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RPS6KA2 ribosomal protein S6 kinase A2 [ Canis lupus familiaris (dog) ]

Gene ID: 612448, updated on 5-Mar-2024

Summary

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Official Symbol
RPS6KA2provided by VGNC
Official Full Name
ribosomal protein S6 kinase A2provided by VGNC
Primary source
VGNC:VGNC:45739
See related
Ensembl:ENSCAFG00845004742
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
28
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 1 NC_051805.1 (54592807..54938176, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 1 NC_006583.4 (55202572..55547248, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 1 NC_049222.1 (54963546..55308688, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 1 NC_049261.1 (54489815..54835148, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 1 NC_049742.1 (54338945..54683764, complement)

Chromosome 1 - NC_051805.1Genomic Context describing neighboring genes Neighboring gene SFT2 domain containing 1 Neighboring gene mitochondrial pyruvate carrier 1 Neighboring gene uncharacterized LOC119870768 Neighboring gene uncharacterized LOC119870667 Neighboring gene ribonuclease T2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ribosomal protein S6 kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ribosomal protein S6 kinase alpha-2
XP_013968612.1
XP_013968614.1
XP_013968622.1
XP_022274604.1
XP_022274608.1
XP_038321774.1
XP_038321775.1
XP_038321776.1
XP_038321777.1
XP_038321778.1
XP_038321779.1
XP_038382454.1
XP_038382455.1
XP_038382456.1
XP_038382457.1
XP_038382458.1
XP_038382459.1
XP_038446745.1
XP_038446746.1
XP_038446747.1
XP_038446748.1
XP_038446749.1
XP_038446750.1
XP_038510542.1
XP_038510543.1
XP_038510544.1
XP_038510545.1
XP_038510546.1
XP_038510547.1
XP_855268.5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051805.1 Reference ROS_Cfam_1.0

    Range
    54592807..54938176 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038654615.1 → XP_038510543.1  ribosomal protein S6 kinase alpha-2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0MT56, A0A8P0PSW9, A0A8P0T3S5
    Related
    ENSCAFP00845006702.1, ENSCAFT00845008498.1
    Conserved Domains (2) summary
    cd05582
    Location:88 → 404
    STKc_RSK_N; N-terminal catalytic domain of the Serine/Threonine Kinase, 90 kDa ribosomal protein S6 kinase
    cd14178
    Location:436 → 728
    STKc_RSK3_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Ribosomal S6 kinase 3 (also called Ribosomal protein S6 kinase alpha-2 or 90kDa ribosomal protein S6 kinase 2)

  2. XM_038654617.1 → XP_038510545.1  ribosomal protein S6 kinase alpha-2 isoform X4

    UniProtKB/TrEMBL
    A0A8C0REI3, A0A8P0PC03, A0A8P0PSW9
    Conserved Domains (2) summary
    cd05582
    Location:61 → 377
    STKc_RSK_N; N-terminal catalytic domain of the Serine/Threonine Kinase, 90 kDa ribosomal protein S6 kinase
    cd14178
    Location:409 → 701
    STKc_RSK3_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Ribosomal S6 kinase 3 (also called Ribosomal protein S6 kinase alpha-2 or 90kDa ribosomal protein S6 kinase 2)

  3. XM_038654618.1 → XP_038510546.1  ribosomal protein S6 kinase alpha-2 isoform X5

    UniProtKB/TrEMBL
    A0A8C0PRJ4, A0A8C0Q698, A0A8I3MYD7
    Conserved Domains (2) summary
    cd05582
    Location:47 → 363
    STKc_RSK_N; N-terminal catalytic domain of the Serine/Threonine Kinase, 90 kDa ribosomal protein S6 kinase
    cd14178
    Location:395 → 687
    STKc_RSK3_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Ribosomal S6 kinase 3 (also called Ribosomal protein S6 kinase alpha-2 or 90kDa ribosomal protein S6 kinase 2)

  4. XM_038654616.1 → XP_038510544.1  ribosomal protein S6 kinase alpha-2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0L0T0, A0A8C0MQK0, A0A8I3MP05, A0A8I3MXK3
    Related
    ENSCAFP00845006708.1, ENSCAFT00845008504.1
    Conserved Domains (2) summary
    cd05582
    Location:63 → 379
    STKc_RSK_N; N-terminal catalytic domain of the Serine/Threonine Kinase, 90 kDa ribosomal protein S6 kinase
    cd14178
    Location:411 → 703
    STKc_RSK3_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Ribosomal S6 kinase 3 (also called Ribosomal protein S6 kinase alpha-2 or 90kDa ribosomal protein S6 kinase 2)

