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CREB1 cAMP responsive element binding protein 1 [ Canis lupus familiaris (dog) ]

Gene ID: 607922, updated on 5-Mar-2024

Summary

Official Symbol
CREB1provided by VGNC
Official Full Name
cAMP responsive element binding protein 1provided by VGNC
Primary source
VGNC:VGNC:39595
See related
Ensembl:ENSCAFG00845022020
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

Location:
chromosome: 37
Exon count:
10
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 37 NC_051841.1 (15856953..15919649)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 37 NC_006619.4 (16804994..16867966)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 37 NC_049258.1 (15785052..15847761)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 37 NC_049297.1 (15802749..15865587)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 37 NC_049778.1 (15775840..15838520)

Chromosome 37 - NC_051841.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102156884 Neighboring gene uncharacterized LOC111094350 Neighboring gene uncharacterized LOC119867947 Neighboring gene uncharacterized LOC119867946 Neighboring gene methyltransferase 21A, HSPA lysine Neighboring gene uncharacterized LOC119867948 Neighboring gene uncharacterized LOC102157126

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
PubMed 
enables cAMP response element binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of ATF4-CREB1 transcription factor complex IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
cyclic AMP-responsive element-binding protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051841.1 Reference ROS_Cfam_1.0

    Range
    15856953..15919649
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038447771.1XP_038303699.1  cyclic AMP-responsive element-binding protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0N7M6, A0A8I3S2U7
    Related
    ENSCAFP00845030437.1, ENSCAFT00845038863.1
    Conserved Domains (2) summary
    cd14690
    Location:285339
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:113151
    pKID; pKID domain
  2. XM_038447770.1XP_038303698.1  cyclic AMP-responsive element-binding protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0N7M6, A0A8I3S2U7
    Conserved Domains (2) summary
    cd14690
    Location:285339
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:113151
    pKID; pKID domain
  3. XM_038447772.1XP_038303700.1  cyclic AMP-responsive element-binding protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LTC9, A0A8C0TY64, A0A8I3PDE7
    Related
    ENSCAFP00845030502.1, ENSCAFT00845038947.1
    Conserved Domains (2) summary
    cd14690
    Location:271325
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:99137
    pKID; pKID domain
  4. XM_038447773.1XP_038303701.1  cyclic AMP-responsive element-binding protein 1 isoform X3

    Conserved Domains (1) summary
    cd14690
    Location:55109
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain

RNA

  1. XR_005308396.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049297.1 Alternate UMICH_Zoey_3.1

    Range
    15802749..15865587
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038521838.1XP_038377766.1  cyclic AMP-responsive element-binding protein 1 isoform X1

    Conserved Domains (2) summary
    cd14690
    Location:285339
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:113151
    pKID; pKID domain
  2. XM_038521837.1XP_038377765.1  cyclic AMP-responsive element-binding protein 1 isoform X1

    Conserved Domains (2) summary
    cd14690
    Location:285339
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:113151
    pKID; pKID domain
  3. XM_038521839.1XP_038377767.1  cyclic AMP-responsive element-binding protein 1 isoform X2

    Conserved Domains (2) summary
    cd14690
    Location:271325
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:99137
    pKID; pKID domain
  4. XM_038521840.1XP_038377768.1  cyclic AMP-responsive element-binding protein 1 isoform X3

    Conserved Domains (1) summary
    cd14690
    Location:55109
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain

RNA

  1. XR_005351334.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049778.1 Alternate UNSW_CanFamBas_1.0

    Range
    15775840..15838520
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038649943.1XP_038505871.1  cyclic AMP-responsive element-binding protein 1 isoform X1

    Conserved Domains (2) summary
    cd14690
    Location:285339
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:113151
    pKID; pKID domain
  2. XM_038649942.1XP_038505870.1  cyclic AMP-responsive element-binding protein 1 isoform X1

    Conserved Domains (2) summary
    cd14690
    Location:285339
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:113151
    pKID; pKID domain
  3. XM_038649944.1XP_038505872.1  cyclic AMP-responsive element-binding protein 1 isoform X2

    Conserved Domains (2) summary
    cd14690
    Location:271325
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:99137
    pKID; pKID domain
  4. XM_038649945.1XP_038505873.1  cyclic AMP-responsive element-binding protein 1 isoform X3

    Conserved Domains (1) summary
    cd14690
    Location:55109
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain

RNA

  1. XR_005419048.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049258.1 Alternate UU_Cfam_GSD_1.0

    Range
    15785052..15847761
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038585557.1XP_038441485.1  cyclic AMP-responsive element-binding protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0N7M6, A0A8I3S2U7
    Conserved Domains (2) summary
    cd14690
    Location:285339
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:113151
    pKID; pKID domain
  2. XM_038585556.1XP_038441484.1  cyclic AMP-responsive element-binding protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0N7M6, A0A8I3S2U7
    Conserved Domains (2) summary
    cd14690
    Location:285339
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:113151
    pKID; pKID domain
  3. XM_038585558.1XP_038441486.1  cyclic AMP-responsive element-binding protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LTC9, A0A8C0TY64, A0A8I3PDE7
    Conserved Domains (2) summary
    cd14690
    Location:271325
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:99137
    pKID; pKID domain
  4. XM_038585559.1XP_038441487.1  cyclic AMP-responsive element-binding protein 1 isoform X3

    Conserved Domains (1) summary
    cd14690
    Location:55109
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain

RNA

  1. XR_005385303.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006619.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    16804994..16867966
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014110991.3XP_013966466.1  cyclic AMP-responsive element-binding protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0N7M6, A0A8I3S2U7
    Conserved Domains (2) summary
    cd14690
    Location:285339
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:113151
    pKID; pKID domain
  2. XM_014110990.3XP_013966465.1  cyclic AMP-responsive element-binding protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0N7M6, A0A8I3S2U7
    Conserved Domains (2) summary
    cd14690
    Location:285339
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:113151
    pKID; pKID domain
  3. XM_014110992.3XP_013966467.1  cyclic AMP-responsive element-binding protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LTC9, A0A8C0TY64, A0A8I3PDE7
    Conserved Domains (2) summary
    cd14690
    Location:271325
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:99137
    pKID; pKID domain
  4. XM_038463756.1XP_038319684.1  cyclic AMP-responsive element-binding protein 1 isoform X3

    Conserved Domains (1) summary
    cd14690
    Location:55109
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain

RNA

  1. XR_005318408.1 RNA Sequence