U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CDK6 cyclin dependent kinase 6 [ Canis lupus familiaris (dog) ]

Gene ID: 609920, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
CDK6provided by VGNC
Official Full Name
cyclin dependent kinase 6provided by VGNC
Primary source
VGNC:VGNC:54756
See related
Ensembl:ENSCAFG00845013226
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 14
Exon count:
10
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 14 NC_051818.1 (17990661..18231585, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 14 NC_006596.4 (17739051..17984302, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 14 NC_049235.1 (18137407..18377659, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 14 NC_049274.1 (18145467..18391128, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 14 NC_049755.1 (17862908..18101297, complement)

Chromosome 14 - NC_051818.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L21-like Neighboring gene family with sequence similarity 133 member B Neighboring gene ubiquitin-like modifier-activating enzyme 5 Neighboring gene uncharacterized LOC102152579 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC119880330 Neighboring gene uncharacterized LOC111098751

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cyclin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cyclin-dependent protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G1/S transition of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell dedifferentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of G2/M transition of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of cyclin-dependent protein kinase holoenzyme complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
cyclin-dependent kinase 6
XP_038292079.1
XP_038292081.1
XP_038292083.1
XP_038292086.1
XP_038292088.1
XP_038350458.1
XP_038350459.1
XP_038350460.1
XP_038350461.1
XP_038350462.1
XP_038412750.1
XP_038412751.1
XP_038412752.1
XP_038412753.1
XP_038412754.1
XP_038476684.1
XP_038476685.1
XP_038476686.1
XP_038476688.1
XP_038476689.1
XP_038542371.1
XP_038542372.1
XP_038542373.1
XP_038542374.1
XP_038542375.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051818.1 Reference ROS_Cfam_1.0

    Range
    17990661..18231585 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038686444.1 → XP_038542372.1  cyclin-dependent kinase 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0TA97, A0A8I3RZY6
    Related
    ENSCAFP00845018501.1, ENSCAFT00845023565.1
    Conserved Domains (1) summary
    cd07862
    Location:11 → 300
    STKc_CDK6; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 6

  2. XM_038686445.1 → XP_038542373.1  cyclin-dependent kinase 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0TA97, A0A8I3RZY6
    Conserved Domains (1) summary
    cd07862
    Location:11 → 300
    STKc_CDK6; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 6

  3. XM_038686447.1 → XP_038542375.1  cyclin-dependent kinase 6 isoform X2

    Conserved Domains (1) summary
    cl21453
    Location:11 → 283
    PKc_like; Protein Kinases, catalytic domain

  4. XM_038686446.1 → XP_038542374.1  cyclin-dependent kinase 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0TA97, A0A8I3RZY6
    Conserved Domains (1) summary
    cd07862
    Location:11 → 300
    STKc_CDK6; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 6

  5. XM_038686443.1 → XP_038542371.1  cyclin-dependent kinase 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0TA97, A0A8I3RZY6
    Conserved Domains (1) summary
    cd07862
    Location:11 → 300
    STKc_CDK6; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 6

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049274.1 Alternate UMICH_Zoey_3.1

    Range
    18145467..18391128 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038494531.1 → XP_038350459.1  cyclin-dependent kinase 6 isoform X1

    Conserved Domains (1) summary
    cd07862
    Location:11 → 300
    STKc_CDK6; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 6

  2. XM_038494532.1 → XP_038350460.1  cyclin-dependent kinase 6 isoform X1

    Conserved Domains (1) summary
    cd07862
    Location:11 → 300
    STKc_CDK6; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 6

  3. XM_038494534.1 → XP_038350462.1  cyclin-dependent kinase 6 isoform X2

    Conserved Domains (1) summary
    cl21453
    Location:11 → 283
    PKc_like; Protein Kinases, catalytic domain

  4. XM_038494533.1 → XP_038350461.1  cyclin-dependent kinase 6 isoform X1

    Conserved Domains (1) summary
    cd07862
    Location:11 → 300
    STKc_CDK6; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 6

