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CSF1 colony stimulating factor 1 [ Canis lupus familiaris (dog) ]

Gene ID: 611795, updated on 5-Mar-2024

Summary

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Official Symbol
CSF1provided by VGNC
Official Full Name
colony stimulating factor 1provided by VGNC
Primary source
VGNC:VGNC:39652
See related
Ensembl:ENSCAFG00845002371
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 6
Exon count:
12
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 6 NC_051810.1 (42360013..42379162, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 6 NC_006588.4 (44804295..44823439, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 6 NC_049227.1 (42485555..42505704, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 6 NC_049266.1 (42092785..42111910, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 6 NC_049747.1 (42050361..42070486, complement)

Chromosome 6 - NC_051810.1Genomic Context describing neighboring genes Neighboring gene adenosylhomocysteinase like 1 Neighboring gene uncharacterized LOC119872347 Neighboring gene uncharacterized LOC102153976 Neighboring gene uncharacterized LOC111096347

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in osteoclast differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of macrophage differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
macrophage colony-stimulating factor 1
XP_013970230.1
XP_013970232.1
XP_038335702.1
XP_038335703.1
XP_038335704.1
XP_038335705.1
XP_038335706.1
XP_038335707.1
XP_038396980.1
XP_038396981.1
XP_038396982.1
XP_038396983.1
XP_038396984.1
XP_038396985.1
XP_038396986.1
XP_038408015.1
XP_038408025.1
XP_038408030.1
XP_038408055.1
XP_038461114.1
XP_038461115.1
XP_038461116.1
XP_038461117.1
XP_038461118.1
XP_038461120.1
XP_038461121.1
XP_038461122.1
XP_038525782.1
XP_038525783.1
XP_038525784.1
XP_038525785.1
XP_038525786.1
XP_038525787.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051810.1 Reference ROS_Cfam_1.0

    Range
    42360013..42379162 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038669859.1 → XP_038525787.1  macrophage colony-stimulating factor 1 isoform X3

    Conserved Domains (1) summary
    pfam05337
    Location:41 → 180
    CSF-1; Macrophage colony stimulating factor-1 (CSF-1)

  2. XM_038669855.1 → XP_038525783.1  macrophage colony-stimulating factor 1 isoform X2

    UniProtKB/TrEMBL
    A0A8I3MIU4, A0A8I3MKU0, A0A8P0SNW2
    Related
    ENSCAFP00845003348.1, ENSCAFT00845004189.1
    Conserved Domains (2) summary
    PHA03307
    Location:194 → 398
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam05337
    Location:41 → 180
    CSF-1; Macrophage colony stimulating factor-1 (CSF-1)

  3. XM_038669856.1 → XP_038525784.1  macrophage colony-stimulating factor 1 isoform X2

    UniProtKB/TrEMBL
    A0A8I3MIU4, A0A8I3MKU0, A0A8P0SNW2
    Conserved Domains (2) summary
    PHA03307
    Location:194 → 398
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam05337
    Location:41 → 180
    CSF-1; Macrophage colony stimulating factor-1 (CSF-1)

  4. XM_038669854.1 → XP_038525782.1  macrophage colony-stimulating factor 1 isoform X1

    UniProtKB/TrEMBL
    A0A8I3MIU4
    Related
    ENSCAFP00845003359.1, ENSCAFT00845004202.1
    Conserved Domains (2) summary
    PHA03247
    Location:195 → 557
    PHA03247; large tegument protein UL36; Provisional
    pfam05337
    Location:41 → 180
    CSF-1; Macrophage colony stimulating factor-1 (CSF-1)

  5. XM_038669857.1 → XP_038525785.1  macrophage colony-stimulating factor 1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0YYA0
    Conserved Domains (2) summary
    PHA03247
    Location:188 → 550
    PHA03247; large tegument protein UL36; Provisional
    pfam05337
    Location:34 → 173
    CSF-1; Macrophage colony stimulating factor-1 (CSF-1)

  6. XM_038669858.1 → XP_038525786.1  macrophage colony-stimulating factor 1 isoform X5

    UniProtKB/TrEMBL
    A0A8P0NM07
    Conserved Domains (2) summary
    PHA03247
    Location:179 → 541
    PHA03247; large tegument protein UL36; Provisional
    pfam05337
    Location:25 → 164
    CSF-1; Macrophage colony stimulating factor-1 (CSF-1)

RNA

  1. XR_005428731.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049266.1 Alternate UMICH_Zoey_3.1

    Range
    42092785..42111910 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038479779.1 → XP_038335707.1  macrophage colony-stimulating factor 1 isoform X3

