FAS Fas cell surface death receptor [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: FASprovided by VGNC
Official Full Name: Fas cell surface death receptorprovided by VGNC
Primary source: VGNC:VGNC:3850
Locus tag: CK820_G0004371
See related: Ensembl:ENSPTRG00000002730
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 10

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	8	NC_072406.2 (101195501..101236707)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	10	NC_072408.1 (91824655..91857643)

Chromosome 8 - NC_072406.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

D10S2281 (e-PCR)
- UniSTS:79142

D8S2279 (e-PCR)
- UniSTS:473907

TNFRSF6_1709 (e-PCR)
- UniSTS:277831

SHGC-30908 (e-PCR)
- UniSTS:57418

RH11007 (e-PCR)
- UniSTS:72023

GDB:362780 (e-PCR)
- UniSTS:156762

GDB:362783 (e-PCR)
- UniSTS:156763

GDB:362785 (e-PCR)
- UniSTS:156764

GDB:681362 (e-PCR)
- UniSTS:158618

G65659 (e-PCR)
- UniSTS:225450

GDB:682143 (e-PCR)
- UniSTS:158637

GDB:682147 (e-PCR)
- UniSTS:158638

RH91808 (e-PCR)
- UniSTS:89274

csnptnfrsf6-pcr3-1 (e-PCR)
- UniSTS:243159

csnptnfrsf6-pcr4-1 (e-PCR)
- UniSTS:243160

csnptnfrsf6-pcr5-1 (e-PCR)
- UniSTS:243161

csnptnfrsf6-pcr6-1 (e-PCR)
- UniSTS:243162

csnptnfrsf6-pcr7-1 (e-PCR)
- UniSTS:243163

PMC96480P1 (e-PCR)
- UniSTS:273628

csnptnfrsf6-pcr8-1 (e-PCR)
- UniSTS:243164

csnptnfrsf6-pcr9-1 (e-PCR)
- UniSTS:243165

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed
enables tumor necrosis factor receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in activation-induced cell death of T cells	IEA Inferred from Electronic Annotation more info	PubMed
involved_in extrinsic apoptotic signaling pathway in absence of ligand	IEA Inferred from Electronic Annotation more info	PubMed
involved_in immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in motor neuron apoptotic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in necroptotic signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of apoptotic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of stress-activated MAPK cascade	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of CD95 death-inducing signaling complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in external side of plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in membrane raft	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: tumor necrosis factor receptor superfamily member 6

Names: Fas (TNF receptor superfamily, member 6); tumor necrosis factor receptor superfamily, member 6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072406.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

101195501..101236707

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063780864.1 → XP_063636934.1 tumor necrosis factor receptor superfamily member 6 isoform X3

UniProtKB/TrEMBL

A0A2J8PEC5, A0A6D2Y0H6, H2R2U8
XM_054659770.2 → XP_054515745.1 tumor necrosis factor receptor superfamily member 6 isoform X3

UniProtKB/TrEMBL

A0A2J8PEC5, A0A6D2Y0H6, H2R2U8
XM_063780865.1 → XP_063636935.1 tumor necrosis factor receptor superfamily member 6 isoform X3

UniProtKB/TrEMBL

A0A2J8PEC5, A0A6D2Y0H6, H2R2U8
XM_063780868.1 → XP_063636938.1 tumor necrosis factor receptor superfamily member 6 isoform X6
XM_063780866.1 → XP_063636936.1 tumor necrosis factor receptor superfamily member 6 isoform X4

UniProtKB/TrEMBL

A0A2I3RJ00, A0A2J8PED7, A0A6D2XVR3
XM_016918825.4 → XP_016774314.1 tumor necrosis factor receptor superfamily member 6 isoform X1

UniProtKB/TrEMBL

A0A2I3TG87
XM_063780867.1 → XP_063636937.1 tumor necrosis factor receptor superfamily member 6 isoform X5
XM_016918826.4 → XP_016774315.1 tumor necrosis factor receptor superfamily member 6 isoform X2

UniProtKB/TrEMBL

A0A2I3TG87