  5. XM_038654614.1 → XP_038510542.1  ribosomal protein S6 kinase alpha-2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0RVG8, A0A8I3MV42
    Related
    ENSCAFP00845006728.1, ENSCAFT00845008526.1
    Conserved Domains (2) summary
    cd05582
    Location:52 → 368
    STKc_RSK_N; N-terminal catalytic domain of the Serine/Threonine Kinase, 90 kDa ribosomal protein S6 kinase
    cd14178
    Location:400 → 692
    STKc_RSK3_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Ribosomal S6 kinase 3 (also called Ribosomal protein S6 kinase alpha-2 or 90kDa ribosomal protein S6 kinase 2)

  6. XM_038654619.1 → XP_038510547.1  ribosomal protein S6 kinase alpha-2 isoform X6

    UniProtKB/TrEMBL
    A0A8C0Q698, A0A8I3MYD7
    Conserved Domains (2) summary
    cd05582
    Location:31 → 347
    STKc_RSK_N; N-terminal catalytic domain of the Serine/Threonine Kinase, 90 kDa ribosomal protein S6 kinase
    cd14178
    Location:379 → 671
    STKc_RSK3_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Ribosomal S6 kinase 3 (also called Ribosomal protein S6 kinase alpha-2 or 90kDa ribosomal protein S6 kinase 2)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049261.1 Alternate UMICH_Zoey_3.1

    Range
    54489815..54835148 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038465847.1 → XP_038321775.1  ribosomal protein S6 kinase alpha-2 isoform X2

    Conserved Domains (2) summary
    cd05582
    Location:88 → 404
    STKc_RSK_N; N-terminal catalytic domain of the Serine/Threonine Kinase, 90 kDa ribosomal protein S6 kinase
    cd14178
    Location:436 → 728
    STKc_RSK3_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Ribosomal S6 kinase 3 (also called Ribosomal protein S6 kinase alpha-2 or 90kDa ribosomal protein S6 kinase 2)

  2. XM_038465849.1 → XP_038321777.1  ribosomal protein S6 kinase alpha-2 isoform X4

    Conserved Domains (2) summary
    cd05582
    Location:61 → 377
    STKc_RSK_N; N-terminal catalytic domain of the Serine/Threonine Kinase, 90 kDa ribosomal protein S6 kinase
    cd14178
    Location:409 → 701
    STKc_RSK3_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Ribosomal S6 kinase 3 (also called Ribosomal protein S6 kinase alpha-2 or 90kDa ribosomal protein S6 kinase 2)

  3. XM_038465850.1 → XP_038321778.1  ribosomal protein S6 kinase alpha-2 isoform X5

    Conserved Domains (2) summary
    cd05582
    Location:47 → 363
    STKc_RSK_N; N-terminal catalytic domain of the Serine/Threonine Kinase, 90 kDa ribosomal protein S6 kinase
    cd14178
    Location:395 → 687
    STKc_RSK3_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Ribosomal S6 kinase 3 (also called Ribosomal protein S6 kinase alpha-2 or 90kDa ribosomal protein S6 kinase 2)

  4. XM_038465848.1 → XP_038321776.1  ribosomal protein S6 kinase alpha-2 isoform X3

    Conserved Domains (2) summary
    cd05582
    Location:63 → 379
    STKc_RSK_N; N-terminal catalytic domain of the Serine/Threonine Kinase, 90 kDa ribosomal protein S6 kinase
    cd14178
    Location:411 → 703
    STKc_RSK3_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Ribosomal S6 kinase 3 (also called Ribosomal protein S6 kinase alpha-2 or 90kDa ribosomal protein S6 kinase 2)

  5. XM_038465846.1 → XP_038321774.1  ribosomal protein S6 kinase alpha-2 isoform X1

    Conserved Domains (2) summary
    cd05582
    Location:52 → 368
    STKc_RSK_N; N-terminal catalytic domain of the Serine/Threonine Kinase, 90 kDa ribosomal protein S6 kinase
    cd14178
    Location:400 → 692
    STKc_RSK3_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Ribosomal S6 kinase 3 (also called Ribosomal protein S6 kinase alpha-2 or 90kDa ribosomal protein S6 kinase 2)

