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DTX1 deltex E3 ubiquitin ligase 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 739385, updated on 29-Mar-2024

Summary

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Official Symbol
DTX1provided by VGNC
Official Full Name
deltex E3 ubiquitin ligase 1provided by VGNC
Primary source
VGNC:VGNC:8401
Locus tag
CK820_G0015860
See related
Ensembl:ENSPTRG00000005480
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 12
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 10 NC_072408.2 (119889454..119930721)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 12 NC_072410.1 (118498286..118539427)

Chromosome 10 - NC_072408.2Genomic Context describing neighboring genes Neighboring gene 2'-5'-oligoadenylate synthetase 2 Neighboring gene mitochondrial inner membrane protease subunit 1-like Neighboring gene RAS protein activator like 1 Neighboring gene cilia and flagella associated protein 73

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase DTX1
Names
deltex 1, E3 ubiquitin ligase
deltex homolog 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072408.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    119889454..119930721
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016924300.3 → XP_016779789.1  E3 ubiquitin-protein ligase DTX1

    UniProtKB/TrEMBL
    A0A2J8MYE0, A0A6D2VXP2, H2Q6X2
    Related
    ENSPTRP00000009298.4
    Conserved Domains (3) summary
    smart00678
    Location:26 → 102
    WWE; Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis
    cd09633
    Location:480 → 612
    Deltex_C; Domain found at the C-terminus of deltex-like
    cd16671
    Location:408 → 476
    RING-H2_DTX1_4; RING finger, H2 subclass, found in E3 ubiquitin-protein ligase deltex1 (DTX1), deltex4 (DTX4), and similar proteins
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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