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MATK megakaryocyte-associated tyrosine kinase [ Canis lupus familiaris (dog) ]

Gene ID: 611999, updated on 5-Mar-2024

Summary

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Official Symbol
MATKprovided by VGNC
Official Full Name
megakaryocyte-associated tyrosine kinaseprovided by VGNC
Primary source
VGNC:VGNC:43039
See related
Ensembl:ENSCAFG00845007724
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 20
Exon count:
16
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (56357401..56364179)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (55422757..55429545)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (56094009..56100857)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (55413344..55420706)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (55895262..55902025)

Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene ATCAY kinesin light chain interacting caytaxin Neighboring gene microRNA mir-8802 Neighboring gene zinc finger RNA binding protein 2 Neighboring gene mitochondrial ribosomal protein L54 Neighboring gene retina and anterior neural fold homeobox 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
megakaryocyte-associated tyrosine-protein kinase
XP_005633123.1
XP_005633125.1
XP_005633127.1
XP_022262934.1
XP_022262936.1
XP_038285041.1
XP_038285042.1
XP_038285043.1
XP_038285044.1
XP_038285045.1
XP_038285046.1
XP_038285047.1
XP_038285048.1
XP_038311405.1
XP_038311407.1
XP_038360617.1
XP_038360618.1
XP_038360619.1
XP_038360620.1
XP_038360621.1
XP_038360622.1
XP_038360623.1
XP_038423728.1
XP_038423729.1
XP_038423730.1
XP_038423731.1
XP_038423732.1
XP_038423733.1
XP_038423734.1
XP_038423735.1
XP_038487838.1
XP_038487839.1
XP_038487840.1
XP_038487841.1
XP_038487842.1
XP_038487843.1
XP_038487844.1
XP_038487845.1
XP_038487846.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051824.1 Reference ROS_Cfam_1.0

    Range
    56357401..56364179
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038429120.1 → XP_038285048.1  megakaryocyte-associated tyrosine-protein kinase isoform X4

    UniProtKB/TrEMBL
    A0A8C0M8Z5, A0A8I3N394, A0A8I3N3Q4
    Conserved Domains (3) summary
    cd09937
    Location:77 → 174
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11811
    Location:9 → 67
    SH3_CHK; Src Homology 3 domain of CSK homologous kinase
    cd05083
    Location:187 → 440
    PTKc_Chk; Catalytic domain of the Protein Tyrosine Kinase, Csk homologous kinase

  2. XM_038429116.1 → XP_038285044.1  megakaryocyte-associated tyrosine-protein kinase isoform X3

    UniProtKB/TrEMBL
    A0A8C0M8Z5, A0A8I3N394
    Conserved Domains (3) summary
    cd09937
    Location:96 → 193
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11811
    Location:28 → 86
    SH3_CHK; Src Homology 3 domain of CSK homologous kinase
    cl21453
    Location:206 → 455
    PKc_like; Protein Kinases, catalytic domain

  3. XM_038429115.1 → XP_038285043.1  megakaryocyte-associated tyrosine-protein kinase isoform X2

    UniProtKB/TrEMBL
    A0A8C0M8Z5, A0A8I3N394
    Conserved Domains (3) summary
    cd09937
    Location:96 → 193
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11811
    Location:28 → 86
    SH3_CHK; Src Homology 3 domain of CSK homologous kinase
    cl21453
    Location:206 → 456
    PKc_like; Protein Kinases, catalytic domain

  4. XM_038429117.1 → XP_038285045.1  megakaryocyte-associated tyrosine-protein kinase isoform X4

    UniProtKB/TrEMBL
    A0A8C0M8Z5, A0A8I3N394, A0A8I3N3Q4
    Conserved Domains (3) summary
    cd09937
    Location:77 → 174
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11811
    Location:9 → 67
    SH3_CHK; Src Homology 3 domain of CSK homologous kinase
    cd05083
    Location:187 → 440
    PTKc_Chk; Catalytic domain of the Protein Tyrosine Kinase, Csk homologous kinase

  5. XM_038429113.1 → XP_038285041.1  megakaryocyte-associated tyrosine-protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A8C0M8Z5, A0A8C0MCJ4, A0A8I3N394
    Conserved Domains (3) summary
    cd09937
    Location:96 → 193
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11811
    Location:28 → 86
    SH3_CHK; Src Homology 3 domain of CSK homologous kinase
    cd05083
    Location:206 → 459
    PTKc_Chk; Catalytic domain of the Protein Tyrosine Kinase, Csk homologous kinase

