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NR1H4 nuclear receptor subfamily 1 group H member 4 [ Canis lupus familiaris (dog) ]

Gene ID: 612928, updated on 23-Mar-2024

Summary

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Official Symbol
NR1H4provided by VGNC
Official Full Name
nuclear receptor subfamily 1 group H member 4provided by VGNC
Primary source
VGNC:VGNC:43944
See related
Ensembl:ENSCAFG00845006398
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 15
Exon count:
16
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 15 NC_051819.1 (40161103..40272109)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 15 NC_006597.4 (39876387..39987365)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 15 NC_049236.1 (39799183..39910169)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 15 NC_049275.1 (39418531..39529420)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 15 NC_049756.1 (39525061..39636033)

Chromosome 15 - NC_051819.1Genomic Context describing neighboring genes Neighboring gene SCY1 like pseudokinase 2 Neighboring gene solute carrier family 17 member 8 Neighboring gene uncharacterized LOC119868497 Neighboring gene uncharacterized LOC119881749 Neighboring gene protein lin-28 homolog A-like Neighboring gene growth arrest specific 2 like 3 Neighboring gene anoctamin 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Activation of farnesoid X receptor retards expansion of renal collecting duct cell-derived cysts via inhibition of CFTR-mediated Cl[-] secretion.
    Title: Activation of farnesoid X receptor retards expansion of renal collecting duct cell-derived cysts via inhibition of CFTR-mediated Cl(-) secretion.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables bile acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in bile acid signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
bile acid receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051819.1 Reference ROS_Cfam_1.0

    Range
    40161103..40272109
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038688387.1 → XP_038544315.1  bile acid receptor isoform X4

    UniProtKB/TrEMBL
    A0A8I3RTA2
    Related
    ENSCAFP00845008869.1, ENSCAFT00845011357.1
    Conserved Domains (2) summary
    cd06936
    Location:247 → 467
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:124 → 207
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

  2. XM_038688386.1 → XP_038544314.1  bile acid receptor isoform X3

    UniProtKB/TrEMBL
    A0A8C0LJE0, A0A8C0S616, A0A8P0STP9
    Conserved Domains (2) summary
    cd06936
    Location:251 → 471
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:124 → 211
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

  3. XM_038688382.1 → XP_038544310.1  bile acid receptor isoform X3

    UniProtKB/TrEMBL
    A0A8C0LJE0, A0A8C0S616, A0A8P0STP9
    Conserved Domains (2) summary
    cd06936
    Location:251 → 471
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:124 → 211
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

  4. XM_038688384.1 → XP_038544312.1  bile acid receptor isoform X3

    UniProtKB/TrEMBL
    A0A8C0LJE0, A0A8C0S616, A0A8P0STP9
    Conserved Domains (2) summary
    cd06936
    Location:251 → 471
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:124 → 211
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

  5. XM_038688385.1 → XP_038544313.1  bile acid receptor isoform X3

    UniProtKB/TrEMBL
    A0A8C0LJE0, A0A8C0S616, A0A8P0STP9
    Conserved Domains (2) summary
    cd06936
    Location:251 → 471
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:124 → 211
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

  6. XM_038688383.1 → XP_038544311.1  bile acid receptor isoform X3

    UniProtKB/TrEMBL
    A0A8C0LJE0, A0A8C0S616, A0A8P0STP9
    Conserved Domains (2) summary
    cd06936
    Location:251 → 471
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:124 → 211
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

  7. XM_038688380.1 → XP_038544308.1  bile acid receptor isoform X1

    UniProtKB/TrEMBL
    A0A8C0R707, A0A8C0S6D2
    Conserved Domains (2) summary
    cd06936
    Location:260 → 480
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cl02596
    Location:133 → 220
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

  8. XM_038688381.1 → XP_038544309.1  bile acid receptor isoform X2

    UniProtKB/TrEMBL
    A0A8I3N2S7, A0A8P0N9A5
    Related
    ENSCAFP00845008917.1, ENSCAFT00845011416.1
    Conserved Domains (2) summary
    cd06936
    Location:256 → 476
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:133 → 216
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049275.1 Alternate UMICH_Zoey_3.1

