Pgm5 phosphoglucomutase 5 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Pgm5provided by RGD
Official Full Name: phosphoglucomutase 5provided by RGD
Primary source: RGD:1307969
See related: Ensembl:ENSRNOG00000015406 AllianceGenome:RGD:1307969
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable magnesium ion binding activity. Predicted to be involved in carbohydrate metabolic process; myofibril assembly; and striated muscle tissue development. Predicted to be located in several cellular components, including focal adhesion; myofibril; and spot adherens junction. Predicted to be part of dystrophin-associated glycoprotein complex. Predicted to be active in several cellular components, including adherens junction; cell-substrate junction; and sarcolemma. Orthologous to human PGM5 (phosphoglucomutase 5). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Heart (RPKM 326.3), Uterus (RPKM 281.0) and 7 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 1q51

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (231752052..231939812, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (222325638..222513434, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (242582591..242765837, complement)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
NOT enables intramolecular phosphotransferase activity	ISO Inferred from Sequence Orthology more info
enables magnesium ion binding	IEA Inferred from Electronic Annotation more info
NOT enables phosphoglucomutase activity	IBA Inferred from Biological aspect of Ancestor more info
enables phosphoglucomutase activity	IEA Inferred from Electronic Annotation more info
NOT enables phosphoglucomutase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in carbohydrate metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info
involved_in cell adhesion	IEA Inferred from Electronic Annotation more info
involved_in myofibril assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in striated muscle tissue development	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in Z disc	IEA Inferred from Electronic Annotation more info
located_in Z disc	ISO Inferred from Sequence Orthology more info
is_active_in adherens junction	IBA Inferred from Biological aspect of Ancestor more info
located_in adherens junction	ISO Inferred from Sequence Orthology more info
is_active_in cell-substrate junction	IBA Inferred from Biological aspect of Ancestor more info
located_in cell-substrate junction	ISO Inferred from Sequence Orthology more info
located_in costamere	IEA Inferred from Electronic Annotation more info
located_in costamere	ISO Inferred from Sequence Orthology more info
located_in cytoplasmic side of plasma membrane	IEA Inferred from Electronic Annotation more info
located_in cytoplasmic side of plasma membrane	ISO Inferred from Sequence Orthology more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
part_of dystrophin-associated glycoprotein complex	IEA Inferred from Electronic Annotation more info
part_of dystrophin-associated glycoprotein complex	ISO Inferred from Sequence Orthology more info
located_in focal adhesion	IEA Inferred from Electronic Annotation more info
located_in focal adhesion	ISO Inferred from Sequence Orthology more info
located_in intercalated disc	IEA Inferred from Electronic Annotation more info
located_in intercalated disc	ISO Inferred from Sequence Orthology more info
is_active_in sarcolemma	IBA Inferred from Biological aspect of Ancestor more info
located_in sarcolemma	IEA Inferred from Electronic Annotation more info
located_in sarcolemma	ISO Inferred from Sequence Orthology more info
located_in spot adherens junction	IEA Inferred from Electronic Annotation more info
located_in spot adherens junction	ISO Inferred from Sequence Orthology more info
located_in stress fiber	IEA Inferred from Electronic Annotation more info
located_in stress fiber	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: phosphoglucomutase-like protein 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001191953.3 → NP_001178882.1 phosphoglucomutase-like protein 5

Status: VALIDATED

Source sequence(s)

JAXUCZ010000001

UniProtKB/Swiss-Prot

D3ZVR9

UniProtKB/TrEMBL

A0A8I6AHF8

Related

ENSRNOP00000092363.1, ENSRNOT00000112231.1

Conserved Domains (1) summary

cl38939
Location:10 → 567

phosphohexomutase; The alpha-D-phosphohexomutase superfamily includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Members of this family include the phosphoglucomutases (PGM1 and PGM2), phosphoglucosamine ...