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POFUT1 protein O-fucosyltransferase 1 [ Canis lupus familiaris (dog) ]

Gene ID: 609881, updated on 5-Mar-2024

Summary

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Official Symbol
POFUT1provided by VGNC
Official Full Name
protein O-fucosyltransferase 1provided by VGNC
Primary source
VGNC:VGNC:44767
See related
Ensembl:ENSCAFG00845020869
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 24
Exon count:
8
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 24 NC_051828.1 (22295373..22325022)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 24 NC_006606.4 (21255008..21280646)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 24 NC_049245.1 (22110055..22136141)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 24 NC_049284.1 (21573904..21599988)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 24 NC_049765.1 (21679257..21705352)

Chromosome 24 - NC_051828.1Genomic Context describing neighboring genes Neighboring gene transmembrane 9 superfamily member 4 Neighboring gene uncharacterized LOC111092032 Neighboring gene PLAG1 like zinc finger 2 Neighboring gene uncharacterized LOC111092036 Neighboring gene kinesin family member 3B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular evolution of protein O-fucosyltransferase genes and splice variants. Loriol C, et al. Glycobiology, 2006 Aug. PMID 16679357

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables peptide-O-fucosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein O-linked fucosylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
GDP-fucose protein O-fucosyltransferase 1
NP_001070825.1
XP_038288768.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001077357.1 → NP_001070825.1  GDP-fucose protein O-fucosyltransferase 1 precursor

    See identical proteins and their annotated locations for NP_001070825.1

    Status: PROVISIONAL

    Source sequence(s)
    DQ139940
    UniProtKB/TrEMBL
    A0A8P0SCM8, Q00P48
    Related
    ENSCAFP00845028826.1, ENSCAFT00845036817.1
    Conserved Domains (2) summary
    cd11302
    Location:33 → 382
    O-FucT-1; GDP-fucose protein O-fucosyltransferase 1
    pfam10250
    Location:43 → 374
    O-FucT; GDP-fucose protein O-fucosyltransferase

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051828.1 Reference ROS_Cfam_1.0

    Range
    22295373..22325022
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038432840.1 → XP_038288768.1  GDP-fucose protein O-fucosyltransferase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8P0SCM8
    Conserved Domains (1) summary
    cd11302
    Location:15 → 356
    O-FucT-1; GDP-fucose protein O-fucosyltransferase 1

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049284.1 Alternate UMICH_Zoey_3.1

    Range
    21573904..21599988
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049765.1 Alternate UNSW_CanFamBas_1.0

    Range
    21679257..21705352
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049245.1 Alternate UU_Cfam_GSD_1.0

    Range
    22110055..22136141
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006606.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    21255008..21280646
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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