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BUB1B BUB1 mitotic checkpoint serine/threonine kinase B [ Canis lupus familiaris (dog) ]

Gene ID: 608350, updated on 5-Mar-2024

Summary

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Official Symbol
BUB1Bprovided by VGNC
Official Full Name
BUB1 mitotic checkpoint serine/threonine kinase Bprovided by VGNC
Primary source
VGNC:VGNC:38566
See related
Ensembl:ENSCAFG00845027328
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See BUB1B in Genome Data Viewer
Location:
chromosome: 30
Exon count:
23
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 30 NC_051834.1 (7490487..7538685)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 30 NC_006612.4 (7416730..7464873)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 30 NC_049251.1 (7647445..7695793)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 30 NC_049290.1 (7412929..7461263)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 30 NC_049771.1 (7519268..7567181)

Chromosome 30 - NC_051834.1Genomic Context describing neighboring genes Neighboring gene signal recognition particle 14 Neighboring gene Bcl2 modifying factor Neighboring gene uncharacterized LOC102157096 Neighboring gene p21 (RAC1) activated kinase 6 Neighboring gene ankyrin repeat domain 63

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in meiotic sister chromatid cohesion, centromeric IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitotic spindle assembly checkpoint signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mitotic checkpoint serine/threonine-protein kinase BUB1 beta
Names
BUB1 budding uninhibited by benzimidazoles 1 homolog beta
budding uninhibited by benzimidazoles 1 homolog beta
XP_005638296.1
XP_038297882.1
XP_038297883.1
XP_038372369.1
XP_038372370.1
XP_038435958.1
XP_038435959.1
XP_038500232.1
XP_038500233.1
XP_850443.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051834.1 Reference ROS_Cfam_1.0

    Range
    7490487..7538685
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038441954.1 → XP_038297882.1  mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform X1

    UniProtKB/TrEMBL
    A0A8I3PXH1, A0A8P0SDX3
    Related
    ENSCAFP00845037791.1, ENSCAFT00845048179.1
    Conserved Domains (3) summary
    COG1340
    Location:374 → 480
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    pfam08311
    Location:58 → 179
    Mad3_BUB1_I; Mad3/BUB1 homology region 1
    cl21453
    Location:752 → 1046
    PKc_like; Protein Kinases, catalytic domain

  2. XM_038441955.1 → XP_038297883.1  mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform X2

    UniProtKB/TrEMBL
    A0A8P0SDX3
    Conserved Domains (3) summary
    COG1340
    Location:374 → 480
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    pfam08311
    Location:58 → 179
    Mad3_BUB1_I; Mad3/BUB1 homology region 1
    cl21453
    Location:751 → 1045
    PKc_like; Protein Kinases, catalytic domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049290.1 Alternate UMICH_Zoey_3.1

    Range
    7412929..7461263
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038516441.1 → XP_038372369.1  mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform X3

    Conserved Domains (3) summary
    COG1340
    Location:374 → 480
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    pfam08311
    Location:58 → 179
    Mad3_BUB1_I; Mad3/BUB1 homology region 1
    cl21453
    Location:752 → 1046
    PKc_like; Protein Kinases, catalytic domain

  2. XM_038516442.1 → XP_038372370.1  mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform X4

    Conserved Domains (3) summary
    COG1340
    Location:374 → 480
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    pfam08311
    Location:58 → 179
    Mad3_BUB1_I; Mad3/BUB1 homology region 1
    cl21453
    Location:751 → 1045
    PKc_like; Protein Kinases, catalytic domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049771.1 Alternate UNSW_CanFamBas_1.0

    Range
    7519268..7567181
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038644304.1 → XP_038500232.1  mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform X1

    Conserved Domains (3) summary
    COG1340
    Location:374 → 480
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    pfam08311
    Location:58 → 179
    Mad3_BUB1_I; Mad3/BUB1 homology region 1
    cl21453
    Location:752 → 1046
    PKc_like; Protein Kinases, catalytic domain

  2. XM_038644305.1 → XP_038500233.1  mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform X2

    Conserved Domains (3) summary
    COG1340
    Location:374 → 480
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    pfam08311
    Location:58 → 179
    Mad3_BUB1_I; Mad3/BUB1 homology region 1
    cl21453
    Location:751 → 1045
    PKc_like; Protein Kinases, catalytic domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049251.1 Alternate UU_Cfam_GSD_1.0

    Range
    7647445..7695793
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038580030.1 → XP_038435958.1  mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform X5

    UniProtKB/TrEMBL
    A0A8I3PXH1, A0A8P0SDX3
    Conserved Domains (3) summary
    COG1340
    Location:374 → 480
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    pfam08311
    Location:58 → 179
    Mad3_BUB1_I; Mad3/BUB1 homology region 1
    cl21453
    Location:752 → 1046
    PKc_like; Protein Kinases, catalytic domain

  2. XM_038580031.1 → XP_038435959.1  mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform X6

    UniProtKB/TrEMBL
    A0A8P0SDX3
    Conserved Domains (3) summary
    COG1340
    Location:374 → 480
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    pfam08311
    Location:58 → 179
    Mad3_BUB1_I; Mad3/BUB1 homology region 1
    cl21453
    Location:751 → 1045
    PKc_like; Protein Kinases, catalytic domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006612.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    7416730..7464873
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005638239.4 → XP_005638296.1  mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform X1

    UniProtKB/TrEMBL
    A0A8I3PXH1, A0A8P0SDX3
    Conserved Domains (3) summary
    COG1340
    Location:374 → 480
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    pfam08311
    Location:58 → 179
    Mad3_BUB1_I; Mad3/BUB1 homology region 1
    cl21453
    Location:752 → 1046
    PKc_like; Protein Kinases, catalytic domain

  2. XM_845350.6 → XP_850443.2  mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform X2

    UniProtKB/TrEMBL
    A0A8P0SDX3
    Conserved Domains (3) summary
    COG1340
    Location:374 → 480
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    pfam08311
    Location:58 → 179
    Mad3_BUB1_I; Mad3/BUB1 homology region 1
    cl21453
    Location:751 → 1045
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
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