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PDE4C phosphodiesterase 4C [ Canis lupus familiaris (dog) ]

Gene ID: 609938, updated on 5-Mar-2024

Summary

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Official Symbol
PDE4Cprovided by VGNC
Official Full Name
phosphodiesterase 4Cprovided by VGNC
Primary source
VGNC:VGNC:49938
See related
Ensembl:ENSCAFG00845022978
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 20
Exon count:
16
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (45261030..45278277)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (44689267..44706455)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (45184206..45201379)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (44498073..44515446)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (44908785..44925897)

Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene IQ motif containing N Neighboring gene uncharacterized LOC111091450 Neighboring gene RAB3A, member RAS oncogene family Neighboring gene MPV17 mitochondrial inner membrane protein like 2 Neighboring gene IFI30 lysosomal thiol reductase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3',5'-cyclic-AMP phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cAMP-specific 3',5'-cyclic phosphodiesterase 4C
Names
phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila)
XP_013977824.1
XP_038284093.1
XP_038284094.1
XP_038311674.1
XP_038359752.1
XP_038359753.1
XP_038422763.1
XP_038422764.1
XP_038486917.1
XP_038486918.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051824.1 Reference ROS_Cfam_1.0

    Range
    45261030..45278277
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038428165.1 → XP_038284093.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X1

    UniProtKB/TrEMBL
    A0A8I3PIA4, A0A8I3S3F5
    Related
    ENSCAFP00845031903.1, ENSCAFT00845040752.1
    Conserved Domains (2) summary
    pfam00233
    Location:387 → 628
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam18100
    Location:151 → 268
    PDE4_UCR; Phosphodiesterase 4 upstream conserved regions (UCR)

  2. XM_038428166.1 → XP_038284094.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X2

    UniProtKB/TrEMBL
    A0A8I3PIA4
    Related
    ENSCAFP00845031974.1, ENSCAFT00845040833.1
    Conserved Domains (2) summary
    pfam00233
    Location:368 → 609
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam18100
    Location:120 → 237
    PDE4_UCR; Phosphodiesterase 4 upstream conserved regions (UCR)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049280.1 Alternate UMICH_Zoey_3.1

    Range
    44498073..44515446
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038503824.1 → XP_038359752.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X1

    Conserved Domains (2) summary
    pfam00233
    Location:387 → 628
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam18100
    Location:151 → 268
    PDE4_UCR; Phosphodiesterase 4 upstream conserved regions (UCR)

  2. XM_038503825.1 → XP_038359753.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X2

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

    Range
    44908785..44925897
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038630989.1 → XP_038486917.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X1

  2. XM_038630990.1 → XP_038486918.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X2

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

    Range
    45184206..45201379
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038566835.1 → XP_038422763.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X1

    UniProtKB/TrEMBL
    A0A8I3PIA4, A0A8P0SUB5

  2. XM_038566836.1 → XP_038422764.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X2

    UniProtKB/TrEMBL
    A0A8I3PIA4, A0A8P0SUB5

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    44689267..44706455
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038455746.1 → XP_038311674.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X1

    UniProtKB/TrEMBL
    A0A8C0NH75, A0A8P0NGK5, A0A8P0SUB5
    Conserved Domains (2) summary
    pfam00233
    Location:387 → 628
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam18100
    Location:151 → 268
    PDE4_UCR; Phosphodiesterase 4 upstream conserved regions (UCR)

  2. XM_014122349.3 → XP_013977824.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X2

    UniProtKB/TrEMBL
    A0A8P0SUB5
    Conserved Domains (1) summary
    pfam00233
    Location:368 → 609
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
Nucleotide Protein
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