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ITGA10 integrin subunit alpha 10 [ Canis lupus familiaris (dog) ]

Gene ID: 608287, updated on 5-Mar-2024

Summary

Official Symbol
ITGA10provided by VGNC
Official Full Name
integrin subunit alpha 10provided by VGNC
Primary source
VGNC:VGNC:42121
See related
Ensembl:ENSCAFG00845010945
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

Location:
chromosome: 17
Exon count:
30
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 17 NC_051821.1 (59692674..59709253, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 17 NC_006599.4 (58163867..58180435, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 17 NC_049238.1 (59352967..59369541, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 17 NC_049277.1 (58565413..58581987, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 17 NC_049758.1 (58626550..58643124, complement)

Chromosome 17 - NC_051821.1Genomic Context describing neighboring genes Neighboring gene nudix hydrolase 17 Neighboring gene protein inhibitor of activated STAT 3 Neighboring gene ankyrin repeat domain 35 Neighboring gene peroxisomal biogenesis factor 11 beta Neighboring gene gonadotropin releasing hormone receptor 2 (pseudogene) Neighboring gene RNA binding motif protein 8A Neighboring gene limb and CNS expressed 1 like

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables integrin binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cell adhesion mediated by integrin IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
part_of integrin complex IEA
Inferred from Electronic Annotation
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051821.1 Reference ROS_Cfam_1.0

    Range
    59692674..59709253 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038422976.1XP_038278904.1  integrin alpha-10 isoform X4

    UniProtKB/TrEMBL
    A0A8C0QPA9
    Related
    ENSCAFP00845015317.1, ENSCAFT00845019583.1
    Conserved Domains (3) summary
    smart00191
    Location:548602
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:169349
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:6451051
    Integrin_alpha2; Integrin alpha
  2. XM_038422974.1XP_038278902.1  integrin alpha-10 isoform X2

    UniProtKB/TrEMBL
    A0A8C0QPA9
    Conserved Domains (3) summary
    smart00191
    Location:547601
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:169349
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:6441050
    Integrin_alpha2; Integrin alpha
  3. XM_038422973.1XP_038278901.1  integrin alpha-10 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QPA9
    Conserved Domains (3) summary
    smart00191
    Location:548602
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:169349
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:6451051
    Integrin_alpha2; Integrin alpha
  4. XM_038422975.1XP_038278903.1  integrin alpha-10 isoform X3

    UniProtKB/TrEMBL
    A0A8C0L629, A0A8C0QEX0, A0A8C0QPA9, A0A8I3RW71
    Related
    ENSCAFP00845015187.1, ENSCAFT00845019425.1
    Conserved Domains (3) summary
    smart00191
    Location:545599
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:166346
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:6421048
    Integrin_alpha2; Integrin alpha
  5. XM_038422977.1XP_038278905.1  integrin alpha-10 isoform X5

    UniProtKB/TrEMBL
    A0A8C0QPA9
    Conserved Domains (3) summary
    smart00191
    Location:414468
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:35215
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:511917
    Integrin_alpha2; Integrin alpha

RNA

  1. XR_005295808.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049277.1 Alternate UMICH_Zoey_3.1

    Range
    58565413..58581987 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038499460.1XP_038355388.1  integrin alpha-10 isoform X4

    Conserved Domains (3) summary
    smart00191
    Location:548602
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:169349
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:6451051
    Integrin_alpha2; Integrin alpha
  2. XM_038499458.1XP_038355386.1  integrin alpha-10 isoform X2

    Conserved Domains (3) summary
    smart00191
    Location:547601
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:169349
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:6441050
    Integrin_alpha2; Integrin alpha
  3. XM_038499457.1XP_038355385.1  integrin alpha-10 isoform X1

    Conserved Domains (3) summary
    smart00191
    Location:548602
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:169349
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:6451051
    Integrin_alpha2; Integrin alpha
  4. XM_038499459.1XP_038355387.1  integrin alpha-10 isoform X3

    Conserved Domains (3) summary
    smart00191
    Location:545599
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:166346
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:6421048
    Integrin_alpha2; Integrin alpha
  5. XM_038499461.1XP_038355389.1  integrin alpha-10 isoform X5

    Conserved Domains (3) summary
    smart00191
    Location:414468
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:35215
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:511917
    Integrin_alpha2; Integrin alpha