  6. XM_038465851.1 → XP_038321779.1  ribosomal protein S6 kinase alpha-2 isoform X6

    Conserved Domains (2) summary
    cd05582
    Location:31 → 347
    STKc_RSK_N; N-terminal catalytic domain of the Serine/Threonine Kinase, 90 kDa ribosomal protein S6 kinase
    cd14178
    Location:379 → 671
    STKc_RSK3_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Ribosomal S6 kinase 3 (also called Ribosomal protein S6 kinase alpha-2 or 90kDa ribosomal protein S6 kinase 2)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049742.1 Alternate UNSW_CanFamBas_1.0

    Range
    54338945..54683764 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038590818.1 → XP_038446746.1  ribosomal protein S6 kinase alpha-2 isoform X2

  2. XM_038590820.1 → XP_038446748.1  ribosomal protein S6 kinase alpha-2 isoform X4

  3. XM_038590821.1 → XP_038446749.1  ribosomal protein S6 kinase alpha-2 isoform X5

  4. XM_038590819.1 → XP_038446747.1  ribosomal protein S6 kinase alpha-2 isoform X3

  5. XM_038590817.1 → XP_038446745.1  ribosomal protein S6 kinase alpha-2 isoform X1

  6. XM_038590822.1 → XP_038446750.1  ribosomal protein S6 kinase alpha-2 isoform X6

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049222.1 Alternate UU_Cfam_GSD_1.0

    Range
    54963546..55308688 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038526526.1 → XP_038382454.1  ribosomal protein S6 kinase alpha-2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0MT56, A0A8P0PSW9, A0A8P0T3S5
    Conserved Domains (2) summary
    cd05582
    Location:88 → 404
    STKc_RSK_N; N-terminal catalytic domain of the Serine/Threonine Kinase, 90 kDa ribosomal protein S6 kinase
    cd14178
    Location:436 → 728
    STKc_RSK3_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Ribosomal S6 kinase 3 (also called Ribosomal protein S6 kinase alpha-2 or 90kDa ribosomal protein S6 kinase 2)

  2. XM_038526528.1 → XP_038382456.1  ribosomal protein S6 kinase alpha-2 isoform X4

    UniProtKB/TrEMBL
    A0A8C0REI3, A0A8P0PC03, A0A8P0PSW9
    Conserved Domains (2) summary
    cd05582
    Location:61 → 377
    STKc_RSK_N; N-terminal catalytic domain of the Serine/Threonine Kinase, 90 kDa ribosomal protein S6 kinase
    cd14178
    Location:409 → 701
    STKc_RSK3_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Ribosomal S6 kinase 3 (also called Ribosomal protein S6 kinase alpha-2 or 90kDa ribosomal protein S6 kinase 2)

  3. XM_038526530.1 → XP_038382458.1  ribosomal protein S6 kinase alpha-2 isoform X5

    UniProtKB/TrEMBL
    A0A8C0PRJ4, A0A8C0Q698, A0A8I3MYD7
    Conserved Domains (2) summary
    cd05582
    Location:47 → 363
    STKc_RSK_N; N-terminal catalytic domain of the Serine/Threonine Kinase, 90 kDa ribosomal protein S6 kinase
    cd14178
    Location:395 → 687
    STKc_RSK3_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Ribosomal S6 kinase 3 (also called Ribosomal protein S6 kinase alpha-2 or 90kDa ribosomal protein S6 kinase 2)

  4. XM_038526527.1 → XP_038382455.1  ribosomal protein S6 kinase alpha-2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0L0T0, A0A8C0MQK0, A0A8I3MP05, A0A8I3MXK3
    Conserved Domains (2) summary
    cd05582
    Location:63 → 379
    STKc_RSK_N; N-terminal catalytic domain of the Serine/Threonine Kinase, 90 kDa ribosomal protein S6 kinase
    cd14178
    Location:411 → 703
    STKc_RSK3_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Ribosomal S6 kinase 3 (also called Ribosomal protein S6 kinase alpha-2 or 90kDa ribosomal protein S6 kinase 2)

  5. XM_038526529.1 → XP_038382457.1  ribosomal protein S6 kinase alpha-2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0RVG8, A0A8I3MV42
    Conserved Domains (2) summary
    cd05582
    Location:52 → 368
    STKc_RSK_N; N-terminal catalytic domain of the Serine/Threonine Kinase, 90 kDa ribosomal protein S6 kinase
    cd14178
    Location:400 → 692
    STKc_RSK3_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Ribosomal S6 kinase 3 (also called Ribosomal protein S6 kinase alpha-2 or 90kDa ribosomal protein S6 kinase 2)

