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IL11 interleukin 11 [ Canis lupus familiaris (dog) ]

Gene ID: 611309, updated on 5-Mar-2024

Summary

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Official Symbol
IL11provided by VGNC
Official Full Name
interleukin 11provided by VGNC
Primary source
VGNC:VGNC:41930
See related
Ensembl:ENSCAFG00845000969
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
10
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 1 NC_051805.1 (102965197..102972306)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 1 NC_006583.4 (102368701..102375810)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 1 NC_049222.1 (103077747..103084856)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 1 NC_049261.1 (102602478..102609587)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 1 NC_049742.1 (102314584..102321607)

Chromosome 1 - NC_051805.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 238 Neighboring gene transmembrane protein 190 Neighboring gene golgi associated RAB2 interactor family member 5B Neighboring gene cytochrome c oxidase subunit 6B2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
interleukin-11

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051805.1 Reference ROS_Cfam_1.0

    Range
    102965197..102972306
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038655938.1 → XP_038511866.1  interleukin-11 isoform X1

  2. XM_038655931.1 → XP_038511859.1  interleukin-11 isoform X1

  3. XM_038655932.1 → XP_038511860.1  interleukin-11 isoform X1

  4. XM_038655936.1 → XP_038511864.1  interleukin-11 isoform X1

  5. XM_038655935.1 → XP_038511863.1  interleukin-11 isoform X1

  6. XM_038655937.1 → XP_038511865.1  interleukin-11 isoform X1

  7. XM_038655933.1 → XP_038511861.1  interleukin-11 isoform X1

  8. XM_038655934.1 → XP_038511862.1  interleukin-11 isoform X1

  9. XM_038655930.1 → XP_038511858.1  interleukin-11 isoform X1

  10. XM_038655940.1 → XP_038511868.1  interleukin-11 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QP82
    Conserved Domains (1) summary
    pfam07400
    Location:1 → 120
    IL11; Interleukin 11

  11. XM_038655939.1 → XP_038511867.1  interleukin-11 isoform X2

    UniProtKB/TrEMBL
    A0A8C0QKD2, A0A8I3MH15, A0A8I3MMT5
    Related
    ENSCAFP00845001306.1, ENSCAFT00845001654.1
    Conserved Domains (1) summary
    pfam07400
    Location:34 → 199
    IL11; Interleukin 11

  12. XM_038655941.1 → XP_038511869.1  interleukin-11 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QP82
    Conserved Domains (1) summary
    pfam07400
    Location:1 → 120
    IL11; Interleukin 11

RNA

  1. XR_005421988.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049261.1 Alternate UMICH_Zoey_3.1

    Range
    102602478..102609587
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038467131.1 → XP_038323059.1  interleukin-11 isoform X1

  2. XM_038467124.1 → XP_038323052.1  interleukin-11 isoform X1

  3. XM_038467125.1 → XP_038323053.1  interleukin-11 isoform X1

  4. XM_038467129.1 → XP_038323057.1  interleukin-11 isoform X1

  5. XM_038467128.1 → XP_038323056.1  interleukin-11 isoform X1

  6. XM_038467130.1 → XP_038323058.1  interleukin-11 isoform X1

  7. XM_038467126.1 → XP_038323054.1  interleukin-11 isoform X1

  8. XM_038467127.1 → XP_038323055.1  interleukin-11 isoform X1

  9. XM_038467123.1 → XP_038323051.1  interleukin-11 isoform X1

  10. XM_038467133.1 → XP_038323061.1  interleukin-11 isoform X3

    Conserved Domains (1) summary
    pfam07400
    Location:1 → 120
    IL11; Interleukin 11

  11. XM_038467132.1 → XP_038323060.1  interleukin-11 isoform X2

    Conserved Domains (1) summary
    pfam07400
    Location:34 → 199
    IL11; Interleukin 11

  12. XM_038467134.1 → XP_038323062.1  interleukin-11 isoform X3

    Conserved Domains (1) summary
    pfam07400
    Location:1 → 120
    IL11; Interleukin 11

