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E2F6 E2F transcription factor 6 [ Canis lupus familiaris (dog) ]

Gene ID: 609996, updated on 5-Mar-2024

Summary

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Official Symbol
E2F6provided by VGNC
Official Full Name
E2F transcription factor 6provided by VGNC
Primary source
VGNC:VGNC:40168
See related
Ensembl:ENSCAFG00845028092
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 17
Exon count:
10
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 17 NC_051821.1 (8259457..8281868, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 17 NC_006599.4 (8087626..8109839, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 17 NC_049238.1 (8167391..8189717, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 17 NC_049277.1 (8144343..8166581, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 17 NC_049758.1 (8148116..8170364, complement)

Chromosome 17 - NC_051821.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111090494 Neighboring gene uncharacterized LOC119869774 Neighboring gene uncharacterized LOC111090495 Neighboring gene uncharacterized LOC119869769 Neighboring gene growth regulating estrogen receptor binding 1 Neighboring gene neurotensin receptor 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of RNA polymerase II transcription regulator complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transcription factor E2F6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051821.1 Reference ROS_Cfam_1.0

    Range
    8259457..8281868 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038690724.1 → XP_038546652.1  transcription factor E2F6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LS27, A0A8C0QL87, A0A8I3QHA1
    Related
    ENSCAFP00845038931.1, ENSCAFT00845049633.1
    Conserved Domains (2) summary
    cd14660
    Location:139 → 239
    E2F_DD; Dimerization domain of E2F transcription factors
    pfam02319
    Location:65 → 128
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain

  2. XM_038690725.1 → XP_038546653.1  transcription factor E2F6 isoform X2

    UniProtKB/TrEMBL
    A0A8C0QNP5, A0A8I3PVQ9
    Related
    ENSCAFP00845038970.1, ENSCAFT00845049691.1
    Conserved Domains (2) summary
    cd14660
    Location:87 → 187
    E2F_DD; Dimerization domain of E2F transcription factors
    pfam02319
    Location:13 → 76
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain

  3. XM_038690726.1 → XP_038546654.1  transcription factor E2F6 isoform X2

    UniProtKB/TrEMBL
    A0A8C0QNP5, A0A8I3PVQ9
    Related
    ENSCAFP00845038985.1, ENSCAFT00845049711.1
    Conserved Domains (2) summary
    cd14660
    Location:87 → 187
    E2F_DD; Dimerization domain of E2F transcription factors
    pfam02319
    Location:13 → 76
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain

  4. XM_038690727.1 → XP_038546655.1  transcription factor E2F6 isoform X3

    Conserved Domains (1) summary
    cd14660
    Location:1 → 87
    E2F_DD; Dimerization domain of E2F transcription factors

RNA

  1. XR_005439855.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049277.1 Alternate UMICH_Zoey_3.1

    Range
    8144343..8166581 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038498250.1 → XP_038354178.1  transcription factor E2F6 isoform X1

    Conserved Domains (2) summary
    cd14660
    Location:139 → 239
    E2F_DD; Dimerization domain of E2F transcription factors
    pfam02319
    Location:65 → 128
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain

  2. XM_038498251.1 → XP_038354179.1  transcription factor E2F6 isoform X2

    Conserved Domains (2) summary
    cd14660
    Location:87 → 187
    E2F_DD; Dimerization domain of E2F transcription factors
    pfam02319
    Location:13 → 76
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain

  3. XM_038498252.1 → XP_038354180.1  transcription factor E2F6 isoform X2

    Conserved Domains (2) summary
    cd14660
    Location:87 → 187
    E2F_DD; Dimerization domain of E2F transcription factors
    pfam02319
    Location:13 → 76
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain

  4. XM_038498253.1 → XP_038354181.1  transcription factor E2F6 isoform X3

    Conserved Domains (1) summary
    cd14660
    Location:1 → 87
    E2F_DD; Dimerization domain of E2F transcription factors

RNA

  1. XR_005338309.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049758.1 Alternate UNSW_CanFamBas_1.0

    Range
    8148116..8170364 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038624814.1 → XP_038480742.1  transcription factor E2F6 isoform X1

