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Ndufs6 NADH:ubiquinone oxidoreductase subunit S6 [ Rattus norvegicus (Norway rat) ]

Gene ID: 679739, updated on 13-Apr-2024

Summary

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Official Symbol
Ndufs6provided by RGD
Official Full Name
NADH:ubiquinone oxidoreductase subunit S6provided by RGD
Primary source
RGD:1584802
See related
Ensembl:ENSRNOG00000062531 AllianceGenome:RGD:1584802
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Ndufs6l1
Summary
Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to be part of mitochondrial respiratory chain complex I. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Heart (RPKM 1858.4), Muscle (RPKM 1129.0) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
1p11
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (31797400..31805965)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (29968833..29977423)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (32573204..32581785)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene lysophosphatidylcholine acyltransferase 1 Neighboring gene uncharacterized LOC120098986 Neighboring gene uncharacterized LOC120098989 Neighboring gene mitochondrial ribosomal protein L36 Neighboring gene iroquois homeobox 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. D-amino acid oxidase activity is inhibited by an interaction with bassoon protein at the presynaptic active zone. Popiolek M, et al. J Biol Chem, 2011 Aug 19. PMID 21700703, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
acts_upstream_of_or_within circulatory system development ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within fatty acid metabolic process ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within kidney development ISO
Inferred from Sequence Orthology
more info
  
involved_in mitochondrial electron transport, NADH to ubiquinone IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within mitochondrial respiratory chain complex I assembly ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within mitochondrion organization ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within multicellular organism growth ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within muscle contraction ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within reproductive system development ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within respiratory electron transport chain ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in mitochondrial inner membrane ISO
Inferred from Sequence Orthology
more info
  
part_of mitochondrial respiratory chain complex I IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitochondrial respiratory chain complex I ISO
Inferred from Sequence Orthology
more info
  
part_of mitochondrial respiratory chain complex I ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial
Names
NADH dehydrogenase (ubiquinone) Fe-S protein 6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial-like
NADH:ubiquinone oxidoreductase subunit S6-like 1
NP_001410618.1
XP_063129356.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001423689.1 → NP_001410618.1  NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    A6JUY2

RNA

  1. NR_186903.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    31797400..31805965
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063273286.1 → XP_063129356.1  NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial isoform X1

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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