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NR1H2 nuclear receptor subfamily 1 group H member 2 [ Canis lupus familiaris (dog) ]

Gene ID: 610057, updated on 5-Mar-2024

Summary

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Official Symbol
NR1H2provided by VGNC
Official Full Name
nuclear receptor subfamily 1 group H member 2provided by VGNC
Primary source
VGNC:VGNC:43942
See related
Ensembl:ENSCAFG00845018363
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
10
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 1 NC_051805.1 (106843783..106850258, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 1 NC_006583.4 (105905786..105912261, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 1 NC_049222.1 (106998070..107004546, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 1 NC_049261.1 (106515887..106522355, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 1 NC_049742.1 (106157420..106163895, complement)

Chromosome 1 - NC_051805.1Genomic Context describing neighboring genes Neighboring gene Spi-B transcription factor Neighboring gene DNA polymerase delta 1, catalytic subunit Neighboring gene napsin A aspartic peptidase Neighboring gene uncharacterized LOC119870938 Neighboring gene potassium voltage-gated channel subfamily C member 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
oxysterols receptor LXR-beta

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051805.1 Reference ROS_Cfam_1.0

    Range
    106843783..106850258 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038656192.1 → XP_038512120.1  oxysterols receptor LXR-beta

    UniProtKB/TrEMBL
    A0A8C0L554, A0A8C0SEE4, A0A8I3NW80
    Conserved Domains (2) summary
    cd06954
    Location:218 → 453
    NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
    cl02596
    Location:65 → 161
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

  2. XM_038656190.1 → XP_038512118.1  oxysterols receptor LXR-beta

    UniProtKB/TrEMBL
    A0A8C0L554, A0A8C0SEE4, A0A8I3NW80
    Conserved Domains (2) summary
    cd06954
    Location:218 → 453
    NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
    cl02596
    Location:65 → 161
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

  3. XM_038656191.1 → XP_038512119.1  oxysterols receptor LXR-beta

    UniProtKB/TrEMBL
    A0A8C0L554, A0A8C0SEE4, A0A8I3NW80
    Related
    ENSCAFP00845025424.1, ENSCAFT00845032512.1
    Conserved Domains (2) summary
    cd06954
    Location:218 → 453
    NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
    cl02596
    Location:65 → 161
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049261.1 Alternate UMICH_Zoey_3.1

    Range
    106515887..106522355 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038467405.1 → XP_038323333.1  oxysterols receptor LXR-beta

    Conserved Domains (2) summary
    cd06954
    Location:218 → 453
    NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
    cl02596
    Location:65 → 161
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

  2. XM_038467403.1 → XP_038323331.1  oxysterols receptor LXR-beta

    Conserved Domains (2) summary
    cd06954
    Location:218 → 453
    NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
    cl02596
    Location:65 → 161
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

  3. XM_038467404.1 → XP_038323332.1  oxysterols receptor LXR-beta

    Conserved Domains (2) summary
    cd06954
    Location:218 → 453
    NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
    cl02596
    Location:65 → 161
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049742.1 Alternate UNSW_CanFamBas_1.0

    Range
    106157420..106163895 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038592400.1 → XP_038448328.1  oxysterols receptor LXR-beta

    Conserved Domains (2) summary
    cd06954
    Location:218 → 453
    NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
    cl02596
    Location:65 → 161
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

  2. XM_038592398.1 → XP_038448326.1  oxysterols receptor LXR-beta

    Conserved Domains (2) summary
    cd06954
    Location:218 → 453
    NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
    cl02596
    Location:65 → 161
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

  3. XM_038592399.1 → XP_038448327.1  oxysterols receptor LXR-beta

    Conserved Domains (2) summary
    cd06954
    Location:218 → 453
    NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
    cl02596
    Location:65 → 161
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049222.1 Alternate UU_Cfam_GSD_1.0

    Range
    106998070..107004546 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038528103.1 → XP_038384031.1  oxysterols receptor LXR-beta

    UniProtKB/TrEMBL
    A0A8C0L554, A0A8C0SEE4, A0A8I3NW80
    Conserved Domains (2) summary
    cd06954
    Location:218 → 453
    NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
    cl02596
    Location:65 → 161
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

  2. XM_038528101.1 → XP_038384029.1  oxysterols receptor LXR-beta

    UniProtKB/TrEMBL
    A0A8C0L554, A0A8C0SEE4, A0A8I3NW80
    Conserved Domains (2) summary
    cd06954
    Location:218 → 453
    NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
    cl02596
    Location:65 → 161
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

  3. XM_038528102.1 → XP_038384030.1  oxysterols receptor LXR-beta

    UniProtKB/TrEMBL
    A0A8C0L554, A0A8C0SEE4, A0A8I3NW80
    Conserved Domains (2) summary
    cd06954
    Location:218 → 453
    NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
    cl02596
    Location:65 → 161
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    105905786..105912261 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022423354.2 → XP_022279062.1  oxysterols receptor LXR-beta

    UniProtKB/TrEMBL
    A0A8C0L554, A0A8C0SEE4, A0A8I3NW80
    Conserved Domains (2) summary
    cd06954
    Location:218 → 453
    NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
    cl02596
    Location:65 → 161
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

  2. XM_005616270.4 → XP_005616327.1  oxysterols receptor LXR-beta

    See identical proteins and their annotated locations for XP_005616327.1

    UniProtKB/TrEMBL
    A0A8C0L554, A0A8C0SEE4, A0A8I3NW80
    Conserved Domains (2) summary
    cd06954
    Location:218 → 453
    NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
    cl02596
    Location:65 → 161
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

  3. XM_846223.6 → XP_851316.1  oxysterols receptor LXR-beta

    See identical proteins and their annotated locations for XP_851316.1

    UniProtKB/TrEMBL
    A0A8C0L554, A0A8C0SEE4, A0A8I3NW80
    Conserved Domains (2) summary
    cd06954
    Location:218 → 453
    NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
    cl02596
    Location:65 → 161
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers
Nucleotide Protein
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