    Range
    39418531..39529420
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038496396.1 → XP_038352324.1  bile acid receptor isoform X4

    Conserved Domains (2) summary
    cd06936
    Location:247 → 467
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:124 → 207
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

  2. XM_038496395.1 → XP_038352323.1  bile acid receptor isoform X3

    Conserved Domains (2) summary
    cd06936
    Location:251 → 471
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:124 → 211
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

  3. XM_038496391.1 → XP_038352319.1  bile acid receptor isoform X3

    Conserved Domains (2) summary
    cd06936
    Location:251 → 471
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:124 → 211
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

  4. XM_038496393.1 → XP_038352321.1  bile acid receptor isoform X3

    Conserved Domains (2) summary
    cd06936
    Location:251 → 471
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:124 → 211
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

  5. XM_038496394.1 → XP_038352322.1  bile acid receptor isoform X3

    Conserved Domains (2) summary
    cd06936
    Location:251 → 471
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:124 → 211
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

  6. XM_038496392.1 → XP_038352320.1  bile acid receptor isoform X3

    Conserved Domains (2) summary
    cd06936
    Location:251 → 471
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:124 → 211
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

  7. XM_038496389.1 → XP_038352317.1  bile acid receptor isoform X1

    Conserved Domains (2) summary
    cd06936
    Location:260 → 480
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cl02596
    Location:133 → 220
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

  8. XM_038496390.1 → XP_038352318.1  bile acid receptor isoform X2

    Conserved Domains (2) summary
    cd06936
    Location:256 → 476
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:133 → 216
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049756.1 Alternate UNSW_CanFamBas_1.0

    Range
    39525061..39636033
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038622718.1 → XP_038478646.1  bile acid receptor isoform X3

    Conserved Domains (2) summary
    cd06936
    Location:251 → 471
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:124 → 211
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

  2. XM_038622714.1 → XP_038478642.1  bile acid receptor isoform X3

    Conserved Domains (2) summary
    cd06936
    Location:251 → 471
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:124 → 211
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

  3. XM_038622719.1 → XP_038478647.1  bile acid receptor isoform X4

    Conserved Domains (2) summary
    cd06936
    Location:247 → 467
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:124 → 207
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

  4. XM_038622716.1 → XP_038478644.1  bile acid receptor isoform X3

    Conserved Domains (2) summary
    cd06936
    Location:251 → 471
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:124 → 211
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

  5. XM_038622717.1 → XP_038478645.1  bile acid receptor isoform X3

    Conserved Domains (2) summary
    cd06936
    Location:251 → 471
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:124 → 211
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

  6. XM_038622715.1 → XP_038478643.1  bile acid receptor isoform X3

    Conserved Domains (2) summary
    cd06936
    Location:251 → 471
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:124 → 211
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

  7. XM_038622712.1 → XP_038478640.1  bile acid receptor isoform X1

    Conserved Domains (2) summary
    cd06936
    Location:260 → 480
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cl02596
    Location:133 → 220
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

  8. XM_038622713.1 → XP_038478641.1  bile acid receptor isoform X2

    Conserved Domains (2) summary
    cd06936
    Location:256 → 476
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:133 → 216
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049236.1 Alternate UU_Cfam_GSD_1.0

    Range
    39799183..39910169
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038558798.1 → XP_038414726.1  bile acid receptor isoform X4

    UniProtKB/TrEMBL
    A0A8I3RTA2
    Conserved Domains (2) summary
    cd06936
    Location:247 → 467
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:124 → 207
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

  2. XM_038558797.1 → XP_038414725.1  bile acid receptor isoform X3

    UniProtKB/TrEMBL
    A0A8C0LJE0, A0A8C0S616, A0A8P0STP9
    Conserved Domains (2) summary
    cd06936
    Location:251 → 471
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:124 → 211
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

