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PNPLA3 patatin like phospholipase domain containing 3 [ Canis lupus familiaris (dog) ]

Gene ID: 609368, updated on 5-Mar-2024

Summary

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Official Symbol
PNPLA3provided by VGNC
Official Full Name
patatin like phospholipase domain containing 3provided by VGNC
Primary source
VGNC:VGNC:44754
See related
Ensembl:ENSCAFG00845012819
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
9
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 10 NC_051814.1 (22455884..22471128, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 10 NC_006592.4 (21647779..21663038, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 10 NC_049231.1 (22669488..22684748, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 10 NC_049270.1 (22175366..22190635, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 10 NC_049751.1 (22495689..22510929, complement)

Chromosome 10 - NC_051814.1Genomic Context describing neighboring genes Neighboring gene parvin beta Neighboring gene SAMM50 sorting and assembly machinery component Neighboring gene uncharacterized LOC119873615 Neighboring gene patatin like phospholipase domain containing 5 Neighboring gene uncharacterized LOC119873616 Neighboring gene sulfotransferase family 4A member 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-acylglycerol-3-phosphate O-acyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables triglyceride lipase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipid homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in triglyceride catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lipid droplet IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
patatin-like phospholipase domain-containing protein 3; 1-acylglycerol-3-phosphate O-acyltransferase PNPLA3; LOW QUALITY PROTEIN: 1-acylglycerol-3-phosphate O-acyltransferase PNPLA3
XP_038344293.1
XP_038406198.1
XP_038470181.1
XP_038493046.1
XP_038535520.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051814.1 Reference ROS_Cfam_1.0

    Range
    22455884..22471128 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038679592.1 → XP_038535520.1  1-acylglycerol-3-phosphate O-acyltransferase PNPLA3

    UniProtKB/TrEMBL
    A0A8C0SBR1, A0A8C0SCT2, A0A8I3NMZ7
    Related
    ENSCAFP00845017874.1, ENSCAFT00845022802.1
    Conserved Domains (1) summary
    cd07221
    Location:8 → 259
    Pat_PNPLA3; Patatin-like phospholipase domain containing protein 3

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049270.1 Alternate UMICH_Zoey_3.1

    Range
    22175366..22190635 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038488365.1 → XP_038344293.1  1-acylglycerol-3-phosphate O-acyltransferase PNPLA3

    Conserved Domains (1) summary
    cd07221
    Location:8 → 259
    Pat_PNPLA3; Patatin-like phospholipase domain containing protein 3

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049751.1 Alternate UNSW_CanFamBas_1.0

    Range
    22495689..22510929 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038614253.1 → XP_038470181.1  LOW QUALITY PROTEIN: 1-acylglycerol-3-phosphate O-acyltransferase PNPLA3

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049231.1 Alternate UU_Cfam_GSD_1.0

    Range
    22669488..22684748 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038550270.1 → XP_038406198.1  1-acylglycerol-3-phosphate O-acyltransferase PNPLA3

    UniProtKB/TrEMBL
    A0A8C0SBR1, A0A8C0SCT2, A0A8I3NMZ7
    Conserved Domains (1) summary
    cd07221
    Location:8 → 259
    Pat_PNPLA3; Patatin-like phospholipase domain containing protein 3

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006592.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    21647779..21663038 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038637118.1 → XP_038493046.1  1-acylglycerol-3-phosphate O-acyltransferase PNPLA3

    UniProtKB/TrEMBL
    A0A8C0SBR1, A0A8C0SCT2, A0A8I3NMZ7
    Conserved Domains (1) summary
    cd07221
    Location:8 → 259
    Pat_PNPLA3; Patatin-like phospholipase domain containing protein 3
Nucleotide Protein
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