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CDK7 cyclin dependent kinase 7 [ Canis lupus familiaris (dog) ]

Gene ID: 608441, updated on 5-Mar-2024

Summary

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Official Symbol
CDK7provided by VGNC
Official Full Name
cyclin dependent kinase 7provided by VGNC
Primary source
VGNC:VGNC:39060
See related
Ensembl:ENSCAFG00845012080
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
17
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 2 NC_051806.1 (54828202..54891625)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 2 NC_006584.4 (51283814..51347207)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 2 NC_049223.1 (53550125..53613994)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 2 NC_049262.1 (51887194..51950489)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 2 NC_049743.1 (52662280..52725915)

Chromosome 2 - NC_051806.1Genomic Context describing neighboring genes Neighboring gene centromere protein H Neighboring gene alpha-ketoglutarate dehydrogenase subunit 4 Neighboring gene ribosomal protein S3A pseudogene Neighboring gene U6 spliceosomal RNA Neighboring gene coiled-coil domain containing 125 Neighboring gene U2 spliceosomal RNA Neighboring gene adenylate kinase 6 Neighboring gene RAD17 checkpoint clamp loader component

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II CTD heptapeptide repeat kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cyclin-dependent protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of transcription factor TFIIH holo complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of transcription factor TFIIK complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cyclin-dependent kinase 7
Names
cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)
XP_038315961.1
XP_038315966.1
XP_038315971.1
XP_038315976.1
XP_038315977.1
XP_038315979.1
XP_038325902.1
XP_038325903.1
XP_038325904.1
XP_038325905.1
XP_038325906.1
XP_038325907.1
XP_038386709.1
XP_038386710.1
XP_038386711.1
XP_038386712.1
XP_038386714.1
XP_038386715.1
XP_038450931.1
XP_038450932.1
XP_038450933.1
XP_038450934.1
XP_038450935.1
XP_038450936.1
XP_038515007.1
XP_038515008.1
XP_038515009.1
XP_038515010.1
XP_038515011.1
XP_038515012.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051806.1 Reference ROS_Cfam_1.0

    Range
    54828202..54891625
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038659079.1 → XP_038515007.1  cyclin-dependent kinase 7 isoform X1

    Conserved Domains (1) summary
    cd07841
    Location:11 → 308
    STKc_CDK7; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 7

  2. XM_038659080.1 → XP_038515008.1  cyclin-dependent kinase 7 isoform X2

    UniProtKB/TrEMBL
    A0A8C0PZY8
    Conserved Domains (1) summary
    cd07841
    Location:11 → 308
    STKc_CDK7; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 7

  3. XM_038659081.1 → XP_038515009.1  cyclin-dependent kinase 7 isoform X3

    UniProtKB/TrEMBL
    A0A8C0PZY8
    Conserved Domains (1) summary
    cd07841
    Location:11 → 308
    STKc_CDK7; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 7

  4. XM_038659084.1 → XP_038515012.1  cyclin-dependent kinase 7 isoform X6

    UniProtKB/TrEMBL
    A0A8C0PZY8, A0A8I3NLD6, A0A8P0NA59
    Related
    ENSCAFP00845016951.1, ENSCAFT00845021568.1
    Conserved Domains (1) summary
    cd07841
    Location:11 → 308
    STKc_CDK7; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 7

  5. XM_038659082.1 → XP_038515010.1  cyclin-dependent kinase 7 isoform X4

    UniProtKB/TrEMBL
    A0A8C0M946, A0A8C0PZY8, A0A8I3RWW9
    Related
    ENSCAFP00845016919.1, ENSCAFT00845021529.1
    Conserved Domains (1) summary
    cd07841
    Location:11 → 308
    STKc_CDK7; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 7

  6. XM_038659083.1 → XP_038515011.1  cyclin-dependent kinase 7 isoform X5

    Conserved Domains (1) summary
    cd07841
    Location:1 → 215
    STKc_CDK7; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 7

RNA

  1. XR_005423249.1 RNA Sequence

  2. XR_005423250.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049262.1 Alternate UMICH_Zoey_3.1

    Range
    51887194..51950489
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038469974.1 → XP_038325902.1  cyclin-dependent kinase 7 isoform X1

    Conserved Domains (1) summary
    cd07841
    Location:11 → 308
    STKc_CDK7; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 7

  2. XM_038469975.1 → XP_038325903.1  cyclin-dependent kinase 7 isoform X2

    Conserved Domains (1) summary
    cd07841
    Location:11 → 308
    STKc_CDK7; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 7

  3. XM_038469976.1 → XP_038325904.1  cyclin-dependent kinase 7 isoform X3

    Conserved Domains (1) summary
    cd07841
    Location:11 → 308
    STKc_CDK7; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 7

  4. XM_038469979.1 → XP_038325907.1  cyclin-dependent kinase 7 isoform X6

    Conserved Domains (1) summary
    cd07841
    Location:11 → 308
    STKc_CDK7; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 7

  5. XM_038469977.1 → XP_038325905.1  cyclin-dependent kinase 7 isoform X4

    Conserved Domains (1) summary
    cd07841
    Location:11 → 308
    STKc_CDK7; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 7

  6. XM_038469978.1 → XP_038325906.1  cyclin-dependent kinase 7 isoform X5

    Conserved Domains (1) summary
    cd07841
    Location:1 → 215
    STKc_CDK7; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 7

