BCL2 BCL2 apoptosis regulator [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: BCL2provided by VGNC
Official Full Name: BCL2 apoptosis regulatorprovided by VGNC
Primary source: VGNC:VGNC:9936
Locus tag: CK820_G0011294
See related: Ensembl:ENSPTRG00000042753
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 18

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	17	NC_072415.2 (73158095..73357616, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	18	NC_072416.1 (72095483..72294066, complement)

Chromosome 17 - NC_072415.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

RH78390 (e-PCR)
- UniSTS:73233

GDB:214797 (e-PCR)
- UniSTS:156183

STS-AA007401 (e-PCR)
- UniSTS:6945

G10613 (e-PCR)
- UniSTS:71716

BCL2_50 (e-PCR)
- UniSTS:277028

D18S1264 (e-PCR)
- UniSTS:8767

RH91234 (e-PCR)
- UniSTS:89171

GDB:193042 (e-PCR)
- UniSTS:155736

GDB:193086 (e-PCR)
- UniSTS:155739

GDB:193087 (e-PCR)
- UniSTS:155740

PMC125347P1 (e-PCR)
- UniSTS:270490

RH119070 (e-PCR)
- UniSTS:138399

SHGC-37391 (e-PCR)
- UniSTS:19875

RH47111 (e-PCR)
- UniSTS:12986

RH68699 (e-PCR)
- UniSTS:18898

PMC137064P1 (e-PCR)
- UniSTS:270815

Bcl2 (e-PCR), detects polymorphism
- UniSTS:266976

SHGC-77927 (e-PCR)
- UniSTS:101351

PMC16825P1 (e-PCR)
- UniSTS:271602

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein heterodimerization activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein homodimerization activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in extrinsic apoptotic signaling pathway in absence of ligand	IEA Inferred from Electronic Annotation more info	PubMed
involved_in intrinsic apoptotic signaling pathway in response to DNA damage	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of intrinsic apoptotic signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrial outer membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: apoptosis regulator Bcl-2

Names: B-cell CLL/lymphoma 2; B-cell lymphoma protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072415.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

73158095..73357616 complement

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GenBank, FASTA, Sequence Viewer (Graphics)