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RPS6KA5 ribosomal protein S6 kinase A5 [ Pan troglodytes (chimpanzee) ]

Gene ID: 739162, updated on 29-Mar-2024

Summary

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Official Symbol
RPS6KA5provided by VGNC
Official Full Name
ribosomal protein S6 kinase A5provided by VGNC
Primary source
VGNC:VGNC:8293
Locus tag
CK820_G0003135
See related
Ensembl:ENSPTRG00000006631
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 14
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 15 NC_072413.2 (88876280..89064969, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 14 NC_072412.1 (82139657..82349444, complement)

Chromosome 15 - NC_072413.2Genomic Context describing neighboring genes Neighboring gene tetratricopeptide repeat domain 7B Neighboring gene small ribosomal subunit protein uS13-like Neighboring gene uncharacterized LOC104002135 Neighboring gene U7 small nuclear RNA Neighboring gene D-glutamate cyclase Neighboring gene small nucleolar RNA SNORA11

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calmodulin-dependent protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mitogen-activated protein kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein autophosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ribosomal protein S6 kinase alpha-5
Names
ribosomal protein S6 kinase, 90kDa, polypeptide 5
XP_016782080.1
XP_016782083.1
XP_016782084.1
XP_016782085.1
XP_016782087.1
XP_016782088.1
XP_054521764.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072413.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    88876280..89064969 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016926595.4 → XP_016782084.1  ribosomal protein S6 kinase alpha-5 isoform X3

    Conserved Domains (3) summary
    smart00220
    Location:238 → 495
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14179
    Location:226 → 535
    STKc_MSK1_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Mitogen and stress-activated kinase 1
    cl21453
    Location:16 → 188
    PKc_like; Protein Kinases, catalytic domain

  2. XM_016926591.4 → XP_016782080.1  ribosomal protein S6 kinase alpha-5 isoform X1

    UniProtKB/TrEMBL
    A0A2J8PKY4, A0A6D2X615, H2Q8S3, K7DH81
    Related
    ENSPTRP00000066061.1
    Conserved Domains (3) summary
    smart00133
    Location:320 → 379
    S_TK_X; Extension to Ser/Thr-type protein kinases
    cd05613
    Location:48 → 337
    STKc_MSK1_N; N-terminal catalytic domain of the Serine/Threonine Kinase, Mitogen and stress-activated kinase 1
    cd14179
    Location:418 → 727
    STKc_MSK1_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Mitogen and stress-activated kinase 1

  3. XM_016926594.4 → XP_016782083.1  ribosomal protein S6 kinase alpha-5 isoform X2

    UniProtKB/TrEMBL
    A0A2I3RSK2, A0A2J8PL07, A0A6D2XGF8, H2Q8S3
    Related
    ENSPTRP00000067624.1
    Conserved Domains (3) summary
    smart00133
    Location:241 → 300
    S_TK_X; Extension to Ser/Thr-type protein kinases
    cd14179
    Location:339 → 648
    STKc_MSK1_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Mitogen and stress-activated kinase 1
    cl21453
    Location:1 → 258
    PKc_like; Protein Kinases, catalytic domain

  4. XM_016926596.4 → XP_016782085.1  ribosomal protein S6 kinase alpha-5 isoform X4

    Conserved Domains (2) summary
    cd14179
    Location:199 → 508
    STKc_MSK1_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Mitogen and stress-activated kinase 1
    cl21453
    Location:1 → 161
    PKc_like; Protein Kinases, catalytic domain

  5. XM_054665789.2 → XP_054521764.1  ribosomal protein S6 kinase alpha-5 isoform X5

  6. XM_016926599.4 → XP_016782088.1  ribosomal protein S6 kinase alpha-5 isoform X6

    Conserved Domains (3) summary
    smart00220
    Location:149 → 406
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14179
    Location:137 → 446
    STKc_MSK1_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Mitogen and stress-activated kinase 1
    cl21453
    Location:1 → 99
    PKc_like; Protein Kinases, catalytic domain

  7. XM_016926598.4 → XP_016782087.1  ribosomal protein S6 kinase alpha-5 isoform X6

    Conserved Domains (3) summary
    smart00220
    Location:149 → 406
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14179
    Location:137 → 446
    STKc_MSK1_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Mitogen and stress-activated kinase 1
    cl21453
    Location:1 → 99
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version

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