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GDF10 growth differentiation factor 10 [ Canis lupus familiaris (dog) ]

Gene ID: 611168, updated on 5-Mar-2024

Summary

Official Symbol
GDF10provided by VGNC
Official Full Name
growth differentiation factor 10provided by VGNC
Primary source
VGNC:VGNC:41158
See related
Ensembl:ENSCAFG00845008410
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

See GDF10 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
3
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 4 NC_051808.1 (35368659..35377901, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 4 NC_006586.4 (34972559..34981749, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 4 NC_049225.1 (35889219..35898460, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 4 NC_049264.1 (35200361..35209442, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 4 NC_049745.1 (35381596..35390831, complement)

Chromosome 4 - NC_051808.1Genomic Context describing neighboring genes Neighboring gene retinol binding protein 3 Neighboring gene growth differentiation factor 2 Neighboring gene uncharacterized LOC111095521 Neighboring gene uncharacterized LOC111095522

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in BMP signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in SMAD protein signal transduction IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in osteoblast differentiation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
bone morphogenetic protein 3B; LOW QUALITY PROTEIN: growth/differentiation factor 10; growth/differentiation factor 10

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051808.1 Reference ROS_Cfam_1.0

    Range
    35368659..35377901 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038662370.1XP_038518298.1  growth/differentiation factor 10

    UniProtKB/TrEMBL
    A0A8C0SEX6, A0A8I3N6I7, A0A8P0NHU7
    Related
    ENSCAFP00845011457.1, ENSCAFT00845014787.1
    Conserved Domains (1) summary
    cd19394
    Location:372483
    TGF_beta_GDF10; transforming growth factor beta (TGF-beta) like domain found in growth/differentiation factor 10 (GDF10) and similar proteins

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049264.1 Alternate UMICH_Zoey_3.1

    Range
    35200361..35209442 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038474323.1XP_038330251.1  LOW QUALITY PROTEIN: growth/differentiation factor 10

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049745.1 Alternate UNSW_CanFamBas_1.0

    Range
    35381596..35390831 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038598062.1XP_038453990.1  LOW QUALITY PROTEIN: growth/differentiation factor 10

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049225.1 Alternate UU_Cfam_GSD_1.0

    Range
    35889219..35898460 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038535449.1XP_038391377.1  growth/differentiation factor 10

    UniProtKB/TrEMBL
    A0A8C0LVN3, A0A8C0SEX6

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006586.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    34972559..34981749 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_848811.6XP_853904.2  growth/differentiation factor 10

    UniProtKB/TrEMBL
    A0A8C0SEX6, A0A8I3N6I7, A0A8P0NHU7
    Conserved Domains (1) summary
    cd19394
    Location:372483
    TGF_beta_GDF10; transforming growth factor beta (TGF-beta) like domain found in growth/differentiation factor 10 (GDF10) and similar proteins