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Or2ag2b olfactory receptor family 2 subfamily AG member 2B [ Mus musculus (house mouse) ]

Gene ID: 66786, updated on 11-Apr-2024

Summary

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Official Symbol
Or2ag2bprovided by MGI
Official Full Name
olfactory receptor family 2 subfamily AG member 2Bprovided by MGI
Primary source
MGI:MGI:3030535
See related
Ensembl:ENSMUSG00000036744 AllianceGenome:MGI:3030535
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Olfr701; MOR283-1; 4932441H21Rik; 4933433E02Rik
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Expression
Restricted expression toward testis adult (RPKM 5.2) See more
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Genomic context

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Location:
7 E3; 7 56.08 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (106413336..106419916)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (106814129..106820709)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 2 subfamily AG member 17 Neighboring gene olfactory receptor family 2 subfamily AG member 18 Neighboring gene olfactory receptor family 13 subfamily N member 4 Neighboring gene olfactory receptor family 2 subfamily AG member 19

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Identification of novel post-transcriptional features in olfactory receptor family mRNAs. Shum EY, et al. Nucleic Acids Res, 2015 Oct 30. PMID 25908788, Free PMC Article
  2. Transcriptomes of mouse olfactory epithelium reveal sexual differences in odorant detection. Shiao MS, et al. Genome Biol Evol, 2012. PMID 22511034, Free PMC Article
  3. Update on the olfactory receptor (OR) gene superfamily. Olender T, et al. Hum Genomics, 2008 Sep. PMID 19129093, Free PMC Article
  4. Olfactory receptor genes expressed in distinct lineages are sequestered in different nuclear compartments. Yoon KH, et al. Proc Natl Acad Sci U S A, 2015 May 5. PMID 25897022, Free PMC Article
  5. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Pathways from PubChem

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General gene information

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Homology

Clone Names

  • MGC123418

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables olfactory receptor activity ISA
Inferred from Sequence Alignment
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
Inferred from Sequence Alignment
more info
 PubMed 
involved_in detection of chemical stimulus involved in sensory perception of smell IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within detection of chemical stimulus involved in sensory perception of smell ISA
Inferred from Sequence Alignment
more info
 PubMed 
acts_upstream_of_or_within sensory perception of smell ISA
Inferred from Sequence Alignment
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane ISA
Inferred from Sequence Alignment
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
olfactory receptor 701
Names
olfactory receptor MOR283-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001360747.1 → NP_001347676.1  olfactory receptor 701

    Status: VALIDATED

    Source sequence(s)
    AC116327, AK016560, AK017036
    Consensus CDS
    CCDS21672.1
    UniProtKB/TrEMBL
    Q9D3U9, Q9D4F9
    Related
    ENSMUSP00000130958.2, ENSMUST00000166880.3
    Conserved Domains (1) summary
    cd15421
    Location:26 → 300
    7tmA_OR2T-like; olfactory receptor subfamily 2T and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

  2. NM_028910.4 → NP_083186.2  olfactory receptor 701

    See identical proteins and their annotated locations for NP_083186.2

    Status: VALIDATED

    Source sequence(s)
    AK015248, AK016560, BC110461
    Consensus CDS
    CCDS21672.1
    UniProtKB/TrEMBL
    Q9D3U9, Q9D4F9
    Related
    ENSMUSP00000074868.2, ENSMUST00000075414.8
    Conserved Domains (1) summary
    cd15421
    Location:26 → 300
    7tmA_OR2T-like; olfactory receptor subfamily 2T and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    106413336..106419916
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017312235.1 → XP_017167724.1  olfactory receptor 701 isoform X1

    UniProtKB/TrEMBL
    Q9D3U9, Q9D4F9
    Conserved Domains (1) summary
    cd15421
    Location:26 → 300
    7tmA_OR2T-like; olfactory receptor subfamily 2T and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
Nucleotide Protein Strain
Heading Accession and Version

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