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Rpl37 ribosomal protein L37 [ Mus musculus (house mouse) ]

Gene ID: 67281, updated on 16-Apr-2024

Summary

Official Symbol
Rpl37provided by MGI
Official Full Name
ribosomal protein L37provided by MGI
Primary source
MGI:MGI:1914531
See related
Ensembl:ENSMUSG00000041841 AllianceGenome:MGI:1914531
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
3110005M08Rik
Summary
Predicted to enable MDM2/MDM4 family protein binding activity; RNA binding activity; and ubiquitin ligase inhibitor activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in positive regulation of signal transduction by p53 class mediator. Located in synapse. Orthologous to human RPL37 (ribosomal protein L37). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in bladder adult (RPKM 440.1), CNS E11.5 (RPKM 405.1) and 28 other tissues See more
Orthologs
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Genomic context

Location:
15 A1; 15 1.99 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (5146127..5148626)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (5116613..5119140)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene complement component 7 Neighboring gene predicted gene, 25652 Neighboring gene caspase recruitment domain family, member 6 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E8583 Neighboring gene caspase recruitment domain family, member 6 Neighboring gene STARR-positive B cell enhancer ABC_E1171 Neighboring gene small nucleolar RNA, C/D box 72 Neighboring gene ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d pseudogene Neighboring gene predicted gene, 41256

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables MDM2/MDM4 family protein binding ISO
Inferred from Sequence Orthology
more info
 
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables growth factor binding ISO
Inferred from Sequence Orthology
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables rRNA binding IEA
Inferred from Electronic Annotation
more info
 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
 
enables ubiquitin ligase inhibitor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in positive regulation of signal transduction by p53 class mediator ISO
Inferred from Sequence Orthology
more info
 
involved_in translation IEA
Inferred from Electronic Annotation
more info
 
involved_in translation at postsynapse NAS
Non-traceable Author Statement
more info
PubMed 
involved_in translation at presynapse NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol TAS
Traceable Author Statement
more info
 
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of cytosolic large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
 
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
 
is_active_in postsynapse NAS
Non-traceable Author Statement
more info
PubMed 
is_active_in presynapse NAS
Non-traceable Author Statement
more info
PubMed 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 
is_active_in ribosome NAS
Non-traceable Author Statement
more info
PubMed 
is_active_in synapse EXP
Inferred from Experiment
more info
PubMed 
is_active_in synapse IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
large ribosomal subunit protein eL37
Names
60S ribosomal protein L37

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026069.4NP_080345.1  large ribosomal subunit protein eL37

    See identical proteins and their annotated locations for NP_080345.1

    Status: VALIDATED

    Source sequence(s)
    AC135079
    Consensus CDS
    CCDS37027.1
    UniProtKB/Swiss-Prot
    Q6ZWV1, Q9D823
    Related
    ENSMUSP00000046506.8, ENSMUST00000045356.9
    Conserved Domains (1) summary
    PTZ00073
    Location:188
    PTZ00073; 60S ribosomal protein L37; Provisional

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    5146127..5148626
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)