RNA

  1. XR_005338909.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049758.1 Alternate UNSW_CanFamBas_1.0

    Range
    58626550..58643124 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038626122.1XP_038482050.1  integrin alpha-10 isoform X4

    Conserved Domains (3) summary
    smart00191
    Location:548602
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:169349
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:6451051
    Integrin_alpha2; Integrin alpha
  2. XM_038626119.1XP_038482047.1  integrin alpha-10 isoform X2

    Conserved Domains (3) summary
    smart00191
    Location:547601
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:169349
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:6441050
    Integrin_alpha2; Integrin alpha
  3. XM_038626118.1XP_038482046.1  integrin alpha-10 isoform X1

    Conserved Domains (3) summary
    smart00191
    Location:548602
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:169349
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:6451051
    Integrin_alpha2; Integrin alpha
  4. XM_038626121.1XP_038482049.1  integrin alpha-10 isoform X3

    Conserved Domains (3) summary
    smart00191
    Location:545599
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:166346
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:6421048
    Integrin_alpha2; Integrin alpha
  5. XM_038626123.1XP_038482051.1  integrin alpha-10 isoform X5

    Conserved Domains (3) summary
    smart00191
    Location:414468
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:35215
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:511917
    Integrin_alpha2; Integrin alpha

RNA

  1. XR_005406800.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049238.1 Alternate UU_Cfam_GSD_1.0

    Range
    59352967..59369541 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038562036.1XP_038417964.1  integrin alpha-10 isoform X4

    UniProtKB/TrEMBL
    A0A8C0QPA9
    Conserved Domains (3) summary
    smart00191
    Location:548602
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:169349
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:6451051
    Integrin_alpha2; Integrin alpha
  2. XM_038562034.1XP_038417962.1  integrin alpha-10 isoform X2

    UniProtKB/TrEMBL
    A0A8C0QPA9
    Conserved Domains (3) summary
    smart00191
    Location:547601
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:169349
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:6441050
    Integrin_alpha2; Integrin alpha
  3. XM_038562033.1XP_038417961.1  integrin alpha-10 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QPA9
    Conserved Domains (3) summary
    smart00191
    Location:548602
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:169349
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:6451051
    Integrin_alpha2; Integrin alpha
  4. XM_038562035.1XP_038417963.1  integrin alpha-10 isoform X3

    UniProtKB/TrEMBL
    A0A8C0L629, A0A8C0QEX0, A0A8C0QPA9, A0A8I3RW71
    Conserved Domains (3) summary
    smart00191
    Location:545599
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:166346
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:6421048
    Integrin_alpha2; Integrin alpha
  5. XM_038562037.1XP_038417965.1  integrin alpha-10 isoform X5

    UniProtKB/TrEMBL
    A0A8C0QPA9
    Conserved Domains (3) summary
    smart00191
    Location:414468
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:35215
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:511917
    Integrin_alpha2; Integrin alpha

RNA

  1. XR_005372708.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006599.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    58163867..58180435 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038453439.1XP_038309367.1  integrin alpha-10 isoform X2

    UniProtKB/TrEMBL
    A0A8C0QPA9
    Conserved Domains (3) summary
    smart00191
    Location:547601
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:169349
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:6441050
    Integrin_alpha2; Integrin alpha
  2. XM_038453440.1XP_038309368.1  integrin alpha-10 isoform X4

    UniProtKB/TrEMBL
    A0A8C0QPA9
    Conserved Domains (3) summary
    smart00191
    Location:548602
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:169349
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:6451051
    Integrin_alpha2; Integrin alpha
  3. XM_845262.5XP_850355.1  integrin alpha-10 isoform X3

    UniProtKB/TrEMBL
    A0A8C0L629, A0A8C0QEX0, A0A8C0QPA9, A0A8I3RW71
    Conserved Domains (3) summary
    smart00191
    Location:545599
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:166346
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:6421048
    Integrin_alpha2; Integrin alpha
  4. XM_038453438.1XP_038309366.1  integrin alpha-10 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QPA9
    Conserved Domains (3) summary
    smart00191
    Location:548602
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:169349
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:6451051
    Integrin_alpha2; Integrin alpha
  5. XM_014120580.3XP_013976055.1  integrin alpha-10 isoform X5

    UniProtKB/TrEMBL
    A0A8C0QPA9
    Conserved Domains (3) summary
    smart00191
    Location:414468
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:35215
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:511917
    Integrin_alpha2; Integrin alpha

RNA

  1. XR_005311297.1 RNA Sequence