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ITGB5 integrin subunit beta 5 [ Canis lupus familiaris (dog) ]

Gene ID: 608977, updated on 5-Mar-2024

Summary

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Official Symbol
ITGB5provided by VGNC
Official Full Name
integrin subunit beta 5provided by VGNC
Primary source
VGNC:VGNC:42140
See related
Ensembl:ENSCAFG00845026987
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 33
Exon count:
15
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 33 NC_051837.1 (28033980..28149103, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 33 NC_006615.4 (27820964..27935930, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 33 NC_049254.1 (28492316..28607994, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 33 NC_049293.1 (27829232..27945045, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 33 NC_049774.1 (27873552..27988833, complement)

Chromosome 33 - NC_051837.1Genomic Context describing neighboring genes Neighboring gene kalirin-like Neighboring gene uncharacterized LOC119867343 Neighboring gene uncharacterized LOC106558170 Neighboring gene uridine monophosphate synthetase Neighboring gene uncharacterized LOC119867344 Neighboring gene mucin 13, cell surface associated Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion mediated by integrin IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of integrin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
integrin beta-5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051837.1 Reference ROS_Cfam_1.0

    Range
    28033980..28149103 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038445194.1 → XP_038301122.1  integrin beta-5

    UniProtKB/TrEMBL
    A0A8C0JUW3, A0A8C0RMW5, A0A8I3QCJ7
    Related
    ENSCAFP00845037300.1, ENSCAFT00845047537.1
    Conserved Domains (5) summary
    smart00187
    Location:35 → 463
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07965
    Location:635 → 719
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:744 → 782
    Integrin_b_cyt; Integrin beta cytoplasmic domain
    pfam18372
    Location:465 → 493
    I-EGF_1; Integrin beta epidermal growth factor like domain 1
    NF033759
    Location:499 → 644
    exchanger_TraA; outer membrane exchange protein TraA

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049293.1 Alternate UMICH_Zoey_3.1

    Range
    27829232..27945045 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038519444.1 → XP_038375372.1  integrin beta-5

    Conserved Domains (5) summary
    smart00187
    Location:35 → 463
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07965
    Location:635 → 719
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:744 → 782
    Integrin_b_cyt; Integrin beta cytoplasmic domain
    pfam18372
    Location:465 → 493
    I-EGF_1; Integrin beta epidermal growth factor like domain 1
    NF033759
    Location:499 → 644
    exchanger_TraA; outer membrane exchange protein TraA

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049774.1 Alternate UNSW_CanFamBas_1.0

    Range
    27873552..27988833 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038647481.1 → XP_038503409.1  integrin beta-5

    Conserved Domains (5) summary
    smart00187
    Location:35 → 463
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07965
    Location:635 → 719
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:744 → 782
    Integrin_b_cyt; Integrin beta cytoplasmic domain
    pfam18372
    Location:465 → 493
    I-EGF_1; Integrin beta epidermal growth factor like domain 1
    NF033759
    Location:499 → 644
    exchanger_TraA; outer membrane exchange protein TraA

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049254.1 Alternate UU_Cfam_GSD_1.0

    Range
    28492316..28607994 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038583063.1 → XP_038438991.1  integrin beta-5

    UniProtKB/TrEMBL
    A0A8C0JUW3, A0A8C0RMW5, A0A8I3QCJ7
    Conserved Domains (5) summary
    smart00187
    Location:35 → 463
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07965
    Location:635 → 719
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:744 → 782
    Integrin_b_cyt; Integrin beta cytoplasmic domain
    pfam18372
    Location:465 → 493
    I-EGF_1; Integrin beta epidermal growth factor like domain 1
    NF033759
    Location:499 → 644
    exchanger_TraA; outer membrane exchange protein TraA

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006615.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    27820964..27935930 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_846152.5 → XP_851245.2  integrin beta-5

    UniProtKB/TrEMBL
    A0A8C0JUW3, A0A8C0RMW5, A0A8I3QCJ7
    Conserved Domains (5) summary
    smart00187
    Location:35 → 463
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07965
    Location:635 → 719
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:744 → 782
    Integrin_b_cyt; Integrin beta cytoplasmic domain
    pfam18372
    Location:465 → 493
    I-EGF_1; Integrin beta epidermal growth factor like domain 1
    NF033759
    Location:499 → 644
    exchanger_TraA; outer membrane exchange protein TraA
Nucleotide Protein
Heading Accession and Version

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