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DDIT3 DNA damage inducible transcript 3 [ Canis lupus familiaris (dog) ]

Gene ID: 607439, updated on 5-Mar-2024

Summary

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Official Symbol
DDIT3provided by VGNC
Official Full Name
DNA damage inducible transcript 3provided by VGNC
Primary source
VGNC:VGNC:39836
See related
Ensembl:ENSCAFG00845012093
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
5
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 10 NC_051814.1 (1615759..1621400, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 10 NC_006592.4 (1669927..1675567, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 10 NC_049231.1 (1960652..1966292, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 10 NC_049270.1 (1593774..1599407, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 10 NC_049751.1 (1835463..1841297, complement)

Chromosome 10 - NC_051814.1Genomic Context describing neighboring genes Neighboring gene GLI family zinc finger 1 Neighboring gene Rho GTPase activating protein 9 Neighboring gene methionyl-tRNA synthetase 1 Neighboring gene methyl-CpG binding domain protein 6 Neighboring gene dynactin subunit 2 Neighboring gene kinesin family member 5A Neighboring gene uncharacterized LOC119873572

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription factor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ER overload response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of CREB transcription factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of intrinsic apoptotic signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of CHOP-ATF3 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of CHOP-ATF4 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of CHOP-C/EBP complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA damage-inducible transcript 3 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051814.1 Reference ROS_Cfam_1.0

    Range
    1615759..1621400 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038679111.1 → XP_038535039.1  DNA damage-inducible transcript 3 protein

    UniProtKB/TrEMBL
    A0A8C0LCI5, A0A8C0MS70, A0A8I3NHJ0
    Conserved Domains (2) summary
    smart00338
    Location:95 → 160
    BRLZ; basic region leucin zipper
    cd14686
    Location:98 → 152
    bZIP; coiled coil [structural motif]

  2. XM_038679110.1 → XP_038535038.1  DNA damage-inducible transcript 3 protein

    UniProtKB/TrEMBL
    A0A8C0LCI5, A0A8C0MS70, A0A8I3NHJ0
    Related
    ENSCAFP00845016899.1, ENSCAFT00845021502.1
    Conserved Domains (2) summary
    smart00338
    Location:95 → 160
    BRLZ; basic region leucin zipper
    cd14686
    Location:98 → 152
    bZIP; coiled coil [structural motif]

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049270.1 Alternate UMICH_Zoey_3.1

    Range
    1593774..1599407 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038487895.1 → XP_038343823.1  DNA damage-inducible transcript 3 protein

    Conserved Domains (2) summary
    smart00338
    Location:95 → 160
    BRLZ; basic region leucin zipper
    cd14686
    Location:98 → 152
    bZIP; coiled coil [structural motif]

  2. XM_038487894.1 → XP_038343822.1  DNA damage-inducible transcript 3 protein

    Conserved Domains (2) summary
    smart00338
    Location:95 → 160
    BRLZ; basic region leucin zipper
    cd14686
    Location:98 → 152
    bZIP; coiled coil [structural motif]

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049751.1 Alternate UNSW_CanFamBas_1.0

    Range
    1835463..1841297 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038613751.1 → XP_038469679.1  DNA damage-inducible transcript 3 protein

    Conserved Domains (2) summary
    smart00338
    Location:95 → 160
    BRLZ; basic region leucin zipper
    cd14686
    Location:98 → 152
    bZIP; coiled coil [structural motif]

  2. XM_038613750.1 → XP_038469678.1  DNA damage-inducible transcript 3 protein

    Conserved Domains (2) summary
    smart00338
    Location:95 → 160
    BRLZ; basic region leucin zipper
    cd14686
    Location:98 → 152
    bZIP; coiled coil [structural motif]

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049231.1 Alternate UU_Cfam_GSD_1.0

    Range
    1960652..1966292 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038549789.1 → XP_038405717.1  DNA damage-inducible transcript 3 protein

    UniProtKB/TrEMBL
    A0A8C0LCI5, A0A8C0MS70, A0A8I3NHJ0
    Conserved Domains (2) summary
    smart00338
    Location:95 → 160
    BRLZ; basic region leucin zipper
    cd14686
    Location:98 → 152
    bZIP; coiled coil [structural motif]

  2. XM_038549788.1 → XP_038405716.1  DNA damage-inducible transcript 3 protein

    UniProtKB/TrEMBL
    A0A8C0LCI5, A0A8C0MS70, A0A8I3NHJ0
    Conserved Domains (2) summary
    smart00338
    Location:95 → 160
    BRLZ; basic region leucin zipper
    cd14686
    Location:98 → 152
    bZIP; coiled coil [structural motif]

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006592.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    1669927..1675567 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022424097.2 → XP_022279805.1  DNA damage-inducible transcript 3 protein

    UniProtKB/TrEMBL
    A0A8C0LCI5, A0A8C0MS70, A0A8I3NHJ0
    Conserved Domains (2) summary
    smart00338
    Location:95 → 160
    BRLZ; basic region leucin zipper
    cd14686
    Location:98 → 152
    bZIP; coiled coil [structural motif]

  2. XM_014117187.3 → XP_013972662.1  DNA damage-inducible transcript 3 protein

    UniProtKB/TrEMBL
    A0A8C0LCI5, A0A8C0MS70, A0A8I3NHJ0
    Conserved Domains (2) summary
    smart00338
    Location:95 → 160
    BRLZ; basic region leucin zipper
    cd14686
    Location:98 → 152
    bZIP; coiled coil [structural motif]
Nucleotide Protein
Heading Accession and Version

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