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FGR FGR proto-oncogene, Src family tyrosine kinase [ Pan troglodytes (chimpanzee) ]

Gene ID: 739516, updated on 11-Apr-2024

Summary

Official Symbol
FGRprovided by VGNC
Official Full Name
FGR proto-oncogene, Src family tyrosine kinaseprovided by VGNC
Primary source
VGNC:VGNC:9993
Locus tag
CK820_G0045796
See related
Ensembl:ENSPTRG00000000411 Ensembl:ENSPTRG00000048728
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
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Genomic context

Location:
chromosome: 1
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 1 NC_072398.2 (203356577..203379824)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 1 NC_072398.1 (27919237..27942391, complement)

Chromosome 1 - NC_072398.2Genomic Context describing neighboring genes Neighboring gene interferon alpha inducible protein 6 Neighboring gene translation machinery-associated protein 7-like Neighboring gene AT-hook DNA binding motif containing 1 Neighboring gene uncharacterized LOC129136675

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in extrinsic component of cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
tyrosine-protein kinase Fgr
Names
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
proto-oncogene tyrosine-protein kinase FGR
XP_016812730.1
XP_063639977.1
XP_063639985.1
XP_063639986.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    203356577..203379824
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016957241.4XP_016812730.1  tyrosine-protein kinase Fgr isoform X1

    UniProtKB/TrEMBL
    A0A2I3TU45, A0A2J8JP17, A0A6D2WLB6, H2PYF9
    Related
    ENSPTRP00000092790.1
    Conserved Domains (3) summary
    cd10367
    Location:140240
    SH2_Src_Fgr; Src homology 2 (SH2) domain found in Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog, Fgr
    cl17036
    Location:80137
    SH3; Src Homology 3 domain superfamily
    cl21453
    Location:267514
    PKc_like; Protein Kinases, catalytic domain
  2. XM_063783915.1XP_063639985.1  tyrosine-protein kinase Fgr isoform X1

    UniProtKB/TrEMBL
    A0A2J8JP17, A0A6D2WLB6, H2PYF9
  3. XM_063783916.1XP_063639986.1  tyrosine-protein kinase Fgr isoform X2

  4. XM_063783907.1XP_063639977.1  tyrosine-protein kinase Fgr isoform X1

    UniProtKB/TrEMBL
    A0A2J8JP17, A0A6D2WLB6, H2PYF9