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LPIN2 lipin 2 [ Canis lupus familiaris (dog) ]

Gene ID: 607640, updated on 5-Mar-2024

Summary

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Official Symbol
LPIN2provided by VGNC
Official Full Name
lipin 2provided by VGNC
Primary source
VGNC:VGNC:42752
See related
Ensembl:ENSCAFG00845002673
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 7
Exon count:
23
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 7 NC_051811.1 (69645593..69726459, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 7 NC_006589.4 (69038655..69119523, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 7 NC_049228.1 (69645434..69726575, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 7 NC_049267.1 (69327908..69408884, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 7 NC_049748.1 (69347982..69428812, complement)

Chromosome 7 - NC_051811.1Genomic Context describing neighboring genes Neighboring gene structural maintenance of chromosomes flexible hinge domain containing 1 Neighboring gene elastin microfibril interfacer 2 Neighboring gene NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10-like Neighboring gene uncharacterized LOC119872607 Neighboring gene myomesin 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phosphatidate phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription coactivator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to insulin stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fatty acid catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in triglyceride biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidate phosphatase LPIN2
XP_005623091.3
XP_005623093.1
XP_022277255.1
XP_038338210.1
XP_038338211.1
XP_038338212.1
XP_038338213.1
XP_038399645.1
XP_038399646.1
XP_038399647.1
XP_038399648.1
XP_038463771.1
XP_038463772.1
XP_038463773.1
XP_038463774.1
XP_038528450.1
XP_038528451.1
XP_038528452.1
XP_038528453.1
XP_849491.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051811.1 Reference ROS_Cfam_1.0

    Range
    69645593..69726459 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038672523.1 → XP_038528451.1  phosphatidate phosphatase LPIN2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0L4R6, A0A8I3RQV6, A0A8P0NTR6
    Related
    ENSCAFP00845003799.1, ENSCAFT00845004750.1
    Conserved Domains (4) summary
    pfam04571
    Location:1 → 107
    Lipin_N; lipin, N-terminal conserved region
    pfam08235
    Location:641 → 866
    LNS2; LNS2 (Lipin/Ned1/Smp2)
    pfam15017
    Location:879 → 897
    WRNPLPNID; Putative WW-binding domain and destruction box
    pfam16876
    Location:473 → 564
    Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain

  2. XM_038672524.1 → XP_038528452.1  phosphatidate phosphatase LPIN2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0L4R6, A0A8I3RQV6, A0A8P0NTR6
    Conserved Domains (4) summary
    pfam04571
    Location:1 → 107
    Lipin_N; lipin, N-terminal conserved region
    pfam08235
    Location:641 → 866
    LNS2; LNS2 (Lipin/Ned1/Smp2)
    pfam15017
    Location:879 → 897
    WRNPLPNID; Putative WW-binding domain and destruction box
    pfam16876
    Location:473 → 564
    Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain

  3. XM_038672525.1 → XP_038528453.1  phosphatidate phosphatase LPIN2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0L4R6, A0A8I3RQV6, A0A8P0NTR6
    Conserved Domains (4) summary
    pfam04571
    Location:1 → 107
    Lipin_N; lipin, N-terminal conserved region
    pfam08235
    Location:641 → 866
    LNS2; LNS2 (Lipin/Ned1/Smp2)
    pfam15017
    Location:879 → 897
    WRNPLPNID; Putative WW-binding domain and destruction box
    pfam16876
    Location:473 → 564
    Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain

  4. XM_038672522.1 → XP_038528450.1  phosphatidate phosphatase LPIN2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0RHZ1, A0A8C0RW32, A0A8I3MLN7
    Related
    ENSCAFP00845003804.1, ENSCAFT00845004754.1
    Conserved Domains (4) summary
    pfam04571
    Location:42 → 148
    Lipin_N; lipin, N-terminal conserved region
    pfam08235
    Location:682 → 907
    LNS2; LNS2 (Lipin/Ned1/Smp2)
    pfam15017
    Location:920 → 938
    WRNPLPNID; Putative WW-binding domain and destruction box
    pfam16876
    Location:514 → 605
    Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049267.1 Alternate UMICH_Zoey_3.1

