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CHEK1 checkpoint kinase 1 [ Canis lupus familiaris (dog) ]

Gene ID: 609767, updated on 5-Mar-2024

Summary

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Official Symbol
CHEK1provided by VGNC
Official Full Name
checkpoint kinase 1provided by VGNC
Primary source
VGNC:VGNC:53319
See related
Ensembl:ENSCAFG00845010598
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
15
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 5 NC_051809.1 (8821650..8853260, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 5 NC_006587.4 (8923479..8955720, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 5 NC_049226.1 (8897288..8929731, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 5 NC_049265.1 (8890756..8922634, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 5 NC_049746.1 (8860679..8892710, complement)

Chromosome 5 - NC_051809.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119871787 Neighboring gene uncharacterized LOC119871788 Neighboring gene uncharacterized LOC119876288 Neighboring gene acrosomal vesicle protein 1 Neighboring gene STT3 oligosaccharyltransferase complex catalytic subunit A Neighboring gene EI24 autophagy associated transmembrane protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitotic G2 DNA damage checkpoint signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in site of double-strand break IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase Chk1
Names
CHK1 checkpoint homolog
XP_038333526.1
XP_038333527.1
XP_038359774.1
XP_038359782.1
XP_038391416.1
XP_038391417.1
XP_038455638.1
XP_038455639.1
XP_038520162.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051809.1 Reference ROS_Cfam_1.0

    Range
    8821650..8853260 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038664234.1 → XP_038520162.1  serine/threonine-protein kinase Chk1 isoform X1

    UniProtKB/TrEMBL
    A0A8I3NB92
    Related
    ENSCAFP00845014658.1, ENSCAFT00845018774.1
    Conserved Domains (1) summary
    cd14069
    Location:7 → 265
    STKc_Chk1; Catalytic domain of the Serine/Threonine kinase, Checkpoint kinase 1

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049265.1 Alternate UMICH_Zoey_3.1

    Range
    8890756..8922634 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038477599.1 → XP_038333527.1  serine/threonine-protein kinase Chk1 isoform X3

    Conserved Domains (1) summary
    cd14069
    Location:1 → 224
    STKc_Chk1; Catalytic domain of the Serine/Threonine kinase, Checkpoint kinase 1

  2. XM_038477598.1 → XP_038333526.1  serine/threonine-protein kinase Chk1 isoform X2

    Conserved Domains (1) summary
    cd14069
    Location:7 → 265
    STKc_Chk1; Catalytic domain of the Serine/Threonine kinase, Checkpoint kinase 1

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049746.1 Alternate UNSW_CanFamBas_1.0

    Range
    8860679..8892710 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038599711.1 → XP_038455639.1  serine/threonine-protein kinase Chk1 isoform X5

    Conserved Domains (1) summary
    cd14069
    Location:1 → 224
    STKc_Chk1; Catalytic domain of the Serine/Threonine kinase, Checkpoint kinase 1

  2. XM_038599710.1 → XP_038455638.1  serine/threonine-protein kinase Chk1 isoform X4

    Conserved Domains (1) summary
    cd14069
    Location:7 → 265
    STKc_Chk1; Catalytic domain of the Serine/Threonine kinase, Checkpoint kinase 1

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049226.1 Alternate UU_Cfam_GSD_1.0

    Range
    8897288..8929731 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038535489.1 → XP_038391417.1  serine/threonine-protein kinase Chk1 isoform X7

    UniProtKB/TrEMBL
    A0A8I3NB92
    Conserved Domains (1) summary
    cd14069
    Location:1 → 224
    STKc_Chk1; Catalytic domain of the Serine/Threonine kinase, Checkpoint kinase 1

  2. XM_038535488.1 → XP_038391416.1  serine/threonine-protein kinase Chk1 isoform X6

    UniProtKB/TrEMBL
    A0A8C0QZ09, A0A8C0Z0K6, A0A8I3NB92, A0A8P0SFN3
    Conserved Domains (1) summary
    cd14069
    Location:7 → 265
    STKc_Chk1; Catalytic domain of the Serine/Threonine kinase, Checkpoint kinase 1

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006587.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    8923479..8955720 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038503854.1 → XP_038359782.1  serine/threonine-protein kinase Chk1 isoform X9

    UniProtKB/TrEMBL
    A0A8I3NB92
    Conserved Domains (1) summary
    cd14069
    Location:1 → 224
    STKc_Chk1; Catalytic domain of the Serine/Threonine kinase, Checkpoint kinase 1

  2. XM_038503846.1 → XP_038359774.1  serine/threonine-protein kinase Chk1 isoform X8

    UniProtKB/TrEMBL
    A0A8C0QZ09, A0A8C0Z0K6, A0A8I3NB92, A0A8P0SFN3
    Conserved Domains (1) summary
    cd14069
    Location:7 → 265
    STKc_Chk1; Catalytic domain of the Serine/Threonine kinase, Checkpoint kinase 1
Nucleotide Protein
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