  6. XM_038429119.1 → XP_038285047.1  megakaryocyte-associated tyrosine-protein kinase isoform X4

    UniProtKB/TrEMBL
    A0A8C0M8Z5, A0A8I3N394, A0A8I3N3Q4
    Related
    ENSCAFP00845010681.1, ENSCAFT00845013758.1
    Conserved Domains (3) summary
    cd09937
    Location:77 → 174
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11811
    Location:9 → 67
    SH3_CHK; Src Homology 3 domain of CSK homologous kinase
    cd05083
    Location:187 → 440
    PTKc_Chk; Catalytic domain of the Protein Tyrosine Kinase, Csk homologous kinase

  7. XM_038429118.1 → XP_038285046.1  megakaryocyte-associated tyrosine-protein kinase isoform X4

    UniProtKB/TrEMBL
    A0A8C0M8Z5, A0A8I3N394, A0A8I3N3Q4
    Conserved Domains (3) summary
    cd09937
    Location:77 → 174
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11811
    Location:9 → 67
    SH3_CHK; Src Homology 3 domain of CSK homologous kinase
    cd05083
    Location:187 → 440
    PTKc_Chk; Catalytic domain of the Protein Tyrosine Kinase, Csk homologous kinase

  8. XM_038429114.1 → XP_038285042.1  megakaryocyte-associated tyrosine-protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A8C0M8Z5, A0A8C0MCJ4, A0A8I3N394
    Conserved Domains (3) summary
    cd09937
    Location:96 → 193
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11811
    Location:28 → 86
    SH3_CHK; Src Homology 3 domain of CSK homologous kinase
    cd05083
    Location:206 → 459
    PTKc_Chk; Catalytic domain of the Protein Tyrosine Kinase, Csk homologous kinase

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049280.1 Alternate UMICH_Zoey_3.1

    Range
    55413344..55420706
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038504695.1 → XP_038360623.1  megakaryocyte-associated tyrosine-protein kinase isoform X8

  2. XM_038504690.1 → XP_038360618.1  megakaryocyte-associated tyrosine-protein kinase isoform X6

  3. XM_038504691.1 → XP_038360619.1  megakaryocyte-associated tyrosine-protein kinase isoform X7

  4. XM_038504692.1 → XP_038360620.1  megakaryocyte-associated tyrosine-protein kinase isoform X8

  5. XM_038504689.1 → XP_038360617.1  megakaryocyte-associated tyrosine-protein kinase isoform X5

  6. XM_038504694.1 → XP_038360622.1  megakaryocyte-associated tyrosine-protein kinase isoform X8

  7. XM_038504693.1 → XP_038360621.1  megakaryocyte-associated tyrosine-protein kinase isoform X8

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

    Range
    55895262..55902025
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038631918.1 → XP_038487846.1  megakaryocyte-associated tyrosine-protein kinase isoform X4

    Conserved Domains (3) summary
    cd09937
    Location:77 → 174
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11811
    Location:9 → 67
    SH3_CHK; Src Homology 3 domain of CSK homologous kinase
    cd05083
    Location:187 → 440
    PTKc_Chk; Catalytic domain of the Protein Tyrosine Kinase, Csk homologous kinase

  2. XM_038631913.1 → XP_038487841.1  megakaryocyte-associated tyrosine-protein kinase isoform X3

    Conserved Domains (3) summary
    cd09937
    Location:96 → 193
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11811
    Location:28 → 86
    SH3_CHK; Src Homology 3 domain of CSK homologous kinase
    cl21453
    Location:206 → 455
    PKc_like; Protein Kinases, catalytic domain

  3. XM_038631912.1 → XP_038487840.1  megakaryocyte-associated tyrosine-protein kinase isoform X2

    Conserved Domains (3) summary
    cd09937
    Location:96 → 193
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11811
    Location:28 → 86
    SH3_CHK; Src Homology 3 domain of CSK homologous kinase
    cl21453
    Location:206 → 456
    PKc_like; Protein Kinases, catalytic domain

  4. XM_038631914.1 → XP_038487842.1  megakaryocyte-associated tyrosine-protein kinase isoform X4

    Conserved Domains (3) summary
    cd09937
    Location:77 → 174
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11811
    Location:9 → 67
    SH3_CHK; Src Homology 3 domain of CSK homologous kinase
    cd05083
    Location:187 → 440
    PTKc_Chk; Catalytic domain of the Protein Tyrosine Kinase, Csk homologous kinase