    Conserved Domains (1) summary
    pfam05337
    Location:41 → 180
    CSF-1; Macrophage colony stimulating factor-1 (CSF-1)

  2. XM_038479775.1 → XP_038335703.1  macrophage colony-stimulating factor 1 isoform X2

    Conserved Domains (2) summary
    PHA03307
    Location:194 → 398
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam05337
    Location:41 → 180
    CSF-1; Macrophage colony stimulating factor-1 (CSF-1)

  3. XM_038479776.1 → XP_038335704.1  macrophage colony-stimulating factor 1 isoform X2

    Conserved Domains (2) summary
    PHA03307
    Location:194 → 398
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam05337
    Location:41 → 180
    CSF-1; Macrophage colony stimulating factor-1 (CSF-1)

  4. XM_038479774.1 → XP_038335702.1  macrophage colony-stimulating factor 1 isoform X1

    Conserved Domains (2) summary
    PHA03247
    Location:195 → 557
    PHA03247; large tegument protein UL36; Provisional
    pfam05337
    Location:41 → 180
    CSF-1; Macrophage colony stimulating factor-1 (CSF-1)

  5. XM_038479777.1 → XP_038335705.1  macrophage colony-stimulating factor 1 isoform X4

    Conserved Domains (2) summary
    PHA03247
    Location:188 → 550
    PHA03247; large tegument protein UL36; Provisional
    pfam05337
    Location:34 → 173
    CSF-1; Macrophage colony stimulating factor-1 (CSF-1)

  6. XM_038479778.1 → XP_038335706.1  macrophage colony-stimulating factor 1 isoform X5

    Conserved Domains (2) summary
    PHA03247
    Location:179 → 541
    PHA03247; large tegument protein UL36; Provisional
    pfam05337
    Location:25 → 164
    CSF-1; Macrophage colony stimulating factor-1 (CSF-1)

RNA

  1. XR_005327104.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049747.1 Alternate UNSW_CanFamBas_1.0

    Range
    42050361..42070486 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038605187.1 → XP_038461115.1  macrophage colony-stimulating factor 1 isoform X6

  2. XM_038605194.1 → XP_038461122.1  macrophage colony-stimulating factor 1 isoform X8

  3. XM_038605188.1 → XP_038461116.1  macrophage colony-stimulating factor 1 isoform X6

  4. XM_038605193.1 → XP_038461121.1  macrophage colony-stimulating factor 1 isoform X7

  5. XM_038605186.1 → XP_038461114.1  macrophage colony-stimulating factor 1 isoform X4

    Conserved Domains (2) summary
    PHA03247
    Location:188 → 550
    PHA03247; large tegument protein UL36; Provisional
    pfam05337
    Location:34 → 173
    CSF-1; Macrophage colony stimulating factor-1 (CSF-1)

  6. XM_038605192.1 → XP_038461120.1  macrophage colony-stimulating factor 1 isoform X5

    Conserved Domains (2) summary
    PHA03247
    Location:179 → 541
    PHA03247; large tegument protein UL36; Provisional
    pfam05337
    Location:25 → 164
    CSF-1; Macrophage colony stimulating factor-1 (CSF-1)

  7. XM_038605189.1 → XP_038461117.1  macrophage colony-stimulating factor 1 isoform X5

    Conserved Domains (2) summary
    PHA03247
    Location:179 → 541
    PHA03247; large tegument protein UL36; Provisional
    pfam05337
    Location:25 → 164
    CSF-1; Macrophage colony stimulating factor-1 (CSF-1)

  8. XM_038605190.1 → XP_038461118.1  macrophage colony-stimulating factor 1 isoform X5

    Conserved Domains (2) summary
    PHA03247
    Location:179 → 541
    PHA03247; large tegument protein UL36; Provisional
    pfam05337
    Location:25 → 164
    CSF-1; Macrophage colony stimulating factor-1 (CSF-1)

RNA

  1. XR_005395561.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049227.1 Alternate UU_Cfam_GSD_1.0

    Range
    42485555..42505704 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038541058.1 → XP_038396986.1  macrophage colony-stimulating factor 1 isoform X3

    Conserved Domains (1) summary
    pfam05337
    Location:41 → 180
    CSF-1; Macrophage colony stimulating factor-1 (CSF-1)

  2. XM_038541053.1 → XP_038396981.1  macrophage colony-stimulating factor 1 isoform X2

    UniProtKB/TrEMBL
    A0A8I3MIU4, A0A8I3MKU0, A0A8P0SNW2
    Conserved Domains (2) summary
    PHA03307
    Location:194 → 398
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam05337
    Location:41 → 180
    CSF-1; Macrophage colony stimulating factor-1 (CSF-1)

