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SQLE squalene epoxidase [ Canis lupus familiaris (dog) ]

Gene ID: 608021, updated on 5-Mar-2024

Summary

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Official Symbol
SQLEprovided by VGNC
Official Full Name
squalene epoxidaseprovided by VGNC
Primary source
VGNC:VGNC:46786
See related
Ensembl:ENSCAFG00845012036
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See SQLE in Genome Data Viewer
Location:
chromosome: 13
Exon count:
12
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 13 NC_051817.1 (23335721..23359940)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 13 NC_006595.4 (22958181..22982327)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 13 NC_049234.1 (23408709..23432884)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 13 NC_049273.1 (23056318..23080692)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 13 NC_049754.1 (23165695..23189887)

Chromosome 13 - NC_051817.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102156610 Neighboring gene zinc finger protein 572 Neighboring gene WASH complex subunit 5 Neighboring gene NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase Neighboring gene uncharacterized LOC111098547

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables squalene monooxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cholesterol metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sterol biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
squalene monooxygenase
XP_005627990.1
XP_005627991.1
XP_038349159.1
XP_038349160.1
XP_038411425.1
XP_038411426.1
XP_038475324.1
XP_038475325.1
XP_038540932.1
XP_038540933.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051817.1 Reference ROS_Cfam_1.0

    Range
    23335721..23359940
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038685005.1 → XP_038540933.1  squalene monooxygenase

    UniProtKB/TrEMBL
    A0A8C0K1C6, A0A8C0MWQ3, A0A8C0SV77, A0A8I3NFI4
    Related
    ENSCAFP00845016852.1, ENSCAFT00845021443.1
    Conserved Domains (2) summary
    PRK07045
    Location:121 → 426
    PRK07045; putative monooxygenase; Reviewed
    cl21454
    Location:276 → 547
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  2. XM_038685004.1 → XP_038540932.1  squalene monooxygenase

    UniProtKB/TrEMBL
    A0A8C0K1C6, A0A8C0MWQ3, A0A8C0SV77, A0A8I3NFI4
    Conserved Domains (2) summary
    PRK07045
    Location:121 → 426
    PRK07045; putative monooxygenase; Reviewed
    cl21454
    Location:276 → 547
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049273.1 Alternate UMICH_Zoey_3.1

    Range
    23056318..23080692
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038493232.1 → XP_038349160.1  squalene monooxygenase

    Conserved Domains (2) summary
    PRK07045
    Location:121 → 426
    PRK07045; putative monooxygenase; Reviewed
    cl21454
    Location:276 → 547
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  2. XM_038493231.1 → XP_038349159.1  squalene monooxygenase

    Conserved Domains (2) summary
    PRK07045
    Location:121 → 426
    PRK07045; putative monooxygenase; Reviewed
    cl21454
    Location:276 → 547
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049754.1 Alternate UNSW_CanFamBas_1.0

    Range
    23165695..23189887
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038619397.1 → XP_038475325.1  squalene monooxygenase

    Conserved Domains (2) summary
    PRK07045
    Location:121 → 426
    PRK07045; putative monooxygenase; Reviewed
    cl21454
    Location:276 → 547
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  2. XM_038619396.1 → XP_038475324.1  squalene monooxygenase

    Conserved Domains (2) summary
    PRK07045
    Location:121 → 426
    PRK07045; putative monooxygenase; Reviewed
    cl21454
    Location:276 → 547
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049234.1 Alternate UU_Cfam_GSD_1.0

    Range
    23408709..23432884
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038555498.1 → XP_038411426.1  squalene monooxygenase

    UniProtKB/TrEMBL
    A0A8C0K1C6, A0A8C0MWQ3, A0A8C0SV77, A0A8I3NFI4
    Conserved Domains (2) summary
    PRK07045
    Location:121 → 426
    PRK07045; putative monooxygenase; Reviewed
    cl21454
    Location:276 → 547
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  2. XM_038555497.1 → XP_038411425.1  squalene monooxygenase

    UniProtKB/TrEMBL
    A0A8C0K1C6, A0A8C0MWQ3, A0A8C0SV77, A0A8I3NFI4
    Conserved Domains (2) summary
    PRK07045
    Location:121 → 426
    PRK07045; putative monooxygenase; Reviewed
    cl21454
    Location:276 → 547
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006595.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    22958181..22982327
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005627934.4 → XP_005627991.1  squalene monooxygenase

    See identical proteins and their annotated locations for XP_005627991.1

    UniProtKB/TrEMBL
    A0A8C0K1C6, A0A8C0MWQ3, A0A8C0SV77, A0A8I3NFI4
    Conserved Domains (2) summary
    PRK07045
    Location:121 → 426
    PRK07045; putative monooxygenase; Reviewed
    cl21454
    Location:276 → 547
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  2. XM_005627933.4 → XP_005627990.1  squalene monooxygenase

    See identical proteins and their annotated locations for XP_005627990.1

    UniProtKB/TrEMBL
    A0A8C0K1C6, A0A8C0MWQ3, A0A8C0SV77, A0A8I3NFI4
    Conserved Domains (2) summary
    PRK07045
    Location:121 → 426
    PRK07045; putative monooxygenase; Reviewed
    cl21454
    Location:276 → 547
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
Nucleotide Protein
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