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HES6 hes family bHLH transcription factor 6 [ Canis lupus familiaris (dog) ]

Gene ID: 607298, updated on 5-Mar-2024

Summary

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Official Symbol
HES6provided by VGNC
Official Full Name
hes family bHLH transcription factor 6provided by VGNC
Primary source
VGNC:VGNC:59081
See related
Ensembl:ENSCAFG00845029909
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 25
Exon count:
4
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 25 NC_051829.1 (49096318..49098006, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 25 NC_006607.4 (49206100..49207791, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 25 NC_049246.1 (48992417..48994109, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 25 NC_049285.1 (48971418..48973122, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 25 NC_049766.1 (48760071..48761750, complement)

Chromosome 25 - NC_051829.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119865980 Neighboring gene uncharacterized LOC119865979 Neighboring gene uncharacterized LOC119865981 Neighboring gene period circadian regulator 2 Neighboring gene uncharacterized LOC106557800 Neighboring gene uncharacterized LOC111092397

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome-wide identification and analysis of basic helix-loop-helix domains in dog, Canis lupus familiaris. Wang XH, et al. Mol Genet Genomics, 2015 Apr. PMID 25403511

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in anterior/posterior pattern specification IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of neurogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transcription cofactor HES-6
Names
hairy and enhancer of split 6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051829.1 Reference ROS_Cfam_1.0

    Range
    49096318..49098006 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038434647.1 → XP_038290575.1  transcription cofactor HES-6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LLA0, A0A8C0TAM7, A0A8I3SCH4
    Related
    ENSCAFP00845041620.1, ENSCAFT00845053011.1
    Conserved Domains (2) summary
    pfam07527
    Location:96 → 134
    Hairy_orange; Hairy Orange
    cl00081
    Location:24 → 81
    bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

  2. XM_038434648.1 → XP_038290576.1  transcription cofactor HES-6 isoform X2

    Conserved Domains (1) summary
    cl00081
    Location:24 → 70
    bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049285.1 Alternate UMICH_Zoey_3.1

    Range
    48971418..48973122 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038511060.1 → XP_038366988.1  transcription cofactor HES-6 isoform X1

    Conserved Domains (2) summary
    pfam07527
    Location:96 → 134
    Hairy_orange; Hairy Orange
    cl00081
    Location:24 → 81
    bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

  2. XM_038511061.1 → XP_038366989.1  transcription cofactor HES-6 isoform X2

    Conserved Domains (1) summary
    cl00081
    Location:24 → 70
    bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049766.1 Alternate UNSW_CanFamBas_1.0

    Range
    48760071..48761750 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038637332.1 → XP_038493260.1  transcription cofactor HES-6 isoform X1

    Conserved Domains (2) summary
    pfam07527
    Location:96 → 134
    Hairy_orange; Hairy Orange
    cl00081
    Location:24 → 81
    bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

  2. XM_038637333.1 → XP_038493261.1  transcription cofactor HES-6 isoform X2

    Conserved Domains (1) summary
    cl00081
    Location:24 → 70
    bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049246.1 Alternate UU_Cfam_GSD_1.0

    Range
    48992417..48994109 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038573095.1 → XP_038429023.1  transcription cofactor HES-6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LLA0, A0A8C0TAM7, A0A8I3SCH4
    Conserved Domains (2) summary
    pfam07527
    Location:96 → 134
    Hairy_orange; Hairy Orange
    cl00081
    Location:24 → 81
    bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

  2. XM_038573096.1 → XP_038429024.1  transcription cofactor HES-6 isoform X2

    Conserved Domains (1) summary
    cl00081
    Location:24 → 70
    bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006607.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    49206100..49207791 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038458417.1 → XP_038314345.1  transcription cofactor HES-6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LLA0, A0A8C0TAM7, A0A8I3SCH4
    Conserved Domains (2) summary
    pfam07527
    Location:96 → 134
    Hairy_orange; Hairy Orange
    cl00081
    Location:24 → 81
    bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

  2. XM_038458418.1 → XP_038314346.1  transcription cofactor HES-6 isoform X2

    Conserved Domains (1) summary
    cl00081
    Location:24 → 70
    bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily
Nucleotide Protein
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