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ESPL1 extra spindle pole bodies like 1, separase [ Canis lupus familiaris (dog) ]

Gene ID: 607879, updated on 5-Mar-2024

Summary

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Official Symbol
ESPL1provided by VGNC
Official Full Name
extra spindle pole bodies like 1, separaseprovided by VGNC
Primary source
VGNC:VGNC:40475
See related
Ensembl:ENSCAFG00845020502
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 27
Exon count:
31
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 27 NC_051831.1 (1915651..1938901, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 27 NC_006609.4 (44314872..44338083)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 27 NC_049248.1 (44715570..44738805)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 27 NC_049287.1 (1933939..1957164, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 27 NC_049768.1 (1918870..1942108, complement)

Chromosome 27 - NC_051831.1Genomic Context describing neighboring genes Neighboring gene MYG1 exonuclease Neighboring gene ribosomal protein L30 pseudogene Neighboring gene prefoldin subunit 5 Neighboring gene translation initiation factor IF-2-like Neighboring gene major facilitator superfamily domain containing 5 Neighboring gene uncharacterized LOC111092799 Neighboring gene retinoic acid receptor gamma

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in meiotic chromosome separation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in centrosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitotic spindle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
separin
Names
extra spindle pole bodies homolog 1
extra spindle poles-like protein 1
XP_005636831.2
XP_038293995.1
XP_038293996.1
XP_038368696.1
XP_038368697.1
XP_038433706.1
XP_038433707.1
XP_038496454.1
XP_038496455.1
XP_849828.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051831.1 Reference ROS_Cfam_1.0

    Range
    1915651..1938901 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038438068.1 → XP_038293996.1  separin

    UniProtKB/TrEMBL
    A0A8C0RT85, A0A8C0TIR5, A0A8I3S1V2
    Conserved Domains (1) summary
    pfam03568
    Location:1709 → 2057
    Peptidase_C50; Peptidase family C50

  2. XM_038438067.1 → XP_038293995.1  separin

    UniProtKB/TrEMBL
    A0A8C0RT85, A0A8C0TIR5, A0A8I3S1V2
    Related
    ENSCAFP00845028498.1, ENSCAFT00845036409.1
    Conserved Domains (1) summary
    pfam03568
    Location:1709 → 2057
    Peptidase_C50; Peptidase family C50

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049287.1 Alternate UMICH_Zoey_3.1

    Range
    1933939..1957164 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038512769.1 → XP_038368697.1  separin

    Conserved Domains (1) summary
    pfam03568
    Location:1709 → 2057
    Peptidase_C50; Peptidase family C50

  2. XM_038512768.1 → XP_038368696.1  separin

    Conserved Domains (1) summary
    pfam03568
    Location:1709 → 2057
    Peptidase_C50; Peptidase family C50

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049768.1 Alternate UNSW_CanFamBas_1.0

    Range
    1918870..1942108 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038640527.1 → XP_038496455.1  separin

  2. XM_038640526.1 → XP_038496454.1  separin

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049248.1 Alternate UU_Cfam_GSD_1.0

    Range
    44715570..44738805
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038577778.1 → XP_038433706.1  separin

    UniProtKB/TrEMBL
    A0A8C0RT85, A0A8C0TIR5, A0A8I3S1V2
    Conserved Domains (1) summary
    pfam03568
    Location:1709 → 2057
    Peptidase_C50; Peptidase family C50

  2. XM_038577779.1 → XP_038433707.1  separin

    UniProtKB/TrEMBL
    A0A8C0RT85, A0A8C0TIR5, A0A8I3S1V2
    Conserved Domains (1) summary
    pfam03568
    Location:1709 → 2057
    Peptidase_C50; Peptidase family C50

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006609.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    44314872..44338083
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005636774.3 → XP_005636831.2  separin

    UniProtKB/TrEMBL
    A0A8C0RT85, A0A8C0TIR5, A0A8I3S1V2
    Conserved Domains (1) summary
    pfam03568
    Location:1709 → 2057
    Peptidase_C50; Peptidase family C50

  2. XM_844735.5 → XP_849828.3  separin

    UniProtKB/TrEMBL
    A0A8C0RT85, A0A8C0TIR5, A0A8I3S1V2
    Conserved Domains (1) summary
    pfam03568
    Location:1709 → 2057
    Peptidase_C50; Peptidase family C50
Nucleotide Protein
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