  3. XM_038558793.1 → XP_038414721.1  bile acid receptor isoform X3

    UniProtKB/TrEMBL
    A0A8C0LJE0, A0A8C0S616, A0A8P0STP9
    Conserved Domains (2) summary
    cd06936
    Location:251 → 471
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:124 → 211
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

  4. XM_038558795.1 → XP_038414723.1  bile acid receptor isoform X3

    UniProtKB/TrEMBL
    A0A8C0LJE0, A0A8C0S616, A0A8P0STP9
    Conserved Domains (2) summary
    cd06936
    Location:251 → 471
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:124 → 211
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

  5. XM_038558796.1 → XP_038414724.1  bile acid receptor isoform X3

    UniProtKB/TrEMBL
    A0A8C0LJE0, A0A8C0S616, A0A8P0STP9
    Conserved Domains (2) summary
    cd06936
    Location:251 → 471
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:124 → 211
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

  6. XM_038558794.1 → XP_038414722.1  bile acid receptor isoform X3

    UniProtKB/TrEMBL
    A0A8C0LJE0, A0A8C0S616, A0A8P0STP9
    Conserved Domains (2) summary
    cd06936
    Location:251 → 471
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:124 → 211
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

  7. XM_038558791.1 → XP_038414719.1  bile acid receptor isoform X1

    UniProtKB/TrEMBL
    A0A8C0R707, A0A8C0S6D2
    Conserved Domains (2) summary
    cd06936
    Location:260 → 480
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cl02596
    Location:133 → 220
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

  8. XM_038558792.1 → XP_038414720.1  bile acid receptor isoform X2

    UniProtKB/TrEMBL
    A0A8I3N2S7, A0A8P0N9A5
    Conserved Domains (2) summary
    cd06936
    Location:256 → 476
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:133 → 216
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006597.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    39876387..39987365
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038450621.1 → XP_038306549.1  bile acid receptor isoform X4

    UniProtKB/TrEMBL
    A0A8I3RTA2
    Conserved Domains (2) summary
    cd06936
    Location:247 → 467
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:124 → 207
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

  2. XM_038450614.1 → XP_038306542.1  bile acid receptor isoform X3

    UniProtKB/TrEMBL
    A0A8C0LJE0, A0A8C0S616, A0A8P0STP9
    Conserved Domains (2) summary
    cd06936
    Location:251 → 471
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:124 → 211
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

  3. XM_038450578.1 → XP_038306506.1  bile acid receptor isoform X3

    UniProtKB/TrEMBL
    A0A8C0LJE0, A0A8C0S616, A0A8P0STP9
    Conserved Domains (2) summary
    cd06936
    Location:251 → 471
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:124 → 211
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

  4. XM_022403402.2 → XP_022259110.1  bile acid receptor isoform X3

    UniProtKB/TrEMBL
    A0A8C0LJE0, A0A8C0S616, A0A8P0STP9
    Conserved Domains (2) summary
    cd06936
    Location:251 → 471
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:124 → 211
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

  5. XM_038450605.1 → XP_038306533.1  bile acid receptor isoform X3

    UniProtKB/TrEMBL
    A0A8C0LJE0, A0A8C0S616, A0A8P0STP9
    Conserved Domains (2) summary
    cd06936
    Location:251 → 471
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:124 → 211
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

  6. XM_847866.6 → XP_852959.2  bile acid receptor isoform X3

    UniProtKB/TrEMBL
    A0A8C0LJE0, A0A8C0S616, A0A8P0STP9
    Conserved Domains (2) summary
    cd06936
    Location:251 → 471
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:124 → 211
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

  7. XM_861529.5 → XP_866622.2  bile acid receptor isoform X1

    UniProtKB/TrEMBL
    A0A8C0R707, A0A8C0S6D2
    Conserved Domains (2) summary
    cd06936
    Location:260 → 480
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cl02596
    Location:133 → 220
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

  8. XM_005629274.3 → XP_005629331.1  bile acid receptor isoform X2

    UniProtKB/TrEMBL
    A0A8I3N2S7, A0A8P0N9A5
    Conserved Domains (2) summary
    cd06936
    Location:256 → 476
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:133 → 216
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
Nucleotide Protein
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