    Conserved Domains (2) summary
    cd14660
    Location:139 → 239
    E2F_DD; Dimerization domain of E2F transcription factors
    pfam02319
    Location:65 → 128
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain

  2. XM_038624815.1 → XP_038480743.1  transcription factor E2F6 isoform X2

    Conserved Domains (2) summary
    cd14660
    Location:87 → 187
    E2F_DD; Dimerization domain of E2F transcription factors
    pfam02319
    Location:13 → 76
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain

  3. XM_038624816.1 → XP_038480744.1  transcription factor E2F6 isoform X2

    Conserved Domains (2) summary
    cd14660
    Location:87 → 187
    E2F_DD; Dimerization domain of E2F transcription factors
    pfam02319
    Location:13 → 76
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain

  4. XM_038624817.1 → XP_038480745.1  transcription factor E2F6 isoform X3

    Conserved Domains (1) summary
    cd14660
    Location:1 → 87
    E2F_DD; Dimerization domain of E2F transcription factors

RNA

  1. XR_005406203.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049238.1 Alternate UU_Cfam_GSD_1.0

    Range
    8167391..8189717 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038560787.1 → XP_038416715.1  transcription factor E2F6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LS27, A0A8C0QL87, A0A8I3QHA1
    Conserved Domains (2) summary
    cd14660
    Location:139 → 239
    E2F_DD; Dimerization domain of E2F transcription factors
    pfam02319
    Location:65 → 128
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain

  2. XM_038560788.1 → XP_038416716.1  transcription factor E2F6 isoform X2

    UniProtKB/TrEMBL
    A0A8C0QNP5, A0A8I3PVQ9
    Conserved Domains (2) summary
    cd14660
    Location:87 → 187
    E2F_DD; Dimerization domain of E2F transcription factors
    pfam02319
    Location:13 → 76
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain

  3. XM_038560789.1 → XP_038416717.1  transcription factor E2F6 isoform X2

    UniProtKB/TrEMBL
    A0A8C0QNP5, A0A8I3PVQ9
    Conserved Domains (2) summary
    cd14660
    Location:87 → 187
    E2F_DD; Dimerization domain of E2F transcription factors
    pfam02319
    Location:13 → 76
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain

  4. XM_038560790.1 → XP_038416718.1  transcription factor E2F6 isoform X3

    Conserved Domains (1) summary
    cd14660
    Location:1 → 87
    E2F_DD; Dimerization domain of E2F transcription factors

RNA

  1. XR_005372102.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006599.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    8087626..8109839 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_847370.5 → XP_852463.1  transcription factor E2F6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LS27, A0A8C0QL87, A0A8I3QHA1
    Conserved Domains (2) summary
    cd14660
    Location:139 → 239
    E2F_DD; Dimerization domain of E2F transcription factors
    pfam02319
    Location:65 → 128
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain

  2. XM_005630127.3 → XP_005630184.1  transcription factor E2F6 isoform X2

    See identical proteins and their annotated locations for XP_005630184.1

    UniProtKB/TrEMBL
    A0A8C0QNP5, A0A8I3PVQ9
    Conserved Domains (2) summary
    cd14660
    Location:87 → 187
    E2F_DD; Dimerization domain of E2F transcription factors
    pfam02319
    Location:13 → 76
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain

  3. XM_022404453.2 → XP_022260161.1  transcription factor E2F6 isoform X2

    UniProtKB/TrEMBL
    A0A8C0QNP5, A0A8I3PVQ9
    Conserved Domains (2) summary
    cd14660
    Location:87 → 187
    E2F_DD; Dimerization domain of E2F transcription factors
    pfam02319
    Location:13 → 76
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain

  4. XM_022404454.2 → XP_022260162.1  transcription factor E2F6 isoform X3

    Conserved Domains (1) summary
    cd14660
    Location:1 → 87
    E2F_DD; Dimerization domain of E2F transcription factors

RNA

  1. XR_294473.4 RNA Sequence

Nucleotide Protein
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