RNA

  1. XR_005320803.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049742.1 Alternate UNSW_CanFamBas_1.0

    Range
    102314584..102321607
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038592176.1 → XP_038448104.1  interleukin-11 isoform X3

    Conserved Domains (1) summary
    pfam07400
    Location:1 → 120
    IL11; Interleukin 11

  2. XM_038592175.1 → XP_038448103.1  interleukin-11 isoform X2

    Conserved Domains (1) summary
    pfam07400
    Location:34 → 199
    IL11; Interleukin 11

  3. XM_038592177.1 → XP_038448105.1  interleukin-11 isoform X3

    Conserved Domains (1) summary
    pfam07400
    Location:1 → 120
    IL11; Interleukin 11

RNA

  1. XR_005389019.1 RNA Sequence

  2. XR_005389020.1 RNA Sequence

  3. XR_005389024.1 RNA Sequence

  4. XR_005389022.1 RNA Sequence

  5. XR_005389023.1 RNA Sequence

  6. XR_005389021.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049222.1 Alternate UU_Cfam_GSD_1.0

    Range
    103077747..103084856
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038527858.1 → XP_038383786.1  interleukin-11 isoform X1

  2. XM_038527851.1 → XP_038383779.1  interleukin-11 isoform X1

  3. XM_038527852.1 → XP_038383780.1  interleukin-11 isoform X1

  4. XM_038527856.1 → XP_038383784.1  interleukin-11 isoform X1

  5. XM_038527855.1 → XP_038383783.1  interleukin-11 isoform X1

  6. XM_038527857.1 → XP_038383785.1  interleukin-11 isoform X1

  7. XM_038527853.1 → XP_038383781.1  interleukin-11 isoform X1

  8. XM_038527854.1 → XP_038383782.1  interleukin-11 isoform X1

  9. XM_038527850.1 → XP_038383778.1  interleukin-11 isoform X1

  10. XM_038527860.1 → XP_038383788.1  interleukin-11 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QP82
    Conserved Domains (1) summary
    pfam07400
    Location:1 → 120
    IL11; Interleukin 11

  11. XM_038527859.1 → XP_038383787.1  interleukin-11 isoform X2

    UniProtKB/TrEMBL
    A0A8C0QKD2, A0A8I3MH15, A0A8I3MMT5
    Conserved Domains (1) summary
    pfam07400
    Location:34 → 199
    IL11; Interleukin 11

  12. XM_038527861.1 → XP_038383789.1  interleukin-11 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QP82
    Conserved Domains (1) summary
    pfam07400
    Location:1 → 120
    IL11; Interleukin 11

RNA

  1. XR_005354448.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    102368701..102375810
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038645104.1 → XP_038501032.1  interleukin-11 isoform X1

  2. XM_022427533.2 → XP_022283241.1  interleukin-11 isoform X1

  3. XM_022427535.2 → XP_022283243.1  interleukin-11 isoform X1

  4. XM_022427538.2 → XP_022283246.1  interleukin-11 isoform X1

  5. XM_022427542.2 → XP_022283250.1  interleukin-11 isoform X1

  6. XM_022427544.2 → XP_022283252.1  interleukin-11 isoform X1

  7. XM_022427536.2 → XP_022283244.1  interleukin-11 isoform X1

  8. XM_022427537.2 → XP_022283245.1  interleukin-11 isoform X1

  9. XM_022427532.2 → XP_022283240.1  interleukin-11 isoform X1

  10. XM_022427551.2 → XP_022283259.1  interleukin-11 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QP82
    Conserved Domains (1) summary
    pfam07400
    Location:1 → 120
    IL11; Interleukin 11

  11. XM_022427547.2 → XP_022283255.1  interleukin-11 isoform X2

    UniProtKB/TrEMBL
    A0A8C0QKD2, A0A8I3MH15, A0A8I3MMT5
    Conserved Domains (1) summary
    pfam07400
    Location:34 → 199
    IL11; Interleukin 11

  12. XM_038645328.1 → XP_038501256.1  interleukin-11 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QP82
    Conserved Domains (1) summary
    pfam07400
    Location:1 → 120
    IL11; Interleukin 11

RNA

  1. XR_002633083.2 RNA Sequence

Nucleotide Protein
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