  5. XM_038494530.1 → XP_038350458.1  cyclin-dependent kinase 6 isoform X1

    Conserved Domains (1) summary
    cd07862
    Location:11 → 300
    STKc_CDK6; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 6

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049755.1 Alternate UNSW_CanFamBas_1.0

    Range
    17862908..18101297 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038620757.1 → XP_038476685.1  cyclin-dependent kinase 6 isoform X1

    Conserved Domains (1) summary
    cd07862
    Location:11 → 300
    STKc_CDK6; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 6

  2. XM_038620758.1 → XP_038476686.1  cyclin-dependent kinase 6 isoform X1

    Conserved Domains (1) summary
    cd07862
    Location:11 → 300
    STKc_CDK6; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 6

  3. XM_038620761.1 → XP_038476689.1  cyclin-dependent kinase 6 isoform X2

    Conserved Domains (1) summary
    cl21453
    Location:11 → 283
    PKc_like; Protein Kinases, catalytic domain

  4. XM_038620760.1 → XP_038476688.1  cyclin-dependent kinase 6 isoform X1

    Conserved Domains (1) summary
    cd07862
    Location:11 → 300
    STKc_CDK6; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 6

  5. XM_038620756.1 → XP_038476684.1  cyclin-dependent kinase 6 isoform X1

    Conserved Domains (1) summary
    cd07862
    Location:11 → 300
    STKc_CDK6; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 6

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049235.1 Alternate UU_Cfam_GSD_1.0

    Range
    18137407..18377659 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038556823.1 → XP_038412751.1  cyclin-dependent kinase 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0TA97, A0A8I3RZY6
    Conserved Domains (1) summary
    cd07862
    Location:11 → 300
    STKc_CDK6; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 6

  2. XM_038556824.1 → XP_038412752.1  cyclin-dependent kinase 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0TA97, A0A8I3RZY6
    Conserved Domains (1) summary
    cd07862
    Location:11 → 300
    STKc_CDK6; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 6

  3. XM_038556826.1 → XP_038412754.1  cyclin-dependent kinase 6 isoform X2

    Conserved Domains (1) summary
    cl21453
    Location:11 → 283
    PKc_like; Protein Kinases, catalytic domain

  4. XM_038556825.1 → XP_038412753.1  cyclin-dependent kinase 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0TA97, A0A8I3RZY6
    Conserved Domains (1) summary
    cd07862
    Location:11 → 300
    STKc_CDK6; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 6

  5. XM_038556822.1 → XP_038412750.1  cyclin-dependent kinase 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0TA97, A0A8I3RZY6
    Conserved Domains (1) summary
    cd07862
    Location:11 → 300
    STKc_CDK6; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 6

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006596.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    17739051..17984302 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038436153.1 → XP_038292081.1  cyclin-dependent kinase 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0TA97, A0A8I3RZY6
    Conserved Domains (1) summary
    cd07862
    Location:11 → 300
    STKc_CDK6; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 6

  2. XM_038436155.1 → XP_038292083.1  cyclin-dependent kinase 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0TA97, A0A8I3RZY6
    Conserved Domains (1) summary
    cd07862
    Location:11 → 300
    STKc_CDK6; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 6

  3. XM_038436160.1 → XP_038292088.1  cyclin-dependent kinase 6 isoform X2

    Conserved Domains (1) summary
    cl21453
    Location:11 → 283
    PKc_like; Protein Kinases, catalytic domain

  4. XM_038436158.1 → XP_038292086.1  cyclin-dependent kinase 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0TA97, A0A8I3RZY6
    Conserved Domains (1) summary
    cd07862
    Location:11 → 300
    STKc_CDK6; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 6

  5. XM_038436151.1 → XP_038292079.1  cyclin-dependent kinase 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0TA97, A0A8I3RZY6
    Conserved Domains (1) summary
    cd07862
    Location:11 → 300
    STKc_CDK6; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 6
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Miscellaneous