GUCY1A2 guanylate cyclase 1 soluble subunit alpha 2 [Bos taurus (cattle)] - Gene

Summary

Official Symbol: GUCY1A2provided by VGNC
Official Full Name: guanylate cyclase 1 soluble subunit alpha 2provided by VGNC
Primary source: VGNC:VGNC:29719
See related: BGD:BT16862; Ensembl:ENSBTAG00000044144
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 15

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	15	NC_037342.1 (16273674..16859786)

Chromosome 15 - NC_037342.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:: NC_037342.1 Chromosome 15 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables guanylate cyclase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables heme binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cGMP biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cGMP-mediated signaling	IEA Inferred from Electronic Annotation more info	PubMed
involved_in response to oxygen levels	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of guanylate cyclase complex, soluble	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: guanylate cyclase soluble subunit alpha-2

NP_001178270.1

EC 4.6.1.2

XP_059730935.1

EC 4.6.1.2

XP_059730936.1

EC 4.6.1.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001191341.1 → NP_001178270.1 guanylate cyclase soluble subunit alpha-2

See identical proteins and their annotated locations for NP_001178270.1

Status: PROVISIONAL

Source sequence(s)

NKLS02000015

UniProtKB/TrEMBL

E1BP75

Related

ENSBTAP00000053417.2, ENSBTAT00000061171.4

Conserved Domains (4) summary

smart00044
Location:483 → 672

CYCc; Adenylyl- / guanylyl cyclase, catalytic domain

pfam00211
Location:512 → 696

Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain

pfam07700
Location:148 → 267

HNOB; Haem-NO-binding

pfam07701
Location:314 → 501

HNOBA; Heme NO binding associated

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

NC_037342.1 Reference ARS-UCD2.0 Primary Assembly

Range

16273674..16859786

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_059874953.1 → XP_059730936.1 guanylate cyclase soluble subunit alpha-2 isoform X1
XM_059874952.1 → XP_059730935.1 guanylate cyclase soluble subunit alpha-2 isoform X1