U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MAP3K2 mitogen-activated protein kinase kinase kinase 2 [ Pan troglodytes (chimpanzee) ]

Gene ID: 736244, updated on 29-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
MAP3K2provided by VGNC
Official Full Name
mitogen-activated protein kinase kinase kinase 2provided by VGNC
Primary source
VGNC:VGNC:14152
Locus tag
CK820_G0024233
See related
Ensembl:ENSPTRG00000012427
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 2B
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 13 NC_072411.2 (27977626..28066632, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 2B NC_072400.1 (27977623..28066926, complement)

Chromosome 13 - NC_072411.2Genomic Context describing neighboring genes Neighboring gene WW domain-binding protein 11-like Neighboring gene ERCC excision repair 3, TFIIH core complex helicase subunit Neighboring gene uncharacterized LOC107973761 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC104005164 Neighboring gene protein C, inactivator of coagulation factors Va and VIIIa Neighboring gene interacts with SUPT6H, CTD assembly factor 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
mitogen-activated protein kinase kinase kinase 2
XP_016805172.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072411.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    27977626..28066632 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016949683.4 → XP_016805172.1  mitogen-activated protein kinase kinase kinase 2

    UniProtKB/TrEMBL
    A0A2J8M1M7, A0A6D2XSZ1, H2QIN7
    Related
    ENSPTRP00000021280.4
    Conserved Domains (2) summary
    cd06405
    Location:44 → 122
    PB1_Mekk2_3; The PB1 domain is present in the two mitogen-activated protein kinase kinases MEKK2 and MEKK3 which are two members of the signaling kinase cascade involved in angiogenesis and early cardiovascular development. The PB1 domain of MEKK2 (and/or MEKK3) ...
    cd06652
    Location:353 → 616
    STKc_MEKK2; Catalytic domain of the Serine/Threonine Kinase, Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase Kinase 2
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Miscellaneous