LIF LIF interleukin 6 family cytokine [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: LIFprovided by VGNC
Official Full Name: LIF interleukin 6 family cytokineprovided by VGNC
Primary source: VGNC:VGNC:14779
Locus tag: CK820_G0024498
See related: Ensembl:ENSPTRG00000014236
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 22

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	23	NC_086016.1 (32370902..32377271, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	22	NC_072420.1 (25403300..25409632, complement)

Chromosome 23 - NC_086016.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

NoName (e-PCR)
- UniSTS:481059

NoName (e-PCR)
- UniSTS:483713

RH27829 (e-PCR)
- UniSTS:90754

GDB:624823 (e-PCR)
- UniSTS:158363

GDB:625815 (e-PCR)
- UniSTS:158366

SHGC-145300 (e-PCR)
- UniSTS:174504

SHGC-7772 (e-PCR)
- UniSTS:44530

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables cytokine activity	IEA Inferred from Electronic Annotation more info	PubMed
enables growth factor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables leukemia inhibitory factor receptor binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in leukemia inhibitory factor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of cell population proliferation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: leukemia inhibitory factor

Names: leukemia inhibitory factor (cholinergic differentiation factor)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_086016.1 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

32370902..32377271 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_016938951.4 → XP_016794440.1 leukemia inhibitory factor

UniProtKB/TrEMBL

A0A2J8QNK8, A0A6D2XLW8, H2QLG8

Related

ENSPTRP00000024522.4

Conserved Domains (1) summary

smart00080
Location:34 → 191

LIF_OSM; leukemia inhibitory factor