  5. XM_038631910.1 → XP_038487838.1  megakaryocyte-associated tyrosine-protein kinase isoform X1

    Conserved Domains (3) summary
    cd09937
    Location:96 → 193
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11811
    Location:28 → 86
    SH3_CHK; Src Homology 3 domain of CSK homologous kinase
    cd05083
    Location:206 → 459
    PTKc_Chk; Catalytic domain of the Protein Tyrosine Kinase, Csk homologous kinase

  6. XM_038631917.1 → XP_038487845.1  megakaryocyte-associated tyrosine-protein kinase isoform X4

    Conserved Domains (3) summary
    cd09937
    Location:77 → 174
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11811
    Location:9 → 67
    SH3_CHK; Src Homology 3 domain of CSK homologous kinase
    cd05083
    Location:187 → 440
    PTKc_Chk; Catalytic domain of the Protein Tyrosine Kinase, Csk homologous kinase

  7. XM_038631916.1 → XP_038487844.1  megakaryocyte-associated tyrosine-protein kinase isoform X4

    Conserved Domains (3) summary
    cd09937
    Location:77 → 174
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11811
    Location:9 → 67
    SH3_CHK; Src Homology 3 domain of CSK homologous kinase
    cd05083
    Location:187 → 440
    PTKc_Chk; Catalytic domain of the Protein Tyrosine Kinase, Csk homologous kinase

  8. XM_038631911.1 → XP_038487839.1  megakaryocyte-associated tyrosine-protein kinase isoform X1

    Conserved Domains (3) summary
    cd09937
    Location:96 → 193
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11811
    Location:28 → 86
    SH3_CHK; Src Homology 3 domain of CSK homologous kinase
    cd05083
    Location:206 → 459
    PTKc_Chk; Catalytic domain of the Protein Tyrosine Kinase, Csk homologous kinase

  9. XM_038631915.1 → XP_038487843.1  megakaryocyte-associated tyrosine-protein kinase isoform X4

    Conserved Domains (3) summary
    cd09937
    Location:77 → 174
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11811
    Location:9 → 67
    SH3_CHK; Src Homology 3 domain of CSK homologous kinase
    cd05083
    Location:187 → 440
    PTKc_Chk; Catalytic domain of the Protein Tyrosine Kinase, Csk homologous kinase

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

    Range
    56094009..56100857
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038567807.1 → XP_038423735.1  megakaryocyte-associated tyrosine-protein kinase isoform X4

    UniProtKB/TrEMBL
    A0A8P0NKD1, A0A8P0T2H7
    Conserved Domains (3) summary
    cd09937
    Location:77 → 174
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11811
    Location:9 → 67
    SH3_CHK; Src Homology 3 domain of CSK homologous kinase
    cd05083
    Location:187 → 440
    PTKc_Chk; Catalytic domain of the Protein Tyrosine Kinase, Csk homologous kinase

  2. XM_038567803.1 → XP_038423731.1  megakaryocyte-associated tyrosine-protein kinase isoform X3

    UniProtKB/TrEMBL
    A0A8P0NKD1

  3. XM_038567802.1 → XP_038423730.1  megakaryocyte-associated tyrosine-protein kinase isoform X2

    UniProtKB/TrEMBL
    A0A8P0NKD1
    Conserved Domains (3) summary
    cd09937
    Location:96 → 193
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11811
    Location:28 → 86
    SH3_CHK; Src Homology 3 domain of CSK homologous kinase
    cl21453
    Location:206 → 456
    PKc_like; Protein Kinases, catalytic domain

  4. XM_038567805.1 → XP_038423733.1  megakaryocyte-associated tyrosine-protein kinase isoform X4

    UniProtKB/TrEMBL
    A0A8P0NKD1, A0A8P0T2H7
    Conserved Domains (3) summary
    cd09937
    Location:77 → 174
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11811
    Location:9 → 67
    SH3_CHK; Src Homology 3 domain of CSK homologous kinase
    cd05083
    Location:187 → 440
    PTKc_Chk; Catalytic domain of the Protein Tyrosine Kinase, Csk homologous kinase

  5. XM_038567800.1 → XP_038423728.1  megakaryocyte-associated tyrosine-protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A8C0L113, A0A8P0NKD1, A0A8P0NSA7

  6. XM_038567806.1 → XP_038423734.1  megakaryocyte-associated tyrosine-protein kinase isoform X4

    UniProtKB/TrEMBL
    A0A8P0NKD1, A0A8P0T2H7
    Conserved Domains (3) summary
    cd09937
    Location:77 → 174
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11811
    Location:9 → 67
    SH3_CHK; Src Homology 3 domain of CSK homologous kinase
    cd05083
    Location:187 → 440
    PTKc_Chk; Catalytic domain of the Protein Tyrosine Kinase, Csk homologous kinase