  6. XM_038526531.1 → XP_038382459.1  ribosomal protein S6 kinase alpha-2 isoform X6

    UniProtKB/TrEMBL
    A0A8C0Q698, A0A8I3MYD7
    Conserved Domains (2) summary
    cd05582
    Location:31 → 347
    STKc_RSK_N; N-terminal catalytic domain of the Serine/Threonine Kinase, 90 kDa ribosomal protein S6 kinase
    cd14178
    Location:379 → 671
    STKc_RSK3_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Ribosomal S6 kinase 3 (also called Ribosomal protein S6 kinase alpha-2 or 90kDa ribosomal protein S6 kinase 2)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    55202572..55547248 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014113139.3 → XP_013968614.1  ribosomal protein S6 kinase alpha-2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0MT56, A0A8P0PSW9, A0A8P0T3S5
    Conserved Domains (2) summary
    cd05582
    Location:88 → 404
    STKc_RSK_N; N-terminal catalytic domain of the Serine/Threonine Kinase, 90 kDa ribosomal protein S6 kinase
    cd14178
    Location:436 → 728
    STKc_RSK3_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Ribosomal S6 kinase 3 (also called Ribosomal protein S6 kinase alpha-2 or 90kDa ribosomal protein S6 kinase 2)

  2. XM_014113147.3 → XP_013968622.1  ribosomal protein S6 kinase alpha-2 isoform X4

    UniProtKB/TrEMBL
    A0A8C0REI3, A0A8P0PC03, A0A8P0PSW9
    Conserved Domains (2) summary
    cd05582
    Location:61 → 377
    STKc_RSK_N; N-terminal catalytic domain of the Serine/Threonine Kinase, 90 kDa ribosomal protein S6 kinase
    cd14178
    Location:409 → 701
    STKc_RSK3_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Ribosomal S6 kinase 3 (also called Ribosomal protein S6 kinase alpha-2 or 90kDa ribosomal protein S6 kinase 2)

  3. XM_022418896.2 → XP_022274604.1  ribosomal protein S6 kinase alpha-2 isoform X5

    UniProtKB/TrEMBL
    A0A8C0PRJ4, A0A8C0Q698, A0A8I3MYD7
    Conserved Domains (2) summary
    cd05582
    Location:47 → 363
    STKc_RSK_N; N-terminal catalytic domain of the Serine/Threonine Kinase, 90 kDa ribosomal protein S6 kinase
    cd14178
    Location:395 → 687
    STKc_RSK3_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Ribosomal S6 kinase 3 (also called Ribosomal protein S6 kinase alpha-2 or 90kDa ribosomal protein S6 kinase 2)

  4. XM_850175.6 → XP_855268.5  ribosomal protein S6 kinase alpha-2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0L0T0, A0A8C0MQK0, A0A8I3MP05, A0A8I3MXK3
    Conserved Domains (2) summary
    cd05582
    Location:63 → 379
    STKc_RSK_N; N-terminal catalytic domain of the Serine/Threonine Kinase, 90 kDa ribosomal protein S6 kinase
    cd14178
    Location:411 → 703
    STKc_RSK3_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Ribosomal S6 kinase 3 (also called Ribosomal protein S6 kinase alpha-2 or 90kDa ribosomal protein S6 kinase 2)

  5. XM_014113137.3 → XP_013968612.1  ribosomal protein S6 kinase alpha-2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0RVG8, A0A8I3MV42
    Conserved Domains (2) summary
    cd05582
    Location:52 → 368
    STKc_RSK_N; N-terminal catalytic domain of the Serine/Threonine Kinase, 90 kDa ribosomal protein S6 kinase
    cd14178
    Location:400 → 692
    STKc_RSK3_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Ribosomal S6 kinase 3 (also called Ribosomal protein S6 kinase alpha-2 or 90kDa ribosomal protein S6 kinase 2)

  6. XM_022418900.2 → XP_022274608.1  ribosomal protein S6 kinase alpha-2 isoform X6

    UniProtKB/TrEMBL
    A0A8C0Q698, A0A8I3MYD7
    Conserved Domains (2) summary
    cd05582
    Location:31 → 347
    STKc_RSK_N; N-terminal catalytic domain of the Serine/Threonine Kinase, 90 kDa ribosomal protein S6 kinase
    cd14178
    Location:379 → 671
    STKc_RSK3_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Ribosomal S6 kinase 3 (also called Ribosomal protein S6 kinase alpha-2 or 90kDa ribosomal protein S6 kinase 2)
Nucleotide Protein
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