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EPN1 epsin 1 [ Canis lupus familiaris (dog) ]

Gene ID: 608964, updated on 5-Mar-2024

Summary

Official Symbol
EPN1provided by VGNC
Official Full Name
epsin 1provided by VGNC
Primary source
VGNC:VGNC:40419
See related
Ensembl:ENSCAFG00845000457
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

Location:
chromosome: 1
Exon count:
12
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 1 NC_051805.1 (102712494..102727183, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 1 NC_006583.4 (102116113..102130802, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 1 NC_049222.1 (102825037..102839725, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 1 NC_049261.1 (102350090..102364779, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 1 NC_049742.1 (102061977..102076667, complement)

Chromosome 1 - NC_051805.1Genomic Context describing neighboring genes Neighboring gene NLR family pyrin domain containing 9 Neighboring gene ret finger protein like 4A Neighboring gene U2 small nuclear RNA auxiliary factor 2 Neighboring gene coiled-coil domain containing 106

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables clathrin binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables phospholipid binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in endocytosis IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of clathrin vesicle coat IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in endosome IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051805.1 Reference ROS_Cfam_1.0

    Range
    102712494..102727183 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038655710.1XP_038511638.1  epsin-1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0QCZ8, A0A8I3MFJ4, A0A8P0PDX2
    Related
    ENSCAFP00845000540.1, ENSCAFT00845000737.1
    Conserved Domains (2) summary
    PRK07764
    Location:248406
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd16990
    Location:19142
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family
  2. XM_038655707.1XP_038511635.1  epsin-1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QFH2, A0A8I3MBG9, A0A8P0N5J8
    Conserved Domains (2) summary
    PRK07764
    Location:273431
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd16990
    Location:19142
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family
  3. XM_038655708.1XP_038511636.1  epsin-1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QFH2, A0A8I3MBG9, A0A8P0N5J8
    Related
    ENSCAFP00845000532.1, ENSCAFT00845000728.1
    Conserved Domains (2) summary
    PRK07764
    Location:273431
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd16990
    Location:19142
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family
  4. XM_038655709.1XP_038511637.1  epsin-1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QFH2, A0A8I3MBG9, A0A8P0N5J8
    Conserved Domains (2) summary
    PRK07764
    Location:273431
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd16990
    Location:19142
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049261.1 Alternate UMICH_Zoey_3.1

    Range
    102350090..102364779 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038466908.1XP_038322836.1  epsin-1 isoform X2

    Conserved Domains (2) summary
    PRK07764
    Location:248406
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd16990
    Location:19142
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family
  2. XM_038466905.1XP_038322833.1  epsin-1 isoform X1

    Conserved Domains (2) summary
    PRK07764
    Location:273431
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd16990
    Location:19142
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family
  3. XM_038466906.1XP_038322834.1  epsin-1 isoform X1

    Conserved Domains (2) summary
    PRK07764
    Location:273431
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd16990
    Location:19142
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family
  4. XM_038466907.1XP_038322835.1  epsin-1 isoform X1

    Conserved Domains (2) summary
    PRK07764
    Location:273431
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd16990
    Location:19142
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049742.1 Alternate UNSW_CanFamBas_1.0

    Range
    102061977..102076667 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038591987.1XP_038447915.1  epsin-1 isoform X2

    Conserved Domains (2) summary
    PRK07764
    Location:248406
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd16990
    Location:19142
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family
  2. XM_038591984.1XP_038447912.1  epsin-1 isoform X1

  3. XM_038591985.1XP_038447913.1  epsin-1 isoform X1

  4. XM_038591986.1XP_038447914.1  epsin-1 isoform X1

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049222.1 Alternate UU_Cfam_GSD_1.0

    Range
    102825037..102839725 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038527688.1XP_038383616.1  epsin-1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0QCZ8, A0A8I3MFJ4, A0A8P0PDX2
    Conserved Domains (2) summary
    PRK07764
    Location:248406
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd16990
    Location:19142
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family
  2. XM_038527685.1XP_038383613.1  epsin-1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QFH2, A0A8I3MBG9, A0A8P0N5J8
    Conserved Domains (2) summary
    PRK07764
    Location:273431
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd16990
    Location:19142
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family
  3. XM_038527686.1XP_038383614.1  epsin-1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QFH2, A0A8I3MBG9, A0A8P0N5J8
    Conserved Domains (2) summary
    PRK07764
    Location:273431
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd16990
    Location:19142
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family
  4. XM_038527687.1XP_038383615.1  epsin-1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QFH2, A0A8I3MBG9, A0A8P0N5J8
    Conserved Domains (2) summary
    PRK07764
    Location:273431
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd16990
    Location:19142
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    102116113..102130802 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005616104.4XP_005616161.1  epsin-1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0QCZ8, A0A8I3MFJ4, A0A8P0PDX2
    Conserved Domains (2) summary
    PRK07764
    Location:248406
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd16990
    Location:19142
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family
  2. XM_005616102.4XP_005616159.1  epsin-1 isoform X1

    See identical proteins and their annotated locations for XP_005616159.1

    UniProtKB/TrEMBL
    A0A8C0QFH2, A0A8I3MBG9, A0A8P0N5J8
    Conserved Domains (2) summary
    PRK07764
    Location:273431
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd16990
    Location:19142
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family
  3. XM_845641.7XP_850734.1  epsin-1 isoform X1

    See identical proteins and their annotated locations for XP_850734.1

    UniProtKB/TrEMBL
    A0A8C0QFH2, A0A8I3MBG9, A0A8P0N5J8
    Conserved Domains (2) summary
    PRK07764
    Location:273431
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd16990
    Location:19142
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family
  4. XM_005616103.4XP_005616160.1  epsin-1 isoform X1

    See identical proteins and their annotated locations for XP_005616160.1

    UniProtKB/TrEMBL
    A0A8C0QFH2, A0A8I3MBG9, A0A8P0N5J8
    Conserved Domains (2) summary
    PRK07764
    Location:273431
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd16990
    Location:19142
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family