Eif3j eukaryotic translation initiation factor 3, subunit J [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Eif3jprovided by RGD
Official Full Name: eukaryotic translation initiation factor 3, subunit Jprovided by RGD
Primary source: RGD:1593338
See related: Ensembl:ENSRNOG00000016459 AllianceGenome:RGD:1593338
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Eif3s1; eIF3 p35
Summary: Predicted to enable identical protein binding activity. Predicted to be involved in formation of cytoplasmic translation initiation complex. Predicted to be located in cytosol. Predicted to be part of eukaryotic translation initiation factor 3 complex. Orthologous to human EIF3J (eukaryotic translation initiation factor 3 subunit J). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Heart (RPKM 456.6), Muscle (RPKM 429.1) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 3q35

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	3	NC_086021.1 (129438715..129460953)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	3	NC_051338.1 (108985103..109007341)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	3	NC_005102.4 (113976687..113998925)

Chromosome 3 - NC_086021.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Knockdown of eIF-3-alpha enhances the expression of differentiation markers in PC12 cell.
Title: Eukaryotic translation initiation factor 3, subunit a, regulates the extracellular signal-regulated kinase pathway.

Submit: New GeneRIF Correction

General gene information

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Markers

RH133059 (e-PCR)
- UniSTS:216342

AA946404 (e-PCR)
- UniSTS:243384

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables identical protein binding	IEA Inferred from Electronic Annotation more info
enables identical protein binding	ISO Inferred from Sequence Orthology more info
enables translation initiation factor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in formation of cytoplasmic translation initiation complex	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
part_of eukaryotic 43S preinitiation complex	IEA Inferred from Electronic Annotation more info
part_of eukaryotic 48S preinitiation complex	IEA Inferred from Electronic Annotation more info
part_of eukaryotic translation initiation factor 3 complex	IBA Inferred from Biological aspect of Ancestor more info
part_of eukaryotic translation initiation factor 3 complex	IEA Inferred from Electronic Annotation more info
part_of eukaryotic translation initiation factor 3 complex	ISO Inferred from Sequence Orthology more info
part_of eukaryotic translation initiation factor 3 complex	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: eukaryotic translation initiation factor 3 subunit J

Names: eIF-3-alpha; eukaryotic translation initiation factor 3 subunit 1; eukaryotic translation initiation factor 3, subunit 1 alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.