  7. XM_038567801.1 → XP_038423729.1  megakaryocyte-associated tyrosine-protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A8C0L113, A0A8P0NKD1, A0A8P0NSA7

  8. XM_038567804.1 → XP_038423732.1  megakaryocyte-associated tyrosine-protein kinase isoform X4

    UniProtKB/TrEMBL
    A0A8P0NKD1, A0A8P0T2H7
    Conserved Domains (3) summary
    cd09937
    Location:77 → 174
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11811
    Location:9 → 67
    SH3_CHK; Src Homology 3 domain of CSK homologous kinase
    cd05083
    Location:187 → 440
    PTKc_Chk; Catalytic domain of the Protein Tyrosine Kinase, Csk homologous kinase

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    55422757..55429545
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005633070.4 → XP_005633127.1  megakaryocyte-associated tyrosine-protein kinase isoform X4

    See identical proteins and their annotated locations for XP_005633127.1

    UniProtKB/TrEMBL
    A0A8P0NKD1, A0A8P0T2H7
    Conserved Domains (3) summary
    cd09937
    Location:77 → 174
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11811
    Location:9 → 67
    SH3_CHK; Src Homology 3 domain of CSK homologous kinase
    cd05083
    Location:187 → 440
    PTKc_Chk; Catalytic domain of the Protein Tyrosine Kinase, Csk homologous kinase

  2. XM_022407226.2 → XP_022262934.1  megakaryocyte-associated tyrosine-protein kinase isoform X3

    UniProtKB/TrEMBL
    A0A8P0NKD1
    Conserved Domains (3) summary
    cd09937
    Location:96 → 193
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11811
    Location:28 → 86
    SH3_CHK; Src Homology 3 domain of CSK homologous kinase
    cl21453
    Location:206 → 455
    PKc_like; Protein Kinases, catalytic domain

  3. XM_038455477.1 → XP_038311405.1  megakaryocyte-associated tyrosine-protein kinase isoform X2

    UniProtKB/TrEMBL
    A0A8P0NKD1
    Conserved Domains (3) summary
    cd09937
    Location:96 → 193
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11811
    Location:28 → 86
    SH3_CHK; Src Homology 3 domain of CSK homologous kinase
    cl21453
    Location:206 → 456
    PKc_like; Protein Kinases, catalytic domain

  4. XM_022407228.2 → XP_022262936.1  megakaryocyte-associated tyrosine-protein kinase isoform X4

    UniProtKB/TrEMBL
    A0A8P0NKD1, A0A8P0T2H7
    Conserved Domains (3) summary
    cd09937
    Location:77 → 174
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11811
    Location:9 → 67
    SH3_CHK; Src Homology 3 domain of CSK homologous kinase
    cd05083
    Location:187 → 440
    PTKc_Chk; Catalytic domain of the Protein Tyrosine Kinase, Csk homologous kinase

  5. XM_005633066.4 → XP_005633123.1  megakaryocyte-associated tyrosine-protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A8C0L113, A0A8P0NKD1, A0A8P0NSA7
    Conserved Domains (3) summary
    cd09937
    Location:96 → 193
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11811
    Location:28 → 86
    SH3_CHK; Src Homology 3 domain of CSK homologous kinase
    cd05083
    Location:206 → 459
    PTKc_Chk; Catalytic domain of the Protein Tyrosine Kinase, Csk homologous kinase

  6. XM_005633068.4 → XP_005633125.1  megakaryocyte-associated tyrosine-protein kinase isoform X4

    See identical proteins and their annotated locations for XP_005633125.1

    UniProtKB/TrEMBL
    A0A8P0NKD1, A0A8P0T2H7
    Conserved Domains (3) summary
    cd09937
    Location:77 → 174
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11811
    Location:9 → 67
    SH3_CHK; Src Homology 3 domain of CSK homologous kinase
    cd05083
    Location:187 → 440
    PTKc_Chk; Catalytic domain of the Protein Tyrosine Kinase, Csk homologous kinase

  7. XM_038455479.1 → XP_038311407.1  megakaryocyte-associated tyrosine-protein kinase isoform X4

    UniProtKB/TrEMBL
    A0A8P0NKD1, A0A8P0T2H7
    Conserved Domains (3) summary
    cd09937
    Location:77 → 174
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11811
    Location:9 → 67
    SH3_CHK; Src Homology 3 domain of CSK homologous kinase
    cd05083
    Location:187 → 440
    PTKc_Chk; Catalytic domain of the Protein Tyrosine Kinase, Csk homologous kinase
Nucleotide Protein
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