    Range
    69327908..69408884 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038482283.1 → XP_038338211.1  phosphatidate phosphatase LPIN2 isoform X2

  2. XM_038482284.1 → XP_038338212.1  phosphatidate phosphatase LPIN2 isoform X2

  3. XM_038482285.1 → XP_038338213.1  phosphatidate phosphatase LPIN2 isoform X2

  4. XM_038482282.1 → XP_038338210.1  phosphatidate phosphatase LPIN2 isoform X1

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049748.1 Alternate UNSW_CanFamBas_1.0

    Range
    69347982..69428812 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038607844.1 → XP_038463772.1  phosphatidate phosphatase LPIN2 isoform X2

    Conserved Domains (4) summary
    pfam04571
    Location:1 → 107
    Lipin_N; lipin, N-terminal conserved region
    pfam08235
    Location:641 → 866
    LNS2; LNS2 (Lipin/Ned1/Smp2)
    pfam15017
    Location:879 → 897
    WRNPLPNID; Putative WW-binding domain and destruction box
    pfam16876
    Location:473 → 564
    Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain

  2. XM_038607845.1 → XP_038463773.1  phosphatidate phosphatase LPIN2 isoform X2

    Conserved Domains (4) summary
    pfam04571
    Location:1 → 107
    Lipin_N; lipin, N-terminal conserved region
    pfam08235
    Location:641 → 866
    LNS2; LNS2 (Lipin/Ned1/Smp2)
    pfam15017
    Location:879 → 897
    WRNPLPNID; Putative WW-binding domain and destruction box
    pfam16876
    Location:473 → 564
    Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain

  3. XM_038607846.1 → XP_038463774.1  phosphatidate phosphatase LPIN2 isoform X2

    Conserved Domains (4) summary
    pfam04571
    Location:1 → 107
    Lipin_N; lipin, N-terminal conserved region
    pfam08235
    Location:641 → 866
    LNS2; LNS2 (Lipin/Ned1/Smp2)
    pfam15017
    Location:879 → 897
    WRNPLPNID; Putative WW-binding domain and destruction box
    pfam16876
    Location:473 → 564
    Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain

  4. XM_038607843.1 → XP_038463771.1  phosphatidate phosphatase LPIN2 isoform X1

    Conserved Domains (4) summary
    pfam04571
    Location:42 → 148
    Lipin_N; lipin, N-terminal conserved region
    pfam08235
    Location:682 → 907
    LNS2; LNS2 (Lipin/Ned1/Smp2)
    pfam15017
    Location:920 → 938
    WRNPLPNID; Putative WW-binding domain and destruction box
    pfam16876
    Location:514 → 605
    Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049228.1 Alternate UU_Cfam_GSD_1.0

    Range
    69645434..69726575 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038543718.1 → XP_038399646.1  phosphatidate phosphatase LPIN2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0L4R6, A0A8I3RQV6, A0A8P0NTR6
    Conserved Domains (4) summary
    pfam04571
    Location:1 → 107
    Lipin_N; lipin, N-terminal conserved region
    pfam08235
    Location:641 → 866
    LNS2; LNS2 (Lipin/Ned1/Smp2)
    pfam15017
    Location:879 → 897
    WRNPLPNID; Putative WW-binding domain and destruction box
    pfam16876
    Location:473 → 564
    Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain

  2. XM_038543719.1 → XP_038399647.1  phosphatidate phosphatase LPIN2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0L4R6, A0A8I3RQV6, A0A8P0NTR6
    Conserved Domains (4) summary
    pfam04571
    Location:1 → 107
    Lipin_N; lipin, N-terminal conserved region
    pfam08235
    Location:641 → 866
    LNS2; LNS2 (Lipin/Ned1/Smp2)
    pfam15017
    Location:879 → 897
    WRNPLPNID; Putative WW-binding domain and destruction box
    pfam16876
    Location:473 → 564
    Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain

  3. XM_038543720.1 → XP_038399648.1  phosphatidate phosphatase LPIN2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0L4R6, A0A8I3RQV6, A0A8P0NTR6
    Conserved Domains (4) summary
    pfam04571
    Location:1 → 107
    Lipin_N; lipin, N-terminal conserved region
    pfam08235
    Location:641 → 866
    LNS2; LNS2 (Lipin/Ned1/Smp2)
    pfam15017
    Location:879 → 897
    WRNPLPNID; Putative WW-binding domain and destruction box
    pfam16876
    Location:473 → 564
    Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain

  4. XM_038543717.1 → XP_038399645.1  phosphatidate phosphatase LPIN2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0RHZ1, A0A8C0RW32, A0A8I3MLN7
    Conserved Domains (4) summary
    pfam04571
    Location:42 → 148
    Lipin_N; lipin, N-terminal conserved region
    pfam08235
    Location:682 → 907
    LNS2; LNS2 (Lipin/Ned1/Smp2)
    pfam15017
    Location:920 → 938
    WRNPLPNID; Putative WW-binding domain and destruction box
    pfam16876
    Location:514 → 605
    Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006589.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    69038655..69119523 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_844398.6 → XP_849491.1  phosphatidate phosphatase LPIN2 isoform X2

    See identical proteins and their annotated locations for XP_849491.1

    UniProtKB/TrEMBL
    A0A8C0L4R6, A0A8I3RQV6, A0A8P0NTR6
    Conserved Domains (4) summary
    pfam04571
    Location:1 → 107
    Lipin_N; lipin, N-terminal conserved region
    pfam08235
    Location:641 → 866
    LNS2; LNS2 (Lipin/Ned1/Smp2)
    pfam15017
    Location:879 → 897
    WRNPLPNID; Putative WW-binding domain and destruction box
    pfam16876
    Location:473 → 564
    Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain

  2. XM_005623036.4 → XP_005623093.1  phosphatidate phosphatase LPIN2 isoform X2

    See identical proteins and their annotated locations for XP_005623093.1

    UniProtKB/TrEMBL
    A0A8C0L4R6, A0A8I3RQV6, A0A8P0NTR6
    Conserved Domains (4) summary
    pfam04571
    Location:1 → 107
    Lipin_N; lipin, N-terminal conserved region
    pfam08235
    Location:641 → 866
    LNS2; LNS2 (Lipin/Ned1/Smp2)
    pfam15017
    Location:879 → 897
    WRNPLPNID; Putative WW-binding domain and destruction box
    pfam16876
    Location:473 → 564
    Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain

  3. XM_022421547.2 → XP_022277255.1  phosphatidate phosphatase LPIN2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0L4R6, A0A8I3RQV6, A0A8P0NTR6
    Conserved Domains (4) summary
    pfam04571
    Location:1 → 107
    Lipin_N; lipin, N-terminal conserved region
    pfam08235
    Location:641 → 866
    LNS2; LNS2 (Lipin/Ned1/Smp2)
    pfam15017
    Location:879 → 897
    WRNPLPNID; Putative WW-binding domain and destruction box
    pfam16876
    Location:473 → 564
    Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain

  4. XM_005623034.4 → XP_005623091.3  phosphatidate phosphatase LPIN2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0RHZ1, A0A8C0RW32, A0A8I3MLN7
    Conserved Domains (4) summary
    pfam04571
    Location:42 → 148
    Lipin_N; lipin, N-terminal conserved region
    pfam08235
    Location:682 → 907
    LNS2; LNS2 (Lipin/Ned1/Smp2)
    pfam15017
    Location:920 → 938
    WRNPLPNID; Putative WW-binding domain and destruction box
    pfam16876
    Location:514 → 605
    Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain
Nucleotide Protein
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