RNA

  1. XR_005322054.1 RNA Sequence

  2. XR_005322055.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049743.1 Alternate UNSW_CanFamBas_1.0

    Range
    52662280..52725915
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038595003.1 → XP_038450931.1  cyclin-dependent kinase 7 isoform X1

    Conserved Domains (1) summary
    cd07841
    Location:11 → 308
    STKc_CDK7; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 7

  2. XM_038595004.1 → XP_038450932.1  cyclin-dependent kinase 7 isoform X2

    Conserved Domains (1) summary
    cd07841
    Location:11 → 308
    STKc_CDK7; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 7

  3. XM_038595005.1 → XP_038450933.1  cyclin-dependent kinase 7 isoform X3

    Conserved Domains (1) summary
    cd07841
    Location:11 → 308
    STKc_CDK7; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 7

  4. XM_038595008.1 → XP_038450936.1  cyclin-dependent kinase 7 isoform X6

    Conserved Domains (1) summary
    cd07841
    Location:11 → 308
    STKc_CDK7; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 7

  5. XM_038595006.1 → XP_038450934.1  cyclin-dependent kinase 7 isoform X4

    Conserved Domains (1) summary
    cd07841
    Location:11 → 308
    STKc_CDK7; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 7

  6. XM_038595007.1 → XP_038450935.1  cyclin-dependent kinase 7 isoform X5

    Conserved Domains (1) summary
    cd07841
    Location:1 → 215
    STKc_CDK7; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 7

RNA

  1. XR_005390219.1 RNA Sequence

  2. XR_005390220.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049223.1 Alternate UU_Cfam_GSD_1.0

    Range
    53550125..53613994
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038530781.1 → XP_038386709.1  cyclin-dependent kinase 7 isoform X1

    Conserved Domains (1) summary
    cd07841
    Location:11 → 308
    STKc_CDK7; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 7

  2. XM_038530782.1 → XP_038386710.1  cyclin-dependent kinase 7 isoform X2

    UniProtKB/TrEMBL
    A0A8C0PZY8
    Conserved Domains (1) summary
    cd07841
    Location:11 → 308
    STKc_CDK7; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 7

  3. XM_038530783.1 → XP_038386711.1  cyclin-dependent kinase 7 isoform X3

    UniProtKB/TrEMBL
    A0A8C0PZY8
    Conserved Domains (1) summary
    cd07841
    Location:11 → 308
    STKc_CDK7; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 7

  4. XM_038530787.1 → XP_038386715.1  cyclin-dependent kinase 7 isoform X6

    UniProtKB/TrEMBL
    A0A8C0PZY8, A0A8I3NLD6, A0A8P0NA59
    Conserved Domains (1) summary
    cd07841
    Location:11 → 308
    STKc_CDK7; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 7

  5. XM_038530784.1 → XP_038386712.1  cyclin-dependent kinase 7 isoform X4

    UniProtKB/TrEMBL
    A0A8C0M946, A0A8C0PZY8, A0A8I3RWW9
    Conserved Domains (1) summary
    cd07841
    Location:11 → 308
    STKc_CDK7; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 7

  6. XM_038530786.1 → XP_038386714.1  cyclin-dependent kinase 7 isoform X5

    Conserved Domains (1) summary
    cd07841
    Location:1 → 215
    STKc_CDK7; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 7

RNA

  1. XR_005355648.1 RNA Sequence

  2. XR_005355649.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006584.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    51283814..51347207
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038460033.1 → XP_038315961.1  cyclin-dependent kinase 7 isoform X1

    Conserved Domains (1) summary
    cd07841
    Location:11 → 308
    STKc_CDK7; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 7

  2. XM_038460038.1 → XP_038315966.1  cyclin-dependent kinase 7 isoform X2

    UniProtKB/TrEMBL
    A0A8C0PZY8
    Conserved Domains (1) summary
    cd07841
    Location:11 → 308
    STKc_CDK7; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 7

  3. XM_038460043.1 → XP_038315971.1  cyclin-dependent kinase 7 isoform X3

    UniProtKB/TrEMBL
    A0A8C0PZY8
    Conserved Domains (1) summary
    cd07841
    Location:11 → 308
    STKc_CDK7; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 7

  4. XM_038460051.1 → XP_038315979.1  cyclin-dependent kinase 7 isoform X6

    UniProtKB/TrEMBL
    A0A8C0PZY8, A0A8I3NLD6, A0A8P0NA59
    Conserved Domains (1) summary
    cd07841
    Location:11 → 308
    STKc_CDK7; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 7

  5. XM_038460048.1 → XP_038315976.1  cyclin-dependent kinase 7 isoform X4

    UniProtKB/TrEMBL
    A0A8C0M946, A0A8C0PZY8, A0A8I3RWW9
    Conserved Domains (1) summary
    cd07841
    Location:11 → 308
    STKc_CDK7; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 7

  6. XM_038460049.1 → XP_038315977.1  cyclin-dependent kinase 7 isoform X5

    Conserved Domains (1) summary
    cd07841
    Location:1 → 215
    STKc_CDK7; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 7

RNA

  1. XR_005315573.1 RNA Sequence

  2. XR_005315574.1 RNA Sequence

Nucleotide Protein
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