CEACAM1 CEA cell adhesion molecule 1 [Canis lupus familiaris (dog)] - Gene

Summary

Gene symbol: CEACAM1
Gene description: CEA cell adhesion molecule 1
See related: Ensembl:ENSCAFG00845000573
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
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Genomic context

Location:: chromosome: 1

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	1	NC_051805.1 (112464630..112529985)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	1	NC_006583.4 (111327263..111342206)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	1	NC_049222.1 (112587794..112644821)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	1	NC_049261.1 (112027612..112084452)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	1	NC_049742.1 (111661182..111718360)

Chromosome 1 - NC_051805.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

CEACAM1 and CEACAM28 are the first paired immune receptors identified within the CEA gene family, which are expressed on T cells and are most likely involved in the fine-tuning of T cell responses.
Title: Species-specific evolution of immune receptor tyrosine based activation motif-containing CEACAM1-related immune receptors in the dog.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein tyrosine kinase binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of immune system process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in signal transduction	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cell surface	IEA Inferred from Electronic Annotation more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: carcinoembryonic antigen-related cell adhesion molecule 1

Names: carcinoembryonic antigen related cell adhesion molecule 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001097557.1 → NP_001091026.1 carcinoembryonic antigen-related cell adhesion molecule 1 precursor

See identical proteins and their annotated locations for NP_001091026.1

Status: PROVISIONAL

Source sequence(s)

DQ975208

UniProtKB/TrEMBL

A0A8I3ME18, A0A8P0SWD1, Q004B2

Conserved Domains (3) summary

cd05740
Location:146 → 234

IgI_hCEACAM_2_4_6_like; Immunoglobulin (Ig)-like domain of human carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM) domains 2, 4, and 6, and similar domains

cd05774
Location:36 → 140

IgV_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)

cd20948
Location:243 → 318

IgC2_CEACAM5-like; Fifth immunoglobulin (Ig)-like domain of the carcinoembryonic antigen (CEA) related cell adhesion molecule 5 (CEACAM5) and similar domains; member of the C2-set IgSF domains

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051805.1 Reference ROS_Cfam_1.0

Range

112464630..112529985

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038653569.1 → XP_038509497.1 carcinoembryonic antigen-related cell adhesion molecule 1 isoform X4

UniProtKB/TrEMBL

A0A8C0KMF3, A0A8C0SU19, E2RRT0, Q004B1

Conserved Domains (3) summary

cd05740
Location:146 → 234

IgI_hCEACAM_2_4_6_like; Immunoglobulin (Ig)-like domain of human carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM) domains 2, 4, and 6, and similar domains

cd05774
Location:36 → 140

IgV_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)

cd20948
Location:243 → 318

IgC2_CEACAM5-like; Fifth immunoglobulin (Ig)-like domain of the carcinoembryonic antigen (CEA) related cell adhesion molecule 5 (CEACAM5) and similar domains; member of the C2-set IgSF domains
XM_038653567.1 → XP_038509495.1 carcinoembryonic antigen-related cell adhesion molecule 1 isoform X2

UniProtKB/TrEMBL

A0A8I3MAY8

Related

ENSCAFP00845000711.1, ENSCAFT00845000942.1

Conserved Domains (3) summary

cd05740
Location:127 → 215

IgI_hCEACAM_2_4_6_like; Immunoglobulin (Ig)-like domain of human carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM) domains 2, 4, and 6, and similar domains

cd05774
Location:17 → 121

IgV_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)

cd20948
Location:224 → 299

IgC2_CEACAM5-like; Fifth immunoglobulin (Ig)-like domain of the carcinoembryonic antigen (CEA) related cell adhesion molecule 5 (CEACAM5) and similar domains; member of the C2-set IgSF domains
XM_038653566.1 → XP_038509494.1 carcinoembryonic antigen-related cell adhesion molecule 1 isoform X1

UniProtKB/TrEMBL

A0A8I3ME18, A0A8P0SWD1, Q004B2

Related

ENSCAFP00845000854.1, ENSCAFT00845001131.1

Conserved Domains (3) summary

cd05740
Location:146 → 234

IgI_hCEACAM_2_4_6_like; Immunoglobulin (Ig)-like domain of human carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM) domains 2, 4, and 6, and similar domains

cd05774
Location:36 → 140

IgV_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)

cd20948
Location:243 → 318

IgC2_CEACAM5-like; Fifth immunoglobulin (Ig)-like domain of the carcinoembryonic antigen (CEA) related cell adhesion molecule 5 (CEACAM5) and similar domains; member of the C2-set IgSF domains
XM_038653568.1 → XP_038509496.1 carcinoembryonic antigen-related cell adhesion molecule 1 isoform X3

UniProtKB/TrEMBL

A0A8C0KMF3, A0A8C0SU19, E2RRT0, Q004B1

Related

ENSCAFP00845000738.1, ENSCAFT00845000974.1

Conserved Domains (3) summary

cd05740
Location:146 → 234

IgI_hCEACAM_2_4_6_like; Immunoglobulin (Ig)-like domain of human carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM) domains 2, 4, and 6, and similar domains

cd05774
Location:36 → 140

IgV_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)

cd20948
Location:243 → 318

IgC2_CEACAM5-like; Fifth immunoglobulin (Ig)-like domain of the carcinoembryonic antigen (CEA) related cell adhesion molecule 5 (CEACAM5) and similar domains; member of the C2-set IgSF domains