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CAPN11 calpain 11 [ Canis lupus familiaris (dog) ]

Gene ID: 609624, updated on 5-Mar-2024

Summary

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Official Symbol
CAPN11provided by VGNC
Official Full Name
calpain 11provided by VGNC
Primary source
VGNC:VGNC:38700
See related
Ensembl:ENSCAFG00845011002
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 12
Exon count:
22
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 12 NC_051816.1 (13063224..13081793)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 12 NC_006594.4 (12607222..12625764)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 12 NC_049233.1 (12770497..12789068)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 12 NC_049272.1 (12588865..12607347)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 12 NC_049753.1 (12676546..12695304)

Chromosome 12 - NC_051816.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111098266 Neighboring gene mitochondrial ribosomal protein L14 Neighboring gene transmembrane protein 63B Neighboring gene uncharacterized LOC119874169 Neighboring gene myomixer, myoblast fusion factor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
calpain-11
XP_038347854.1
XP_038410119.1
XP_038473984.1
XP_038537923.1
XP_038539581.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051816.1 Reference ROS_Cfam_1.0

    Range
    13063224..13081793
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038683653.1 → XP_038539581.1  calpain-11

    UniProtKB/TrEMBL
    A0A8C0YUN1, A0A8I3NG54, A0A8I3NHE4, A0A8P0PM69
    Related
    ENSCAFP00845015302.1, ENSCAFT00845019564.1
    Conserved Domains (4) summary
    cd00214
    Location:365 → 525
    Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...
    cd15897
    Location:547 → 576
    EFh_PEF; EF-hand motif [structural motif]
    cl25352
    Location:547 → 716
    EFh_PEF; The penta-EF hand (PEF) family
    pfam00648
    Location:56 → 352
    Peptidase_C2; Calpain family cysteine protease

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049272.1 Alternate UMICH_Zoey_3.1

    Range
    12588865..12607347
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038491926.1 → XP_038347854.1  calpain-11

    Conserved Domains (4) summary
    cd00214
    Location:365 → 525
    Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...
    cd15897
    Location:547 → 576
    EFh_PEF; EF-hand motif [structural motif]
    cl25352
    Location:547 → 716
    EFh_PEF; The penta-EF hand (PEF) family
    pfam00648
    Location:56 → 352
    Peptidase_C2; Calpain family cysteine protease

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049753.1 Alternate UNSW_CanFamBas_1.0

    Range
    12676546..12695304
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038618056.1 → XP_038473984.1  calpain-11

    Conserved Domains (4) summary
    cd00214
    Location:365 → 525
    Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...
    cd15897
    Location:547 → 576
    EFh_PEF; EF-hand motif [structural motif]
    cl25352
    Location:547 → 716
    EFh_PEF; The penta-EF hand (PEF) family
    pfam00648
    Location:56 → 352
    Peptidase_C2; Calpain family cysteine protease

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049233.1 Alternate UU_Cfam_GSD_1.0

    Range
    12770497..12789068
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038554191.1 → XP_038410119.1  calpain-11

    UniProtKB/TrEMBL
    A0A8C0YUN1, A0A8I3NG54, A0A8I3NHE4, A0A8P0PM69
    Conserved Domains (4) summary
    cd00214
    Location:365 → 525
    Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...
    cd15897
    Location:547 → 576
    EFh_PEF; EF-hand motif [structural motif]
    cl25352
    Location:547 → 716
    EFh_PEF; The penta-EF hand (PEF) family
    pfam00648
    Location:56 → 352
    Peptidase_C2; Calpain family cysteine protease

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006594.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    12607222..12625764
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038681995.1 → XP_038537923.1  calpain-11

    UniProtKB/TrEMBL
    A0A8C0YUN1, A0A8I3NG54, A0A8I3NHE4, A0A8P0PM69
    Conserved Domains (4) summary
    cd00214
    Location:365 → 525
    Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...
    cd15897
    Location:547 → 576
    EFh_PEF; EF-hand motif [structural motif]
    cl25352
    Location:547 → 716
    EFh_PEF; The penta-EF hand (PEF) family
    pfam00648
    Location:56 → 352
    Peptidase_C2; Calpain family cysteine protease
Nucleotide Protein
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