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HTR2B 5-hydroxytryptamine receptor 2B [ Pan troglodytes (chimpanzee) ]

Gene ID: 737647, updated on 3-Apr-2024

Summary

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Official Symbol
HTR2Bprovided by VGNC
Official Full Name
5-hydroxytryptamine receptor 2Bprovided by VGNC
Primary source
VGNC:VGNC:7409
Locus tag
CK820_G0010879
See related
Ensembl:ENSPTRG00000013022
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2B
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 13 NC_072411.2 (133349476..133377742, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 2B NC_072400.1 (133267440..133288844, complement)

Chromosome 13 - NC_072411.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107973953 Neighboring gene chromosome 13 C2orf72 homolog Neighboring gene proteasome 26S subunit, non-ATPase 1 Neighboring gene armadillo repeat containing 9 Neighboring gene UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled serotonin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables neurotransmitter receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in heart development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phospholipase C-activating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of behavior IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in release of sequestered calcium ion into cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in smooth muscle contraction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in vasoconstriction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in dendrite IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
5-hydroxytryptamine receptor 2B
Names
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072411.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    133349476..133377742 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001144172.6 → XP_001144172.1  5-hydroxytryptamine receptor 2B isoform X1

    See identical proteins and their annotated locations for XP_001144172.1

    UniProtKB/TrEMBL
    A0A2J8NF67, A0A6D2XZQ8, H2QJL0
    Related
    ENSPTRP00000022266.2
    Conserved Domains (1) summary
    cd15306
    Location:55 → 398
    7tmA_5-HT2B; serotonin receptor subtype 2B, member of the class A family of seven-transmembrane G protein-coupled receptors

  2. XM_063790848.1 → XP_063646918.1  5-hydroxytryptamine receptor 2B isoform X1

    UniProtKB/TrEMBL
    A0A2J8NF67, A0A6D2XZQ8, H2QJL0

  3. XM_063790849.1 → XP_063646919.1  5-hydroxytryptamine receptor 2B isoform X3

  4. XM_016950683.4 → XP_016806172.1  5-hydroxytryptamine receptor 2B isoform X2

    Conserved Domains (1) summary
    cd15306
    Location:30 → 373
    7tmA_5-HT2B; serotonin receptor subtype 2B, member of the class A family of seven-transmembrane G protein-coupled receptors

RNA

  1. XR_010149913.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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