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PTGES2 prostaglandin E synthase 2 [ Canis lupus familiaris (dog) ]

Gene ID: 609101, updated on 5-Mar-2024

Summary

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Official Symbol
PTGES2provided by VGNC
Official Full Name
prostaglandin E synthase 2provided by VGNC
Primary source
VGNC:VGNC:45146
See related
Ensembl:ENSCAFG00845029789
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 9
Exon count:
8
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (56265556..56271558)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (54538207..54543755)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (55431910..55437458)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (55025498..55031060)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (55340213..55345769)

Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene CDKN1A interacting zinc finger protein 1 Neighboring gene bublin coiled coil protein Neighboring gene 60S ribosomal protein L30-like Neighboring gene lipocalin 2 Neighboring gene solute carrier family 25 member 25 Neighboring gene uncharacterized LOC119873364 Neighboring gene nuclear apoptosis inducing factor 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables prostaglandin-E synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
prostaglandin E synthase 2
NP_001124522.1
XP_038531024.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001131050.1 → NP_001124522.1  prostaglandin E synthase 2

    See identical proteins and their annotated locations for NP_001124522.1

    Status: PROVISIONAL

    Source sequence(s)
    EU707923
    UniProtKB/TrEMBL
    A0A8C0SNP1, A0A8P0NL47, B4YY03, F1P9X4
    Related
    ENSCAFP00845041418.1, ENSCAFT00845052759.1
    Conserved Domains (2) summary
    cd03197
    Location:221 → 369
    GST_C_mPGES2; C-terminal, alpha helical domain of microsomal Prostaglandin E synthase Type 2
    cd03040
    Location:98 → 174
    GST_N_mPGES2; GST_N family; microsomal Prostaglandin E synthase Type 2 (mPGES2) subfamily; mPGES2 is a membrane-anchored dimeric protein containing a CXXC motif which catalyzes the isomerization of PGH2 to PGE2. Unlike cytosolic PGE synthase (cPGES) and microsomal ...

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051813.1 Reference ROS_Cfam_1.0

    Range
    56265556..56271558
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038675096.1 → XP_038531024.1  prostaglandin E synthase 2 isoform X1

    Conserved Domains (1) summary
    cd03197
    Location:33 → 181
    GST_C_mPGES2; C-terminal, alpha helical domain of microsomal Prostaglandin E synthase Type 2

RNA

  1. XR_005431692.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049269.1 Alternate UMICH_Zoey_3.1

    Range
    55025498..55031060
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

    Range
    55340213..55345769
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

    Range
    55431910..55437458
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    54538207..54543755
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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