  3. XM_038541054.1 → XP_038396982.1  macrophage colony-stimulating factor 1 isoform X2

    UniProtKB/TrEMBL
    A0A8I3MIU4, A0A8I3MKU0, A0A8P0SNW2
    Conserved Domains (2) summary
    PHA03307
    Location:194 → 398
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam05337
    Location:41 → 180
    CSF-1; Macrophage colony stimulating factor-1 (CSF-1)

  4. XM_038541052.1 → XP_038396980.1  macrophage colony-stimulating factor 1 isoform X1

    UniProtKB/TrEMBL
    A0A8I3MIU4
    Conserved Domains (2) summary
    PHA03247
    Location:195 → 557
    PHA03247; large tegument protein UL36; Provisional
    pfam05337
    Location:41 → 180
    CSF-1; Macrophage colony stimulating factor-1 (CSF-1)

  5. XM_038541055.1 → XP_038396983.1  macrophage colony-stimulating factor 1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0YYA0
    Conserved Domains (2) summary
    PHA03247
    Location:188 → 550
    PHA03247; large tegument protein UL36; Provisional
    pfam05337
    Location:34 → 173
    CSF-1; Macrophage colony stimulating factor-1 (CSF-1)

  6. XM_038541057.1 → XP_038396985.1  macrophage colony-stimulating factor 1 isoform X5

    UniProtKB/TrEMBL
    A0A8P0NM07
    Conserved Domains (2) summary
    PHA03247
    Location:179 → 541
    PHA03247; large tegument protein UL36; Provisional
    pfam05337
    Location:25 → 164
    CSF-1; Macrophage colony stimulating factor-1 (CSF-1)

  7. XM_038541056.1 → XP_038396984.1  macrophage colony-stimulating factor 1 isoform X5

    UniProtKB/TrEMBL
    A0A8P0NM07
    Conserved Domains (2) summary
    PHA03247
    Location:179 → 541
    PHA03247; large tegument protein UL36; Provisional
    pfam05337
    Location:25 → 164
    CSF-1; Macrophage colony stimulating factor-1 (CSF-1)

RNA

  1. XR_005361018.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006588.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    44804295..44823439 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038552127.1 → XP_038408055.1  macrophage colony-stimulating factor 1 isoform X3

    Conserved Domains (1) summary
    pfam05337
    Location:41 → 180
    CSF-1; Macrophage colony stimulating factor-1 (CSF-1)

  2. XM_038552097.1 → XP_038408025.1  macrophage colony-stimulating factor 1 isoform X2

    UniProtKB/TrEMBL
    A0A8I3MIU4, A0A8I3MKU0, A0A8P0SNW2
    Conserved Domains (2) summary
    PHA03307
    Location:194 → 398
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam05337
    Location:41 → 180
    CSF-1; Macrophage colony stimulating factor-1 (CSF-1)

  3. XM_038552102.1 → XP_038408030.1  macrophage colony-stimulating factor 1 isoform X2

    UniProtKB/TrEMBL
    A0A8I3MIU4, A0A8I3MKU0, A0A8P0SNW2
    Conserved Domains (2) summary
    PHA03307
    Location:194 → 398
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam05337
    Location:41 → 180
    CSF-1; Macrophage colony stimulating factor-1 (CSF-1)

  4. XM_038552087.1 → XP_038408015.1  macrophage colony-stimulating factor 1 isoform X1

    UniProtKB/TrEMBL
    A0A8I3MIU4
    Conserved Domains (2) summary
    PHA03247
    Location:195 → 557
    PHA03247; large tegument protein UL36; Provisional
    pfam05337
    Location:41 → 180
    CSF-1; Macrophage colony stimulating factor-1 (CSF-1)

  5. XM_014114755.3 → XP_013970230.1  macrophage colony-stimulating factor 1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0YYA0
    Conserved Domains (2) summary
    PHA03247
    Location:188 → 550
    PHA03247; large tegument protein UL36; Provisional
    pfam05337
    Location:34 → 173
    CSF-1; Macrophage colony stimulating factor-1 (CSF-1)

  6. XM_014114757.3 → XP_013970232.1  macrophage colony-stimulating factor 1 isoform X5

    UniProtKB/TrEMBL
    A0A8P0NM07
    Conserved Domains (2) summary
    PHA03247
    Location:179 → 541
    PHA03247; large tegument protein UL36; Provisional
    pfam05337
    Location:25 → 164
    CSF-1; Macrophage colony stimulating factor-1 (CSF-1)

RNA

  1. XR_005366662.1 RNA Sequence

Nucleotide Protein
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