U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

FAF1 Fas associated factor 1 [ Canis lupus familiaris (dog) ]

Gene ID: 608231, updated on 5-Mar-2024

Summary

Official Symbol
FAF1provided by VGNC
Official Full Name
Fas associated factor 1provided by VGNC
Primary source
VGNC:VGNC:40567
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Location:
chromosome: 15
Exon count:
20
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 15 NC_051819.1 (10361829..10827913)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 15 NC_006597.4 (10381228..10841837)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 15 NC_049236.1 (10272462..10733482)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 15 NC_049275.1 (10167164..10628188)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 15 NC_049756.1 (10255573..10716512)

Chromosome 15 - NC_051819.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119869374 Neighboring gene uncharacterized LOC119881739 Neighboring gene cyclin dependent kinase inhibitor 2C Neighboring gene MICOS complex subunit MIC26-like Neighboring gene polyadenylate-binding protein-interacting protein 1-like Neighboring gene ATPase inhibitor, mitochondrial-like Neighboring gene serine/arginine-rich splicing factor 7-like Neighboring gene DMRT like family A2 Neighboring gene uncharacterized LOC119869345

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NF-kappaB binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables ubiquitin binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051819.1 Reference ROS_Cfam_1.0

    Range
    10361829..10827913
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038687304.1XP_038543232.1  FAS-associated factor 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KL48
    Conserved Domains (6) summary
    cd02990
    Location:368503
    UAS_FAF1; UAS family, FAS-associated factor 1 (FAF1) subfamily; FAF1 contains a UAS domain of unknown function N-terminal to a ubiquitin-associated UBX domain. FAF1 also contains ubiquitin-associated UBA and nuclear targeting domains, N-terminal to the UAS domain. ...
    cd14413
    Location:1141
    UBA_FAF1; UBA-like domain found in FAS-associated factor 1 (FAF1) and similar proteins
    cd01771
    Location:587665
    UBX_UBXN3A; Ubiquitin regulatory domain X (UBX) found in FAS associated factor 1 (FAF1, also known as UBXN3A) and similar proteins
    cd17056
    Location:236284
    Ubl_FAF1; ubiquitin-like (Ubl) domain found in FAS-associated factor 1 (FAF1) and similar proteins
    cd17129
    Location:94166
    Ubl1_FAF1; ubiquitin-like (Ubl) domain 1 found in FAS-associated factor 1 (FAF1) and similar proteins
    pfam09731
    Location:506614
    Mitofilin; Mitochondrial inner membrane protein

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049275.1 Alternate UMICH_Zoey_3.1

    Range
    10167164..10628188
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038495705.1XP_038351633.1  FAS-associated factor 1 isoform X2

    Conserved Domains (6) summary
    cd02990
    Location:346481
    UAS_FAF1; UAS family, FAS-associated factor 1 (FAF1) subfamily; FAF1 contains a UAS domain of unknown function N-terminal to a ubiquitin-associated UBX domain. FAF1 also contains ubiquitin-associated UBA and nuclear targeting domains, N-terminal to the UAS domain. ...
    cd14413
    Location:1141
    UBA_FAF1; UBA-like domain found in FAS-associated factor 1 (FAF1) and similar proteins
    cd01771
    Location:565643
    UBX_UBXN3A; Ubiquitin regulatory domain X (UBX) found in FAS associated factor 1 (FAF1, also known as UBXN3A) and similar proteins
    cd17056
    Location:189262
    Ubl_FAF1; ubiquitin-like (Ubl) domain found in FAS-associated factor 1 (FAF1) and similar proteins
    cd17129
    Location:94166
    Ubl1_FAF1; ubiquitin-like (Ubl) domain 1 found in FAS-associated factor 1 (FAF1) and similar proteins
    pfam09731
    Location:484592
    Mitofilin; Mitochondrial inner membrane protein
  2. XM_038495706.1XP_038351634.1  FAS-associated factor 1 isoform X3

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049756.1 Alternate UNSW_CanFamBas_1.0

    Range
    10255573..10716512
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038621946.1XP_038477874.1  FAS-associated factor 1 isoform X4

