratase, mitochondrial-like Neighboring gene lysyl oxidase like 3 Neighboring gene HtrA serine peptidase 2 Neighboring gene AUP1 lipid droplet regulating VLDL assembly factor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in Ras protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
docking protein 1
Names
docking protein 1, 62kDa (downstream of tyrosine kinase 1)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072410.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    48197220..48206085 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054677963.2 → XP_054533938.1  docking protein 1 isoform X5

  2. XM_001161802.7 → XP_001161802.1  docking protein 1 isoform X1

    See identical proteins and their annotated locations for XP_001161802.1

    UniProtKB/TrEMBL
    A0A2J8KV57, A0A6D2VYK0, H2QI72
    Related
    ENSPTRP00000020765.2
    Conserved Domains (2) summary
    cd01203
    Location:151 → 253
    PTB_DOK1_DOK2_DOK3; Downstream of tyrosine kinase 1, 2, and 3 proteins phosphotyrosine-binding domain (PTBi)
    cl17171
    Location:6 → 119
    PH-like; Pleckstrin homology-like domain

  3. XM_016948841.4 → XP_016804330.1  docking protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A2I3RMJ1, A0A2J8KV67, A0A6D2XHJ8
    Related
    ENSPTRP00000065925.1
    Conserved Domains (1) summary
    cl17171
    Location:6 → 119
    PH-like; Pleckstrin homology-like domain

  4. XM_003309067.6 → XP_003309115.1  docking protein 1 isoform X2

    See identical proteins and their annotated locations for XP_003309115.1

    Conserved Domains (2) summary
    cd01203
    Location:140 → 242
    PTB_DOK1_DOK2_DOK3; Downstream of tyrosine kinase 1, 2, and 3 proteins phosphotyrosine-binding domain (PTBi)
    cl17171
    Location:11 → 108
    PH-like; Pleckstrin homology-like domain

  5. XM_054677962.2 → XP_054533937.1  docking protein 1 isoform X3

Nucleotide Protein
Heading Accession and Version

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