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FDFT1 farnesyl-diphosphate farnesyltransferase 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 740684, updated on 3-Apr-2024

Summary

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Official Symbol
FDFT1provided by VGNC
Official Full Name
farnesyl-diphosphate farnesyltransferase 1provided by VGNC
Primary source
VGNC:VGNC:3014
Locus tag
CK820_G0040359
See related
Ensembl:ENSPTRG00000019997
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 7 NC_072405.2 (17788870..17839453)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 8 NC_072406.1 (20931298..20982026)

Chromosome 7 - NC_072405.2Genomic Context describing neighboring genes Neighboring gene nei like DNA glycosylase 2 Neighboring gene activated RNA polymerase II transcriptional coactivator p15-like Neighboring gene cathepsin B Neighboring gene uncharacterized LOC107976197 Neighboring gene olfactory receptor 7E24-like Neighboring gene olfactory receptor 7E24-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Major chimpanzee-specific structural changes in sperm development-associated genes. Kim RN, et al. Funct Integr Genomics, 2011 Sep. PMID 21484476

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables farnesyl-diphosphate farnesyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables squalene synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cholesterol biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in farnesyl diphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
squalene synthase
NP_001267081.1
XP_009438497.1
XP_009438500.1
XP_009438501.1
XP_009438502.1
XP_054512400.1
XP_054512401.1
XP_054512402.1
XP_054512403.1
XP_054512404.1
XP_063672149.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001280152.1 → NP_001267081.1  squalene synthase

    See identical proteins and their annotated locations for NP_001267081.1

    Status: PROVISIONAL

    Source sequence(s)
    AK305291
    UniProtKB/TrEMBL
    A0A2J8Q9C8, G2HEX7
    Conserved Domains (1) summary
    TIGR01559
    Location:38 → 370
    squal_synth; farnesyl-diphosphate farnesyltransferase

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072405.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    17788870..17839453
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054656428.2 → XP_054512403.1  squalene synthase isoform X2

    UniProtKB/TrEMBL
    A0A2J8Q9C3, A0A6D2VTR0, H2QVR6

  2. XM_054656426.2 → XP_054512401.1  squalene synthase isoform X2

    UniProtKB/TrEMBL
    A0A2J8Q9C3, A0A6D2VTR0, H2QVR6

  3. XM_054656425.2 → XP_054512400.1  squalene synthase isoform X2

    UniProtKB/TrEMBL
    A0A2J8Q9C3, A0A6D2VTR0, H2QVR6

  4. XM_054656427.2 → XP_054512402.1  squalene synthase isoform X2

    UniProtKB/TrEMBL
    A0A2J8Q9C3, A0A6D2VTR0, H2QVR6

  5. XM_054656429.2 → XP_054512404.1  squalene synthase isoform X2

    UniProtKB/TrEMBL
    A0A2J8Q9C3, A0A6D2VTR0, H2QVR6

  6. XM_063816079.1 → XP_063672149.1  squalene synthase isoform X2

    UniProtKB/TrEMBL
    A0A2J8Q9C3, A0A6D2VTR0, H2QVR6

  7. XM_009440226.5 → XP_009438501.1  squalene synthase isoform X3

    See identical proteins and their annotated locations for XP_009438501.1

    UniProtKB/TrEMBL
    A0A2J8Q9C8, A0A2J8Q9E6
    Conserved Domains (1) summary
    cl00210
    Location:1 → 285
    Isoprenoid_Biosyn_C1; Isoprenoid Biosynthesis enzymes, Class 1

  8. XM_009440227.5 → XP_009438502.1  squalene synthase isoform X4

    See identical proteins and their annotated locations for XP_009438502.1

    Conserved Domains (1) summary
    cl00210
    Location:22 → 203
    Isoprenoid_Biosyn_C1; Isoprenoid Biosynthesis enzymes, Class 1

  9. XM_009440222.5 → XP_009438497.1  squalene synthase isoform X1

    UniProtKB/TrEMBL
    A0A2I3TD84, A0A2J8Q9C8, A0A2J8Q9D3, A0A6D2XG22
    Related
    ENSPTRP00000087156.1
    Conserved Domains (1) summary
    TIGR01559
    Location:89 → 421
    squal_synth; farnesyl-diphosphate farnesyltransferase

  10. XM_009440225.5 → XP_009438500.1  squalene synthase isoform X3

    See identical proteins and their annotated locations for XP_009438500.1

    UniProtKB/TrEMBL
    A0A2J8Q9C8, A0A2J8Q9E6
    Conserved Domains (1) summary
    cl00210
    Location:1 → 285
    Isoprenoid_Biosyn_C1; Isoprenoid Biosynthesis enzymes, Class 1
Nucleotide Protein
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