    Conserved Domains (6) summary
    cd02990
    Location:346481
    UAS_FAF1; UAS family, FAS-associated factor 1 (FAF1) subfamily; FAF1 contains a UAS domain of unknown function N-terminal to a ubiquitin-associated UBX domain. FAF1 also contains ubiquitin-associated UBA and nuclear targeting domains, N-terminal to the UAS domain. ...
    cd14413
    Location:1141
    UBA_FAF1; UBA-like domain found in FAS-associated factor 1 (FAF1) and similar proteins
    cd01771
    Location:565643
    UBX_UBXN3A; Ubiquitin regulatory domain X (UBX) found in FAS associated factor 1 (FAF1, also known as UBXN3A) and similar proteins
    cd17056
    Location:189262
    Ubl_FAF1; ubiquitin-like (Ubl) domain found in FAS-associated factor 1 (FAF1) and similar proteins
    cd17129
    Location:94166
    Ubl1_FAF1; ubiquitin-like (Ubl) domain 1 found in FAS-associated factor 1 (FAF1) and similar proteins
    pfam09731
    Location:484592
    Mitofilin; Mitochondrial inner membrane protein
  2. XM_038621947.1XP_038477875.1  FAS-associated factor 1 isoform X5

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049236.1 Alternate UU_Cfam_GSD_1.0

    Range
    10272462..10733482
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038558075.1XP_038414003.1  FAS-associated factor 1 isoform X6

    UniProtKB/TrEMBL
    A0A8C0KL48
    Conserved Domains (6) summary
    cd02990
    Location:346481
    UAS_FAF1; UAS family, FAS-associated factor 1 (FAF1) subfamily; FAF1 contains a UAS domain of unknown function N-terminal to a ubiquitin-associated UBX domain. FAF1 also contains ubiquitin-associated UBA and nuclear targeting domains, N-terminal to the UAS domain. ...
    cd14413
    Location:1141
    UBA_FAF1; UBA-like domain found in FAS-associated factor 1 (FAF1) and similar proteins
    cd01771
    Location:565643
    UBX_UBXN3A; Ubiquitin regulatory domain X (UBX) found in FAS associated factor 1 (FAF1, also known as UBXN3A) and similar proteins
    cd17056
    Location:189262
    Ubl_FAF1; ubiquitin-like (Ubl) domain found in FAS-associated factor 1 (FAF1) and similar proteins
    cd17129
    Location:94166
    Ubl1_FAF1; ubiquitin-like (Ubl) domain 1 found in FAS-associated factor 1 (FAF1) and similar proteins
    pfam09731
    Location:484592
    Mitofilin; Mitochondrial inner membrane protein
  2. XM_038558076.1XP_038414004.1  FAS-associated factor 1 isoform X7

    UniProtKB/TrEMBL
    A0A8C0KL48, A0A8C0MM58, A0A8P0NR35

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006597.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    10381228..10841837
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038452059.1XP_038307987.1  FAS-associated factor 1 isoform X8

    UniProtKB/TrEMBL
    A0A8C0KL48
    Conserved Domains (6) summary
    cd02990
    Location:346481
    UAS_FAF1; UAS family, FAS-associated factor 1 (FAF1) subfamily; FAF1 contains a UAS domain of unknown function N-terminal to a ubiquitin-associated UBX domain. FAF1 also contains ubiquitin-associated UBA and nuclear targeting domains, N-terminal to the UAS domain. ...
    cd14413
    Location:1141
    UBA_FAF1; UBA-like domain found in FAS-associated factor 1 (FAF1) and similar proteins
    cd01771
    Location:565643
    UBX_UBXN3A; Ubiquitin regulatory domain X (UBX) found in FAS associated factor 1 (FAF1, also known as UBXN3A) and similar proteins
    cd17056
    Location:189262
    Ubl_FAF1; ubiquitin-like (Ubl) domain found in FAS-associated factor 1 (FAF1) and similar proteins
    cd17129
    Location:94166
    Ubl1_FAF1; ubiquitin-like (Ubl) domain 1 found in FAS-associated factor 1 (FAF1) and similar proteins
    pfam09731
    Location:484592
    Mitofilin; Mitochondrial inner membrane protein
  2. XM_844729.6XP_849822.1  FAS-associated factor 1 isoform X9

    UniProtKB/TrEMBL
    A0A8C0KL48, A0A8C0MM58, A0A8P0NR35
    Conserved Domains (4) summary
    cd01771
    Location:569648
    Faf1_UBX; Faf1 UBX domain
    cd02990
    Location:351486
    UAS_FAF1; UAS family, FAS-associated factor 1 (FAF1) subfamily; FAF1 contains a UAS domain of unknown function N-terminal to a ubiquitin-associated UBX domain. FAF1 also contains ubiquitin-associated UBA and nuclear targeting domains, N-terminal to the UAS domain. ...
    cd14413
    Location:1446
    UBA_FAF1; UBA-like domain found in FAS-associated factor 1 (FAF1) and similar proteins
    pfam09731
    Location:489594
    Mitofilin; Mitochondrial inner membrane protein