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Gng11 guanine nucleotide binding protein (G protein), gamma 11 [ Mus musculus (house mouse) ]

Gene ID: 66066, updated on 11-Apr-2024

Summary

Official Symbol
Gng11provided by MGI
Official Full Name
guanine nucleotide binding protein (G protein), gamma 11provided by MGI
Primary source
MGI:MGI:1913316
See related
Ensembl:ENSMUSG00000032766 AllianceGenome:MGI:1913316
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Hg3h1; 0610037B21Rik
Summary
Predicted to enable G-protein beta-subunit binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within signal transduction. Predicted to be located in plasma membrane. Predicted to be part of heterotrimeric G-protein complex. Is expressed in renal vasculature. Orthologous to human GNG11 (G protein subunit gamma 11). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in bladder adult (RPKM 17.3), liver E18 (RPKM 14.5) and 26 other tissues See more
Orthologs
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Genomic context

Location:
6 A1; 6 1.81 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (4003987..4008445)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (4003987..4008445)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_15006 Neighboring gene tissue factor pathway inhibitor 2 Neighboring gene guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 Neighboring gene RIKEN cDNA 4930528H21 gene Neighboring gene STARR-positive B cell enhancer ABC_E11732 Neighboring gene Bet1 golgi vesicular membrane trafficking protein

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (4) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G-protein beta-subunit binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of heterotrimeric G-protein complex IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
Names
heterotrimeric guanine nucleotide-binding protein 3h1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025331.2NP_079607.1  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11

    See identical proteins and their annotated locations for NP_079607.1

    Status: PROVISIONAL

    Source sequence(s)
    BC039062
    Consensus CDS
    CCDS39419.1
    UniProtKB/Swiss-Prot
    P61953, Q4QRN2
    Related
    ENSMUSP00000031670.9, ENSMUST00000031670.10
    Conserved Domains (1) summary
    smart00224
    Location:1273
    GGL; G protein gamma subunit-like motifs

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    4003987..4008445
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)