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GNAI3 G protein subunit alpha i3 [ Canis lupus familiaris (dog) ]

Gene ID: 611810, updated on 5-Mar-2024

Summary

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Official Symbol
GNAI3provided by VGNC
Official Full Name
G protein subunit alpha i3provided by VGNC
Primary source
VGNC:VGNC:41303
See related
Ensembl:ENSCAFG00845002724
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 6
Exon count:
10
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 6 NC_051810.1 (42606591..42646183, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 6 NC_006588.4 (45050635..45090449, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 6 NC_049227.1 (42732429..42771713, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 6 NC_049266.1 (42339208..42379010, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 6 NC_049747.1 (42297245..42336814, complement)

Chromosome 6 - NC_051810.1Genomic Context describing neighboring genes Neighboring gene G protein subunit alpha transducin 2 Neighboring gene microRNA mir-197 Neighboring gene G protein-coupled receptor 61 Neighboring gene uncharacterized LOC102154999

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Targeted G-protein inhibition as a novel approach to decrease vagal atrial fibrillation by selective parasympathetic attenuation. Aistrup GL, et al. Cardiovasc Res, 2009 Aug 1. PMID 19457892, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Inhibition of Galpha(i) interactions in the posterior left atrium would modify the substrate for vagal atrial fibrillation.
    Title: Targeted G-protein inhibition as a novel approach to decrease vagal atrial fibrillation by selective parasympathetic attenuation.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables G-protein beta/gamma-subunit complex binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in adenylate cyclase-modulating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of heterotrimeric G-protein complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
guanine nucleotide-binding protein G(k) subunit alpha; guanine nucleotide-binding protein G(i) subunit alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051810.1 Reference ROS_Cfam_1.0

    Range
    42606591..42646183 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038669872.1 → XP_038525800.1  guanine nucleotide-binding protein G(i) subunit alpha isoform X1

    UniProtKB/TrEMBL
    A0A8C0KAE5, A0A8C0RJE5, A0A8I3RSE4
    Related
    ENSCAFP00845003871.1, ENSCAFT00845004840.1
    Conserved Domains (1) summary
    cd00066
    Location:34 → 348
    G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)

  2. XM_038669873.1 → XP_038525801.1  guanine nucleotide-binding protein G(i) subunit alpha isoform X2

    Conserved Domains (1) summary
    cd00066
    Location:1 → 296
    G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049266.1 Alternate UMICH_Zoey_3.1

    Range
    42339208..42379010 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038479792.1 → XP_038335720.1  guanine nucleotide-binding protein G(i) subunit alpha isoform X1

    Conserved Domains (1) summary
    cd00066
    Location:34 → 348
    G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)

  2. XM_038479793.1 → XP_038335721.1  guanine nucleotide-binding protein G(i) subunit alpha isoform X2

    Conserved Domains (1) summary
    cd00066
    Location:1 → 296
    G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049747.1 Alternate UNSW_CanFamBas_1.0

    Range
    42297245..42336814 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038605209.1 → XP_038461137.1  guanine nucleotide-binding protein G(i) subunit alpha isoform X1

    Conserved Domains (1) summary
    cd00066
    Location:34 → 348
    G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)

  2. XM_038605210.1 → XP_038461138.1  guanine nucleotide-binding protein G(i) subunit alpha isoform X2

    Conserved Domains (1) summary
    cd00066
    Location:1 → 296
    G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049227.1 Alternate UU_Cfam_GSD_1.0

    Range
    42732429..42771713 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038541067.1 → XP_038396995.1  guanine nucleotide-binding protein G(i) subunit alpha isoform X1

    UniProtKB/TrEMBL
    A0A8C0KAE5, A0A8C0RJE5, A0A8I3RSE4
    Conserved Domains (1) summary
    cd00066
    Location:34 → 348
    G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)

  2. XM_038541068.1 → XP_038396996.1  guanine nucleotide-binding protein G(i) subunit alpha isoform X2

    Conserved Domains (1) summary
    cd00066
    Location:1 → 296
    G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006588.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    45050635..45090449 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_849521.7 → XP_854614.3  guanine nucleotide-binding protein G(i) subunit alpha isoform X1

    UniProtKB/TrEMBL
    A0A8C0KAE5, A0A8C0RJE5, A0A8I3RSE4
    Conserved Domains (1) summary
    cd00066
    Location:34 → 348
    G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)

  2. XM_038552320.1 → XP_038408248.1  guanine nucleotide-binding protein G(i) subunit alpha isoform X2

    Conserved Domains (1) summary
    cd00066
    Location:1 → 296
    G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)
Nucleotide Protein
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